Synthesis and properties of [2-[3,5-3H2]-tyrosine,4-glutamic acid]deamino-1-carba-oxytocin
1984 ◽
Vol 49
(8)
◽
pp. 1921-1926
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Keyword(s):
The title compound (specific activity 11.1-32.7 Ci (0.41-1.22 TBq)/mmol) was prepared by iodination and subsequent catalytic replacement of iodine by tritium. The analogue which was unstable in the form of a lyophilizate was purified by reversed phase liquid chromatography. Using the N,N'-dicyclohexylcarbodiimide method, the pure analogue was converted into N-hydroxybenzotriazolyl ester, an irreversible oxytocin inhibitor. However, attempts to label specifically the uterotonic receptor, present in the enriched rat myometrium fraction, were hithero unsuccessful
1983 ◽
Vol 43
(6)
◽
pp. 463-472
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2013 ◽
Vol 41
(2)
◽
pp. 181
2017 ◽
Vol 35
(10)
◽
pp. 1042
◽
2016 ◽
Vol 34
(7)
◽
pp. 726
◽
Interpretive Approaches to Optimize Serially-Coupled Columns in Reversed-Phase Liquid Chromatography
2015 ◽
Vol 2
(2)
◽
pp. 110-121
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2015 ◽
Vol 2
(2)
◽
pp. 136-144
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1983 ◽
Vol 48
(11)
◽
pp. 3279-3286