CXCL10 expression induced by Mxi1 inactivation induces mesangial cell apoptosis in mouse Habu nephritis

2015 ◽  
Vol 27 (5) ◽  
pp. 943-950 ◽  
Author(s):  
Lingling Wu ◽  
Xiaoniao Chen ◽  
Yan Mei ◽  
Quan Hong ◽  
Zhe Feng ◽  
...  
Keyword(s):  
Cell Apoptosis ◽  
Mesangial Cell

scholarly journals High Glucose Induces Mesangial Cell Apoptosis through miR-15b-5p and Promotes Diabetic Nephropathy by Extracellular Vesicle Delivery

2020 ◽  
Vol 28 (3) ◽  
pp. 963-974 ◽  
Author(s):  
Yi-Chun Tsai ◽  
Mei-Chuan Kuo ◽  
Wei-Wen Hung ◽  
Ling-Yu Wu ◽  
Ping-Hsun Wu ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
High Glucose ◽  
Cell Apoptosis ◽  
Mesangial Cell ◽  
Extracellular Vesicle

scholarly journals Sublytic C5b-9 Induces Glomerular Mesangial Cell Apoptosis through the Cascade Pathway of MEKK2–p38 MAPK–IRF-1–TRADD–Caspase 8 in Rat Thy-1 Nephritis

2016 ◽  
Vol 198 (3) ◽  
pp. 1104-1118 ◽  
Author(s):  
Ganqian Zhu ◽  
Wen Qiu ◽  
Yongting Li ◽  
Chenhui Zhao ◽  
Fengxia He ◽  
...  
Keyword(s):  
P38 Mapk ◽  
Cell Apoptosis ◽  
Mesangial Cell ◽  
Caspase 8 ◽  
Glomerular Mesangial Cell

The Actions of C-Type Natriuretic Peptide on Human Mesangial Cell Apoptosis and P53 Expression

2000 ◽  
Vol 6 (S2) ◽  
pp. 624-625
Author(s):  
K. Seta ◽  
C. Wei
Keyword(s):  
Receptor Antagonist ◽  
Natriuretic Peptide ◽  
Cell Apoptosis ◽  
Mesangial Cell ◽  
Mesangial Cells ◽  
Endocrine System ◽  
P53 Gene ◽  
Glomerular Mesangial Cells ◽  
P53 Expression ◽  
Human Mesangial Cell

C-type natriuretic peptide (CNP) of endothelial cell origin via NPR-B receptor mediates antimitogenic and vasodilatory actions. As a circulating endocrine system, CNP plays a fundamental role in cardiorenal regulation. However, the actions of CNP on renal mesangial cell apoptosis remain poorly defined. Apoptosis might plays an important role during development of renal glomerular mesangial cells pathophysiology. The mechanisms of apoptosis include p53-dependent pathway and p53-independent pathway.The hypothesis of this study is that CNP induces apoptosis through the process involving p53 gene in human glomerular mesangial cells via natriuretic peptide biological receptor. Therefore, the current study was designed to investigate the effects of CNP on apoptosis and p53 expression in human mesangial cell in the absence or presence of CNP biological receptor antagonist.Cultured human mesangial cells (Clontech Lab., San Diego, CA) was incubated for 24 hours in the absence or presence of CNP (10-7 M). These studies were repeated with HS 142-1 (HS, 10-5 M), a CNP biological receptor antagonist.

scholarly journals Angiotensin II-Induced Mesangial Cell Apoptosis: Role of Oxidative Stress

2002 ◽  
Vol 8 (12) ◽  
pp. 830-840 ◽  
Author(s):  
Saurabh Lodha ◽  
Dhimant Dani ◽  
Rajeev Mehta ◽  
Madhu Bhaskaran ◽  
Krishna Reddy ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Angiotensin Ii ◽  
Cell Apoptosis ◽  
Mesangial Cell

scholarly journals Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy

2018 ◽  
Vol 13 ◽  
pp. 543-555 ◽  
Author(s):  
Yi-Chun Tsai ◽  
Po-Lin Kuo ◽  
Wei-Wen Hung ◽  
Ling-Yu Wu ◽  
Ping-Hsun Wu ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Cell Apoptosis ◽  
Mesangial Cell

scholarly journals Native and oxidized low density lipoproteins modulate mesangial cell apoptosis

1996 ◽  
Vol 50 (5) ◽  
pp. 1604-1611 ◽  
Author(s):  
Pratima Sharma ◽  
Krishna Reddy ◽  
Nicholas Franki ◽  
Vibha Sanwal ◽  
Ramkumar Sankaran ◽  
...  
Keyword(s):  
Cell Apoptosis ◽  
Mesangial Cell ◽  
Low Density Lipoproteins ◽  
Low Density ◽  
Oxidized Low Density Lipoproteins
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