Enhancement of mechanical strength and osteogenesis, and inhibition of osteoclastic activity for β-tricalcium phosphate bioceramics by incorporating calcium silicate and magnesium-strontium phosphate

2021 ◽  
Author(s):  
Songheng Feng ◽  
Fupo He ◽  
Xibo Fang ◽  
Xin Deng ◽  
Teliang Lu ◽  
...  
Keyword(s):  
Mechanical Strength ◽  
Tricalcium Phosphate ◽  
Calcium Silicate ◽  
Osteoclastic Activity ◽  
Strontium Phosphate

Conjunction of gallium doping and calcium silicate mediates osteoblastic and osteoclastic performances of tricalcium phosphate bioceramics

2021 ◽  
Author(s):  
Fupo He ◽  
Chao Qiu ◽  
Teliang Lu ◽  
Xuetao Shi ◽  
Jiandong Ye
Keyword(s):  
Mechanical Strength ◽  
Tricalcium Phosphate ◽  
Calcium Silicate ◽  
Bone Defects ◽  
Osteoporotic Bone ◽  
Densification Process ◽  
Potent Effect ◽  
Inhibition Effect ◽  
Gallium Doping

Abstract Gallium-containing biomaterials are considered promising for reconstructing osteoporotic bone defects, owing to the potent effect of gallium on restraining osteoclast activities. Nevertheless, the gallium-containing biomaterials were demonstrated to disturb the osteoblast activities. In this study, tricalcium phosphate (TCP) bioceramics were modified by gallium doping in conjunction with incorporation of calcium silicate (CS). The results indicated that the incorporation of CS promoted transition of β-TCP to α-TCP, and accelerated densification process, but did not improve the mechanical strength of bioceramics. The silicon released from the composite bioceramics diminished the inhibition effect of released gallium on osteoblast activities, and maintained its effect on restraining osteoclast activities. The TCP-based bioceramics doped with 2.5 mol% gallium and incorporated with 10 mol% CS are considered suitable for treating the bone defects in the osteoporotic environment.

Mechanical strength characterization and modeling of hydroxyapatite/tricalcium phosphate biocomposite using the diametral-compression test

2021 ◽  
Vol 93 (3) ◽  
pp. 30403
Author(s):  
Mohammed Es-Saddik ◽  
Said Laasri ◽  
Abdelaziz Laghzizil ◽  
Jean-Michel Nunzi ◽  
Mohammed Taha ◽  
...  
Keyword(s):  
Mechanical Strength ◽  
Tricalcium Phosphate ◽  
Sintering Temperature ◽  
Rupture Strength ◽  
Mechanical Resistance ◽  
The Finite Element Method ◽  
Maximum Value ◽  
Strength Characterization ◽  
Powder Manufacturing ◽  
Diametral Compression Test

This study reports the enhanced mechanical resistance of the composite bioceramics of hydroxyapatite (HAP) and tricalcium phosphate (β-TCP) used as bone substitute. HAP/β-TCP mixture was prepared by wet mixing of powders and characterized. Effects of powder manufacturing and sintering temperature on the densification, microstructure and mechanical properties of the composite were studied. The rupture strength (σr) was calculated using the Brazilian test. At 1250 °C, the relative density and mechanical strength of the HAP/β-TCP ceramics reached the maximum value of 89% and 43 MPa, respectively. Experimental results were modeled by the finite element method to determine the stress distribution in the compacted disc.

scholarly journals Effect of Mixed Addition of Al2O3 and SiO2 on Mechanical Strength of Sintered β-Tricalcium Phosphate

1988 ◽  
Vol 96 (1116) ◽  
pp. 837-841 ◽  
Author(s):  
Motohiro TORIYAMA ◽  
Sukezo KAWAMURA ◽  
Yukari ITO ◽  
Hajime NAGAE ◽  
Ikuo TOYAMA
Keyword(s):  
Mechanical Strength ◽  
Tricalcium Phosphate

Influences of gallium substitution on the phase stability, mechanical strength and cellular response of β-tricalcium phosphate bioceramics

2020 ◽  
Vol 46 (10) ◽  
pp. 16364-16371
Author(s):  
Chao Qiu ◽  
Teliang Lu ◽  
Fupo He ◽  
Songheng Feng ◽  
Xibo Fang ◽  
...  
Keyword(s):  
Mechanical Strength ◽  
Phase Stability ◽  
Tricalcium Phosphate ◽  
Cellular Response

Wollastonite as a Flux for Ceramics Bodies

2012 ◽  
Vol 727-728 ◽  
pp. 1016-1021 ◽  
Author(s):  
S.R. Bragança ◽  
H.C.M Lengler ◽  
Carlos Pérez Bergmann
Keyword(s):  
Mechanical Strength ◽  
Mechanism Of Action ◽  
Calcium Silicate ◽  
Raw Materials ◽  
Alkali Feldspar ◽  
Temperature Phase ◽  
Technological Properties ◽  
Silicate Mineral ◽  
Technical Properties ◽  
Ceramic Flux

Wollastonite is a calcium silicate mineral natural or synthetic. Commercial wollastonite starts to melt at about 1450°C and can not be considered a "flux" as alkali feldspar. For this function, it depends on the reaction with other raw materials. Faced with this, came the goal of this work which was to investigate the mechanism of action of wollastonite as a ceramic flux. The use of wollastonite in ceramic bodies was investigated by analysis of its reactivity with other materials such as quartz, kaolin, talc and feldspar. It was analyzed the technological properties of the final parts, especially in relation to the firing temperature, phase formation and technological properties (mechanical strength, porosity, etc.). The results of this characterization showed that the technical properties of the parts are developed according to commercial porcelain products.

Effects of chitosan and zirconia on setting time, mechanical strength, and bioactivity of calcium silicate-based cement

2016 ◽  
Vol 14 (2) ◽  
pp. 135-144 ◽  
Author(s):  
Ali Kamali ◽  
Sirus Javadpour ◽  
Bahar Javid ◽  
Niloofar Kianvash Rad ◽  
Sina Naddaf Dezfuli
Keyword(s):  
Mechanical Strength ◽  
Calcium Silicate ◽  
Setting Time

Substantial enhancement of corrosion resistance and bioactivity of magnesium by incorporating calcium silicate particles

RSC Advances ◽  
2016 ◽  
Vol 6 (53) ◽  
pp. 47897-47906 ◽  
Author(s):  
Zhiguang Huan ◽  
Chen Xu ◽  
Bing Ma ◽  
Jie Zhou ◽  
Jiang Chang
Keyword(s):  
Corrosion Resistance ◽  
Mechanical Strength ◽  
Calcium Silicate ◽  
Orthopedic Implant ◽  
Biological Performance ◽  
Effective Reinforcement

We discovered that calcium silicate is an effective reinforcement phase to improve the corrosion resistance, mechanical strength and biological performance of Mg or Mg-based alloys to overcome their major drawbacks for orthopedic implant applications.

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