Metal-organic framework-based nanomaterials for biomedical applications

2020 ◽  
Vol 31 (5) ◽  
pp. 1060-1070 ◽  
Author(s):  
Shu Zhang ◽  
Xibo Pei ◽  
Huile Gao ◽  
Song Chen ◽  
Jian Wang
Keyword(s):  
Biomedical Applications ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Organic Framework

Multifunctional metal–organic framework heterostructures for enhanced cancer therapy

2021 ◽  
Author(s):  
Jintong Liu ◽  
Jing Huang ◽  
Lei Zhang ◽  
Jianping Lei
Keyword(s):  
Cancer Therapy ◽  
General Principle ◽  
Biomedical Applications ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Functional Modulation ◽  
Organic Framework

We review the general principle of the design and functional modulation of nanoscaled MOF heterostructures, and biomedical applications in enhanced therapy.

Biomedical applications of metal-organic framework (MOF) based nano-enzymes

2021 ◽  
Author(s):  
Jian-Qiang Liu ◽  
Abhinav Kumar ◽  
Dong Liu ◽  
Manoj Trivedi ◽  
Yubin Zhou ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Metal Organic Framework ◽  
Practical Applications ◽  
Metal Organic ◽  
Organic Framework

Natural enzymes are highly specific biocatalysts that can selectively catalyse specific biological reactions. However, their high preparation cost and easy deactivation of natural enzymes limit their practical applications. In the...

scholarly journals Aptamer-Modified DNA Tetrahedra-Gated Metal-Organic Framework Nanoparticle Carriers for Enhanced Chemotherapy or Photodynamic Therapy

2021 ◽  
Author(s):  
Pu Zhang ◽  
Amit Fischer ◽  
Yu Ouyang ◽  
Jianbang Wang ◽  
Sohn Yang Sung ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Biomedical Applications ◽  
Metal Organic Framework ◽  
Modified Dna ◽  
Metal Organic ◽  
Organic Framework

UiO-66 metal-organic framework nanoparticles (NMOFs) gated by aptamer-functionalized DNA tetrahedra provide superior biomarker-responsive hybrid nano-carriers for biomedical applications. Hybrid nano-carriers consisting of ATP-aptamer or VEGF-aptamer functionalized tetrahedra-gated NMOFs are loaded...

Alkali/alkaline earth-based metal–organic frameworks on biomedical applications

2021 ◽  
Author(s):  
Jian-Qiang Liu ◽  
Gaomin Ye ◽  
Chen Chen ◽  
Jingzhe Lin ◽  
Xinsheng Peng ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Alkaline Earth ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Three Dimensional ◽  
Metal Organic ◽  
Application Prospects ◽  
Organic Framework

With steady development of metal-organic framework (MOF) materials, this peculiar class of three-dimensional materials finds application prospects in myriad of areas. The integration of different metals with varied categories of...

scholarly journals Polymer/Metal Organic Framework (MOF) Nanocomposites for Biomedical Applications

Molecules ◽  
2020 ◽  
Vol 25 (1) ◽  
pp. 185 ◽  
Author(s):  
Dimitrios Giliopoulos ◽  
Alexandra Zamboulis ◽  
Dimitrios Giannakoudakis ◽  
Dimitrios Bikiaris ◽  
Konstantinos Triantafyllidis
Keyword(s):  
Biomedical Applications ◽  
Structural Characteristics ◽  
Metal Organic Framework ◽  
Covalent Attachment ◽  
Synthesis Methods ◽  
Critical Comparison ◽  
Composite Systems ◽  
Polymer Metal ◽  
Metal Organic ◽  
Organic Framework

The utilization of polymer/metal organic framework (MOF) nanocomposites in various biomedical applications has been widely studied due to their unique properties that arise from MOFs or hybrid composite systems. This review focuses on the types of polymer/MOF nanocomposites used in drug delivery and imaging applications. Initially, a comprehensive introduction to the synthesis and structure of MOFs and bio-MOFs is presented. Subsequently, the properties and the performance of polymer/MOF nanocomposites used in these applications are examined, in relation to the approach applied for their synthesis: (i) non-covalent attachment, (ii) covalent attachment, (iii) polymer coordination to metal ions, (iv) MOF encapsulation in polymers, and (v) other strategies. A critical comparison and discussion of the effectiveness of polymer/MOF nanocomposites regarding their synthesis methods and their structural characteristics is presented.

scholarly journals Validating Metal-Organic Framework Nanoparticles for Their Nanosafety in Diverse Biomedical Applications

2016 ◽  
Vol 6 (2) ◽  
pp. 1600818 ◽  
Author(s):  
Stefan Wuttke ◽  
Andreas Zimpel ◽  
Thomas Bein ◽  
Simone Braig ◽  
Katharina Stoiber ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Organic Framework
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