Development of a novel comprehensive analytical method for volatile compounds using supercritical fluid chromatography/mass spectrometry with a highly cross-linked styrene divinylbenzene polymer-based column

2020 ◽  
Vol 1626 ◽  
pp. 461363
Author(s):  
Yuka Fujito ◽  
Yoshihiro Hayakawa ◽  
Takeshi Bamba
Keyword(s):  
Mass Spectrometry ◽  
Volatile Compounds ◽  
Supercritical Fluid ◽  
Supercritical Fluid Chromatography ◽  
Analytical Method ◽  
Chromatography Mass Spectrometry ◽  
Styrene Divinylbenzene

Simultaneous identification and determination of eleven tyrosine kinase inhibitors by supercritical fluid chromatography-mass spectrometry

2019 ◽  
Vol 11 (16) ◽  
pp. 2211-2222
Author(s):  
Shaomin Zhang ◽  
Wei Jin ◽  
Yongjian Yang
Keyword(s):  
Mass Spectrometry ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Supercritical Fluid ◽  
Supercritical Fluid Chromatography ◽  
Analytical Method ◽  
Kinase Inhibitors ◽  
Chromatography Mass Spectrometry ◽  
Simultaneous Identification

A rapid analytical method using supercritical fluid chromatography (SFC) coupled to mass spectrometry for the simultaneous identification and determination of eleven tyrosine kinase inhibitors (TKIs) was developed and validated.

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