scholarly journals Aptamer-Modified DNA Tetrahedra-Gated Metal-Organic Framework Nanoparticle Carriers for Enhanced Chemotherapy or Photodynamic Therapy

2021 ◽  
Author(s):  
Pu Zhang ◽  
Amit Fischer ◽  
Yu Ouyang ◽  
Jianbang Wang ◽  
Sohn Yang Sung ◽  
...  

UiO-66 metal-organic framework nanoparticles (NMOFs) gated by aptamer-functionalized DNA tetrahedra provide superior biomarker-responsive hybrid nano-carriers for biomedical applications. Hybrid nano-carriers consisting of ATP-aptamer or VEGF-aptamer functionalized tetrahedra-gated NMOFs are loaded...

2021 ◽  
Author(s):  
Jintong Liu ◽  
Jing Huang ◽  
Lei Zhang ◽  
Jianping Lei

We review the general principle of the design and functional modulation of nanoscaled MOF heterostructures, and biomedical applications in enhanced therapy.


Author(s):  
Xin Yao ◽  
Xinxin Pei ◽  
Bo Li ◽  
Mengqi Lv ◽  
Wen Zhang ◽  
...  

Rational design of specific platform which can address the unavoidable side effects of traditional cancer treatments is of great interest. In this sense, herein, an intelligent nanoplatform (ZnL1@MOF-199@FA) with efficient...


2021 ◽  
Author(s):  
Xinran Sun ◽  
Kaixiu Chen ◽  
Ying-Yan Liu ◽  
Guoda Zhang ◽  
Min Shi ◽  
...  

Photodynamic therapy (PDT) has been rapidly developing an effective therapeutic approach in clinical. However, hypoxia seriously limits the effectiveness of PDT. Here, we report a porphyrinic based metal-organic framework combined...


ChemMedChem ◽  
2020 ◽  
Vol 15 (19) ◽  
pp. 1766-1775
Author(s):  
Wenmei Yu ◽  
Wenqiang Zhen ◽  
Qizhi Zhang ◽  
Yanchun Li ◽  
Hongyu Luo ◽  
...  

2019 ◽  
Vol 11 (40) ◽  
pp. 36347-36358 ◽  
Author(s):  
Qianqian Sun ◽  
Huiting Bi ◽  
Zhao Wang ◽  
Chunxia Li ◽  
Chen Wang ◽  
...  

2019 ◽  
Vol 2 (5) ◽  
pp. 2092-2101 ◽  
Author(s):  
Shalini Sharma ◽  
Disha Mittal ◽  
Anita Kamra Verma ◽  
Indrajit Roy

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