Elimination study of the chemotherapy drug tamoxifen by different advanced oxidation processes: Transformation products and toxicity assessment

The application of Fenton-based advanced oxidation processes (AOPs), such as photo-Fenton or electro-Fenton for wastewater treatment have been extensively studied in recent decades due to its high efficiency for the decomposition of persistent organic pollutants. Usually Fenton-based AOPs are used for the degradation of targeted pollutant or group of pollutants, which often leads to the formation of toxic by-products possessing a potential environmental risk. In this work, we have collected and reviewed recent findings regarding the feasibility of Fenton-based AOPs (photo-Fenton, UVC/H2O2, electro-Fenton and galvanic Fenton) for the detoxification of real municipal and industrial wastewaters. More specifically, operational conditions, relevance and suitability of different bioassays for the toxicity assessment of various wastewater types, cost estimation, all of which compose current challenges for the application of these AOPs for real wastewater detoxification are discussed.

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Degradation of Carbamazepine by Photo(electro)catalysis on Nanostructured TiO2 Meshes: Transformation Products and Reaction Pathways

Catalysts ◽

10.3390/catal10020169 ◽

2020 ◽

Vol 10 (2) ◽

pp. 169 ◽

Cited By ~ 6

Author(s):

Silvia Franz ◽

Ermelinda Falletta ◽

Hamed Arab ◽

Sapia Murgolo ◽

Massimiliano Bestetti ◽

...

Keyword(s):

Plasma Electrolytic Oxidation ◽

Advanced Oxidation Processes ◽

Scale Up ◽

Advanced Oxidation ◽

Transformation Products ◽

Reaction Pathways ◽

Oxidation Processes ◽

Electro Catalysis ◽

Electrolytic Oxidation ◽

Plasma Electrolytic

Carbamazepine (CBZ) is a pharmaceutical compound recalcitrant to conventional wastewater treatment plants and widely detected in wastewater bodies. In the present study, advanced oxidation processes for carbamazepine removal are investigated, with particular regard to the degradation pathways of carbamazepine by photoelectrocatalysis and conventional photocatalysis. Photoelectrocatalysis was carried out onto TiO2 meshes obtained by Plasma Electrolytic Oxidation, a well-known technique in the field of industrial surface treatments, in view of an easy scale-up of the process. By photoelectrocatalysis, 99% of carbamazepine was removed in 55 min while only 65% removal was achieved by photolysis. The investigation of the transformation products (TPs) was carried out by means of UPLC-QTOF/MS/MS. Several new TPs were identified and accordingly reaction pathways were proposed. Above 80 min the transformation products disappear, probably forming organic acids of low-molecular weight as final degradation products. The results demonstrated that photoelectrocatalysis onto TiO2 meshes obtained by plasma electrolytic oxidation is a useful alternative to common advanced oxidation processes as wastewater tertiary treatment aimed at removing compounds of emerging concern.

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Application of Liquid Chromatography-Mass Spectrometry for the Analysis of Endocrine Disrupting Chemical Transformation Products in Advanced Oxidation Processes and Their Reaction Mechanisms

Handbook of Environmental Materials Management ◽

10.1007/978-3-319-73645-7_90 ◽

2019 ◽

pp. 1633-1657

Author(s):

Jin-Chung Sin ◽

Sze-Mun Lam ◽

Abdul Rahman Mohamed

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Chemical Transformation ◽

Reaction Mechanisms ◽

Advanced Oxidation Processes ◽

Advanced Oxidation ◽

Transformation Products ◽

Endocrine Disrupting Chemical ◽

Oxidation Processes ◽

Endocrine Disrupting

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Transformation products and mechanistic pathway of levofloxacin degradation in aqueous solution using advanced oxidation processes in the presence of BiVO4 and visible light

10.5004/dwt.2020.25124 ◽

2020 ◽

Vol 183 ◽

pp. 325-334

Author(s):

Mohammed A. Meetani ◽

Ahmed Alzamly ◽

Naji Al-Dubaili ◽

Mohamed F. Malik ◽

Nada Elmerhi ◽

...

Keyword(s):

Aqueous Solution ◽

Visible Light ◽

Advanced Oxidation Processes ◽

Advanced Oxidation ◽

Transformation Products ◽

Oxidation Processes ◽

Mechanistic Pathway

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Chemical and toxicological evaluation of transformation products during advanced oxidation processes

Water Science & Technology ◽

10.2166/wst.2013.452 ◽

2013 ◽

Vol 68 (9) ◽

pp. 1976-1983 ◽

Cited By ~ 8

Author(s):

C. vom Eyser ◽

A. Börgers ◽

J. Richard ◽

E. Dopp ◽

N. Janzen ◽

...

Keyword(s):

Advanced Oxidation Processes ◽

Waste Water Treatment ◽

Treatment Plant ◽

Advanced Oxidation ◽

Transformation Products ◽

Product Formation ◽

Toxicological Evaluation ◽

H2o2 Treatment ◽

Oxidation Processes ◽

Estrogenic Potential

The entry of pharmaceuticals into the water cycle from sewage treatment plants is of growing concern because environmental effects are evident at trace levels. Ozonation, UV- and UV/H2O2-treatment were tested as an additional step in waste water treatment because they have been proven to be effective in eliminating aqueous organic contaminants. The pharmaceuticals carbamazepine, ciprofloxacin, diclofenac, metoprolol and sulfamethoxazole as well as the personal care products galaxolide and tonalide were investigated in terms of degradation efficiency and by-product formation in consideration of toxic effects. The substances were largely removed from treatment plant effluent by ozonation, UV- and UV/H2O2-treatment. Transformation products were detected in all tested treatment processes. Accompanying analysis showed no genotoxic, cytotoxic or estrogenic potential for the investigated compounds after oxidative treatment of real waste waters. The results indicate that by-product formation from ozonation and advanced oxidation processes does not have any negative environmental impact.

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