Polymer/Metal Organic Framework (MOF) Nanocomposites for Biomedical Applications

The utilization of polymer/metal organic framework (MOF) nanocomposites in various biomedical applications has been widely studied due to their unique properties that arise from MOFs or hybrid composite systems. This review focuses on the types of polymer/MOF nanocomposites used in drug delivery and imaging applications. Initially, a comprehensive introduction to the synthesis and structure of MOFs and bio-MOFs is presented. Subsequently, the properties and the performance of polymer/MOF nanocomposites used in these applications are examined, in relation to the approach applied for their synthesis: (i) non-covalent attachment, (ii) covalent attachment, (iii) polymer coordination to metal ions, (iv) MOF encapsulation in polymers, and (v) other strategies. A critical comparison and discussion of the effectiveness of polymer/MOF nanocomposites regarding their synthesis methods and their structural characteristics is presented.

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Effect of Synthesis Methods Using Renewable PODFA on Structural Characteristics of Metal-Organic Framework (MOF-5)

IOP Conference Series Earth and Environmental Science ◽

10.1088/1755-1315/32/1/012060 ◽

2016 ◽

Vol 32 ◽

pp. 012060

Author(s):

S Z Othman ◽

H Misran ◽

W A Affendy ◽

N F Mahadi

Keyword(s):

Structural Characteristics ◽

Metal Organic Framework ◽

Synthesis Methods ◽

Metal Organic ◽

Organic Framework

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Multifunctional metal–organic framework heterostructures for enhanced cancer therapy

Chemical Society Reviews ◽

10.1039/d0cs00178c ◽

2021 ◽

Author(s):

Jintong Liu ◽

Jing Huang ◽

Lei Zhang ◽

Jianping Lei

Keyword(s):

Cancer Therapy ◽

General Principle ◽

Biomedical Applications ◽

Metal Organic Framework ◽

Metal Organic ◽

Functional Modulation ◽

Organic Framework

We review the general principle of the design and functional modulation of nanoscaled MOF heterostructures, and biomedical applications in enhanced therapy.

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Porous metal-organic framework-based filters: synthesis methods and applications for environmental remediation

Chemical Engineering Journal ◽

10.1016/j.cej.2021.133160 ◽

2021 ◽

pp. 133160

Author(s):

Huan Xiao ◽

Ze-Xian Low ◽

Damian B. Gore ◽

Ravinder Kumar ◽

Mohsen Asadnia ◽

...

Keyword(s):

Environmental Remediation ◽

Metal Organic Framework ◽

Porous Metal ◽

Synthesis Methods ◽

Metal Organic ◽

Organic Framework

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Synthesis and effect of metal–organic frame works on CO2 adsorption capacity at various pressures: A contemplating review

Energy & Environment ◽

10.1177/0958305x19865352 ◽

2019 ◽

Vol 31 (3) ◽

pp. 367-388 ◽

Cited By ~ 5

Author(s):

Ayesha Rehman ◽

Sarah Farrukh ◽

Arshad Hussain ◽

Erum Pervaiz

Keyword(s):

Adsorption Capacity ◽

Surface Area ◽

Greenhouse Gas Emission ◽

Metal Organic Framework ◽

Metal Organic Frameworks ◽

Climatic Changes ◽

Microwave Assisted Synthesis ◽

Synthesis Methods ◽

Metal Organic ◽

Organic Framework

The most important environmental challenge that the world is facing today is the control of the quantity of CO2 in the atmosphere, because it causes global warming. Increase in the global temperature results in greenhouse gas emission, interruption of the volcanic activity, and climatic changes. The alarming rise of the CO2 level impels to take some serious action to control these climatic changes. Various techniques are being utilized to capture CO2. However, chemical absorption and adsorption are supposed to be the most suitable techniques for post-combustion CO2 capture, but the main focus is on adsorption. The aim of this study is to provide a brief overview on the CO2 adsorption by a novel class of adsorbents called the metal–organic framework. The metal–organic framework is a porous material having high surface area with high CO2 adsorption capacity. The metal–organic frameworks possess dynamic structure and have large capacity to adsorb CO2 at either low pressure or high pressure due to its cavity size and surface area. Adsorption of CO2 in the metal–organic framework at various pressures depends upon pore volume and heat of adsorption correspondingly. In this review, different synthesis methods of the metal–organic framework such as slow evaporation, solvo thermal, mechanochemical, electrochemical, sonochemical, and microwave-assisted synthesis are briefly described as the structure of the metal–organic frameworks are mostly dependent upon synthesis techniques. In addition to this, different strategies are discussed to increase the CO2 adsorption capacity in the metal organic-framework. [Formula: see text]

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Guest–host interactions of nanoconfined anti-cancer drug in metal–organic framework exposed by terahertz dynamics

Chemical Communications ◽

10.1039/c8cc10089f ◽

2019 ◽

Vol 55 (27) ◽

pp. 3868-3871 ◽

Cited By ~ 8

Author(s):

Barbara E. Souza ◽

Svemir Rudić ◽

Kirill Titov ◽

Arun S. Babal ◽

James D. Taylor ◽

...

Keyword(s):

Neutron Scattering ◽

Inelastic Neutron Scattering ◽

Metal Organic Framework ◽

Inelastic Neutron ◽

Cancer Drug ◽

Host Interactions ◽

Composite Systems ◽

Anti Cancer ◽

Metal Organic ◽

Organic Framework

Guest–host interactions of mechanochemically synthesized drug@MOF composite systems revealed by inelastic neutron scattering.

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Autonomous atmospheric water seeping MOF matrix

Science Advances ◽

10.1126/sciadv.abc8605 ◽

2020 ◽

Vol 6 (42) ◽

pp. eabc8605

Author(s):

G. Yilmaz ◽

F. L. Meng ◽

W. Lu ◽

J. Abed ◽

C. K. N. Peh ◽

...

Keyword(s):

Fresh Water ◽

Metal Organic Framework ◽

Sorption Kinetics ◽

Solar Irradiation ◽

Atmospheric Water ◽

Polymer Metal ◽

Metal Organic ◽

Delivery Efficiency ◽

Organic Framework ◽

Liquid Delivery

The atmosphere contains an abundance of fresh water, but this resource has yet to be harvested efficiently. To date, passive atmospheric water sorbents have required a desorption step that relies on steady solar irradiation. Since the availability and intensity of solar radiation vary, these limit on-demand desorption and hence the amount of harvestable water. Here, we report a polymer–metal-organic framework that provides simultaneous and uninterrupted sorption and release of atmospheric water. The adaptable nature of the hydro-active polymer, and its hybridization with a metal-organic framework, enables enhanced sorption kinetics, water uptake, and spontaneous water oozing. We demonstrate continuous water delivery for 1440 hours, producing 6 g of fresh water per gram of sorbent at 90% relative humidity (RH) per day without active condensation. This leads to a total liquid delivery efficiency of 95% and an autonomous liquid delivery efficiency of 71%, the record among reported atmospheric water harvesters.

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