Interleukin 27 as an inducer of antiviral response against Chikungunya Virus infection in human macrophages

2021 ◽  
pp. 104411
Author(s):  
Valdés-López Juan Felipe ◽  
Geysson J. Fernandez ◽  
Urcuqui-Inchima Silvio
Keyword(s):  
Virus Infection ◽  
Chikungunya Virus ◽  
Antiviral Response ◽  
Human Macrophages ◽  
Interleukin 27

scholarly journals Chikungunya Virus Infection in Traveler to Australia

2007 ◽  
Vol 13 (3) ◽  
pp. 509-510 ◽  
Author(s):  
Julian D. Druce ◽  
Douglas F. Johnson ◽  
Thomas Tran ◽  
Michael J. Richards ◽  
Christopher J. Birch
Keyword(s):  
Virus Infection ◽  
Chikungunya Virus

scholarly journals Temperature modulates innate immunity in Aedes aegypti during chikungunya virus infection

2020 ◽  
Vol 101 ◽  
pp. 489
Author(s):  
B.R. Wimalasiri-Yapa ◽  
F. Frentiu ◽  
L. Stassen ◽  
R. Gumiel
Keyword(s):  
Innate Immunity ◽  
Virus Infection ◽  
Aedes Aegypti ◽  
Chikungunya Virus

scholarly journals Dicer is involved in protection against influenza A virus infection

2007 ◽  
Vol 88 (10) ◽  
pp. 2627-2635 ◽  
Author(s):  
Alexey A. Matskevich ◽  
Karin Moelling
Keyword(s):  
Virus Infection ◽  
Influenza A Virus ◽  
Mammalian Cells ◽  
Influenza A ◽  
Virus Production ◽  
Vero Cells ◽  
Antiviral Response ◽  
Protein Levels ◽  
Infected Cells ◽  
Influenza A Virus Infection

In mammals the interferon (IFN) system is a central innate antiviral defence mechanism, while the involvement of RNA interference (RNAi) in antiviral response against RNA viruses is uncertain. Here, we tested whether RNAi is involved in the antiviral response in mammalian cells. To investigate the role of RNAi in influenza A virus-infected cells in the absence of IFN, we used Vero cells that lack IFN-α and IFN-β genes. Our results demonstrate that knockdown of a key RNAi component, Dicer, led to a modest increase of virus production and accelerated apoptosis of influenza A virus-infected cells. These effects were much weaker in the presence of IFN. The results also show that in both Vero cells and the IFN-producing alveolar epithelial A549 cell line influenza A virus targets Dicer at mRNA and protein levels. Thus, RNAi is involved in antiviral response, and Dicer is important for protection against influenza A virus infection.

scholarly journals Kinetic Analysis of Mouse Brain Proteome Alterations Following Chikungunya Virus Infection before and after Appearance of Clinical Symptoms

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e91397 ◽  
Author(s):  
Christophe Fraisier ◽  
Penelope Koraka ◽  
Maya Belghazi ◽  
Mahfoud Bakli ◽  
Samuel Granjeaud ◽  
...  
Keyword(s):  
Virus Infection ◽  
Kinetic Analysis ◽  
Mouse Brain ◽  
Chikungunya Virus ◽  
Clinical Symptoms ◽  
Before And After ◽  
Brain Proteome

scholarly journals Chikungunya Virus Infection: First Detection of Imported and Autochthonous Cases in Panama

2015 ◽  
Vol 92 (3) ◽  
pp. 482-485 ◽  
Author(s):  
Yamilka Díaz ◽  
Ana Belén Araúz ◽  
Ana Margarita Botello ◽  
Sandra López-Vergès ◽  
Lizbeth Cerezo ◽  
...  
Keyword(s):  
Virus Infection ◽  
Chikungunya Virus

scholarly journals Long‐term survival and clinical forms in the acute phase of Chikungunya virus infection in older Caribbeans

2019 ◽  
Vol 24 (3) ◽  
pp. 363-370 ◽  
Author(s):  
Lidvine Godaert ◽  
Seendy Bartholet ◽  
Fatiha Najioullah ◽  
Hanitra Andrianasolo ◽  
Lukshe Kanagaratnam ◽  
...  
Keyword(s):  
Virus Infection ◽  
Acute Phase ◽  
Chikungunya Virus ◽  
Term Survival ◽  
Long Term Survival ◽  
Clinical Forms

scholarly journals Chikungunya virus and dengue virus coinfection: a case report from Bangladesh

2018 ◽  
Vol 12 (1) ◽  
pp. 42-43
Author(s):  
Muhammad Abdur Rahim ◽  
Shahana Zaman ◽  
Samira Rahat Afroze ◽  
Hasna Fahmima Haque ◽  
Farhana Afroz ◽  
...  
Keyword(s):  
Case Report ◽  
Virus Infection ◽  
Dengue Virus ◽  
Chikungunya Virus ◽  
Dengue Virus Infection ◽  
Emerging Infection ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up ◽  
Body Ache

A case of concurrent chikungunya virus and dengue virus infection is reported here. The patient presented with fever and generalized body ache. Diagnostic work-up revealed chikungunya-dengue co-infection. Dengue is endemic in Bangladesh while chikungunya is a recently emerging infection. As both the viruses are transmitted by a common vector, Aedes spp., such co-infections are likely to increase in coming years.IMC J Med Sci 2018; 12(1): 42-43

scholarly journals Complete Coding Sequence of a Case of Chikungunya Virus Imported into Australia

2017 ◽  
Vol 5 (19) ◽  
Author(s):  
Bixing Huang ◽  
Alyssa T. Pyke ◽  
Jamie McMahon ◽  
David Warrilow
Keyword(s):  
Phylogenetic Analysis ◽  
Virus Infection ◽  
Real Time ◽  
South African ◽  
Genome Sequencing ◽  
Reverse Transcription ◽  
Chikungunya Virus ◽  
East Central ◽  
Reverse Transcription Pcr ◽  
Central South

ABSTRACT A case of chikungunya virus infection was imported from India into Australia in late 2016. Infection was diagnosed by real-time reverse transcription-PCR and confirmed by culture isolation and genome sequencing. Phylogenetic analysis of the genome sequence indicated that the virus grouped with the east/central/south African genotype.

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