The Positive Inotropic Effect of Relaxin-2 in Human Atrial Myocardium is Preserved in End-Stage Heart Failure: Role of Gi-Phosphoinositide-3 Kinase Signaling

2011 ◽  
Vol 17 (2) ◽  
pp. 158-166 ◽  
Author(s):  
Thomas Dschietzig ◽  
Konstantin Alexiou ◽  
Hans-Tilman Kinkel ◽  
Gert Baumann ◽  
Klaus Matschke ◽  
...  
Keyword(s):  
Heart Failure ◽  
Positive Inotropic Effect ◽  
Inotropic Effect ◽  
Kinase Signaling ◽  
Atrial Myocardium ◽  
End Stage Heart Failure ◽  
Relaxin 2 ◽  
Phosphoinositide 3 Kinase ◽  
End Stage

scholarly journals Role of Cardiac Resynchronization in End-Stage Heart Failure Patients Requiring Inotrope Therapy

2010 ◽  
Vol 16 (12) ◽  
pp. 931-937 ◽  
Author(s):  
Sanjoy Bhattacharya ◽  
Kaleab Abebe ◽  
Marc Simon ◽  
Samir Saba ◽  
Evan Adelstein
Keyword(s):  
Heart Failure ◽  
Cardiac Resynchronization ◽  
Heart Failure Patients ◽  
End Stage Heart Failure ◽  
End Stage

scholarly journals Mechanical Circulatory Support and the Role of LVADs in Heart Failure Therapy

2015 ◽  
Vol 9s2 ◽  
pp. CMC.S19694 ◽  
Author(s):  
Allison McLarty
Keyword(s):  
United States ◽  
Heart Failure ◽  
The United States ◽  
Left Ventricular ◽  
Circulatory Support ◽  
Final Destination ◽  
End Stage Heart Failure ◽  
Maximal Medical Therapy ◽  
End Stage

Heart failure is epidemic in the United States with a prevalence of over 5 million. The diagnosis carries a mortality risk of 50% at 5 years rivaling many diagnoses of cancer. Heart transplantation, long the “gold standard” treatment for end stage heart failure unresponsive to maximal medical therapy falls way short of meeting the need with only about 2,000 transplants performed annually in the United States due to donor limitation. Left ventricular devices have emerged as a viable option for patients as both a “bridge to transplantation” and as a final “destination therapy”.

scholarly journals The role of long-term mechanical circulatory support in the treatment of end-stage heart failure

2019 ◽  
pp. 331-340
Author(s):  
Lech Paluszkiewicz ◽  
Tomasz Kukulski ◽  
Michał Zembala ◽  
Jan Gummert ◽  
Michiel Morshuis
Keyword(s):  
Heart Failure ◽  
Mechanical Circulatory Support ◽  
Circulatory Support ◽  
End Stage Heart Failure ◽  
End Stage

Relaxin-2 may offer therapeutic advantages in end-stage heart failure

2012 ◽  
Vol 157 (3) ◽  
pp. 432-433 ◽  
Author(s):  
Zhiqiang Zhao ◽  
Tong Liu ◽  
Guangping Li
Keyword(s):  
Heart Failure ◽  
End Stage Heart Failure ◽  
Relaxin 2 ◽  
End Stage
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