Fast separation of antiviral nucleoside phosphoramidate and H-phosphonate diastereoisomers by reversed-phase liquid chromatography

2011 ◽  
Vol 1218 (10) ◽  
pp. 1416-1422 ◽  
Author(s):  
Xiang Gao ◽  
Weizhu Chen ◽  
Gangtian Zhu ◽  
Ruizao Yi ◽  
Zhen Wu ◽  
...  
Author(s):  
Ling DING ◽  
Jun DONG ◽  
Yuan-Sheng XIAO ◽  
Xiu-Li ZHANG ◽  
Xing-Ya XUE ◽  
...  

2015 ◽  
Vol 2 (2) ◽  
pp. 110-121 ◽  
Author(s):  
Tamara Alvarez-Segura ◽  
María García-Alvarez-Coque ◽  
Casandra Ortiz-Bolsico ◽  
José Torres-Lapasió

1984 ◽  
Vol 49 (8) ◽  
pp. 1921-1926 ◽  
Author(s):  
Michal Lebl ◽  
Tomislav Barth ◽  
Denis J. Crankshaw ◽  
Bohuslav Černý ◽  
Edwin E. Daniel ◽  
...  

The title compound (specific activity 11.1-32.7 Ci (0.41-1.22 TBq)/mmol) was prepared by iodination and subsequent catalytic replacement of iodine by tritium. The analogue which was unstable in the form of a lyophilizate was purified by reversed phase liquid chromatography. Using the N,N'-dicyclohexylcarbodiimide method, the pure analogue was converted into N-hydroxybenzotriazolyl ester, an irreversible oxytocin inhibitor. However, attempts to label specifically the uterotonic receptor, present in the enriched rat myometrium fraction, were hithero unsuccessful


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