Membrane traffic during embryonic development: epithelial formation, cell fate decisions and differentiation

2004 ◽  
Vol 16 (4) ◽  
pp. 407-414 ◽  
Author(s):  
Veronica Dudu ◽  
Periklis Pantazis ◽  
Marcos González-Gaitán
Keyword(s):  
Embryonic Development ◽  
Cell Fate ◽  
Membrane Traffic ◽  
Cell Fate Decisions

Utilizing Split Fluorescent Proteins to Visualize Binary Cell Fate Decisions

2021 ◽  
Author(s):  
Setu Mehta
Keyword(s):  
Embryonic Development ◽  
Cell Fate ◽  
Protein Interactions ◽  
Fluorescent Proteins ◽  
Protein Protein Interactions ◽  
Temporal Expression ◽  
Cell Fate Decisions ◽  
Cellular Decision Making ◽  
Decision Making Processes ◽  
Intimate Knowledge

Binary cell fate decisions serve at a cornerstone of cellular decision-making processes during embryonic development. Understanding and studying these decisions require an intimate knowledge of the spatial and temporal expression dynamics of critical genes. Split fluorescent proteins (sFP) can serve as a novel tool to study these binary cell fate decisions, with unique applications such as the potential to amplify weak genetic signals. Ultimately, sFPs can be utilized to revolutionize the study of protein-protein interactions during embryonic development and beyond.

scholarly journals Mit Einzelzell-Genomik die Entscheidungen von Zellen verfolgen

BIOspektrum ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 25-27
Author(s):  
Bo Hu ◽  
Jan Philipp Junker
Keyword(s):  
Developmental Biology ◽  
Embryonic Development ◽  
Cell Fate ◽  
Cell Types ◽  
Regulatory Mechanisms ◽  
Major Question ◽  
Cell Fate Decisions ◽  
New Methods ◽  
Gene Regulatory ◽  
Different Cell Types

AbstractDuring embryonic development, cells need to take a series of successive fate decisions in order to reach their final differentiated stage. Understanding the processes that give rise to the multitude of different cell types in an organism is a major question in developmental biology. New methods in single cell genomics enable researchers to decipher the transcriptional programs and gene regulatory mechanisms that underlie cell fate decisions during embryonic development.

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