Influence of Simultaneous Liver and Peritoneal Resection on Postoperative Morbi-Mortality and Survival in Patients With Colon Cancer Treated With Surgical Cytoreduction and Intraperitoneal Hyperthermic Chemotherapy

2017 ◽  
Vol 95 (4) ◽  
pp. 214-221
Author(s):  
Rafael Morales Soriano ◽  
José Miguel Morón Canis ◽  
Xavier Molina Romero ◽  
Judit Pérez Celada ◽  
Silvia Tejada Gavela ◽  
...  
1998 ◽  
Vol 84 (4) ◽  
pp. 483-488 ◽  
Author(s):  
Federico Bozzetti ◽  
Maurizio Vaglini ◽  
Marcello Deraco

There is preliminary evidence from experience in the treatment of various abdominal malignancies that intraperitoneal chemotherapy alone or combined with hyperthermia may attain a role in the therapeutic strategy. This paper considers the rationale for such an approach, as well as its current results and potential indications in patients with gastric cancer. The literature is critically reviewed, with special emphasis on specific topics such as patterns of tumor spread, mechanisms of local recurrence, the rationale for intraperitoneal chemotherapy and intraperitoneal hyperthermic chemotherapy, toxicity, and results from non-controlled as well as randomized clinical trials in patients with gastric cancer. There is some evidence that intraperitoneal hyperthermic chemotherapy has a favorable effect on clinical outcome in patients with limited peritoneal carcinomatosis or malignant ascitis and in those at risk of future peritoneal spread, such as patients with pT3-pT4 cancers or with positive cytology of the peritoneal fluid. Hyperthermic chemotherapy should be considered a promising approach in limited or impending peritoneal carcinomatosis, and should be included in the multidisciplinary approach to the treatment of locally advanced gastric cancer.


2013 ◽  
Vol 7 (2) ◽  
pp. 88-92 ◽  
Author(s):  
S M Kamal ◽  
Md Abu Bakar ◽  
Md Yusuf Ali ◽  
Md Abdul Ahad

Pseudomyxoma peritonei (PMP) is rare clinical entity characterized by abundant extracellular mucinous material in the peritoneal cavity and tumoural implants on the peritoneal surfaces. The origin of PMP is controversial. It often arises from the goblet cells of large bowel or appendix. There is increase in MUC-2 secreting cells and accumulation of excessive mucin secreted by these cells in the peritoneal cavity. A ruptured appendiceal mucinous adenoma is the most common origin. Low grade ovarian malignancy is often associated. Patient may present with growing abdominal masses associated with abdominal pain, nausea, vomiting, fatigue and weight loss. Ultrasonogram and CT scan of the abdomen have role in diagnosis but diagnosis is often difficult before laparotomy or laparoscopy. Debulking surgery with intraperitoneal hyperthermic chemotherapy is the treatment. DOI: http://dx.doi.org/10.3329/fmcj.v7i2.13523 Faridpur Med. Coll. J. 2012;7(2):88-92


2007 ◽  
Vol 106 (1) ◽  
pp. 193-200 ◽  
Author(s):  
Jeong Hoon Bae ◽  
Joon Mo Lee ◽  
Ki Sung Ryu ◽  
Yong Seok Lee ◽  
Yong Gyu Park ◽  
...  

2021 ◽  
Author(s):  
MingKun Sun ◽  
Xiaohua Niu ◽  
Ying Tang ◽  
Wenzhong Mo ◽  
Haiyang Xin ◽  
...  

Abstract Background: Appendiceal malignant tumors are rare in the clinic, and the incidence rate of gastrointestinal tumors is only approximately 0.5%. Our aim is to describe our experience with this rare disease and to increase knowledge on the diagnosis and treatment of appendiceal malignant tumors. Case presentation: We report the case of a 69-year-old woman who was admitted to the hospital due to dyspepsia. The patient was a carrier of hepatitis B virus, and liver dysfunction was diagnosed preoperatively. Abdominal enhanced computed tomography and colonoscopy showed that the appendix was significantly enlarged and dilated, and effusion and appendicitis were observed. Mucinous adenocarcinoma and appendiceal abscesses were not excluded because of the lack of specificity, which makes it difficult to diagnose the disease before a surgery. Laparoscopic appendectomy was performed, and a rapid frozen pathological examination showed a mucinous tumor of the appendix. Intraperitoneal hyperthermic chemotherapy with cisplatin was administered. The patient had abdominal hemorrhage on the fifth day after the surgery. After active treatment, she was discharged from the hospital 19 days after the surgery.Conclusions: The diagnosis of appendiceal malignant tumors mainly depends on preoperative imaging and microscopic results,and highly suspected patients, rapid pathological examination is needed during the operation., and so on. Notably, for elderly patients with hepatitis B infection and liver dysfunction, there is a probability of postoperative bleeding.


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