The safety and efficacy of the Neuroform EZ stent for the treatment of symptomatic atherosclerotic stenosis in the middle cerebral artery

2022 ◽  
Vol 82 ◽  
pp. 210-215
Author(s):  
Hui Li ◽  
Lei Zhang ◽  
Peng Wang ◽  
Chaolai Liu ◽  
Yafei Zhou ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Safety And Efficacy ◽  
Atherosclerotic Stenosis

Compensatory remodeling in symptomatic middle cerebral artery atherosclerotic stenosis: a high-resolution MRI and microemboli monitoring study

2012 ◽  
Vol 34 (2) ◽  
pp. 153-158 ◽  
Author(s):  
Ming-Chao Shi ◽  
Shou-Chun Wang ◽  
Hong-Wei Zhou ◽  
Ying-Qi Xing ◽  
Yan-Hua Cheng ◽  
...  
Keyword(s):  
High Resolution ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Atherosclerotic Stenosis ◽  
High Resolution Mri ◽  
Monitoring Study

scholarly journals Perfusion and plaque evaluation to predict recurrent stroke in symptomatic middle cerebral artery stenosis

2019 ◽  
Vol 4 (3) ◽  
pp. 129-134 ◽  
Author(s):  
Jinhao Lyu ◽  
Ning Ma ◽  
Chenglin Tian ◽  
Feng Xu ◽  
Hang Shao ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Recurrent Stroke ◽  
Multivariable Analysis ◽  
Volume Ratio ◽  
Plaque Burden ◽  
Atherosclerotic Stenosis ◽  
Imaging Characteristics ◽  
Significant Difference ◽  
Lumen Narrowing

Background and purposeWe investigated the baseline demographics of patients with severe unilateral atherosclerotic stenosis of the middle cerebral artery (MCA) using multimodal MRI and evaluated the haemodynamic impairments and plaque characteristics of patients who had a recurrent stroke.Materials and methodsWe retrospectively recruited consecutive patients with severe unilateral atherosclerotic MCA stenosis who underwent arterial spin labelling (ASL) with postlabelling delay (PLD) of 1.5 and 2.5 s, and vessel wall MRI. For each PLD, cerebral blood flow (CBF) maps were generated. Hypoperfusion volume ratio (HVR) from 2 PLD CBF was calculated. An HVR value ≥50% was considered as severe HVR. Plaque areas, plaque burden, plaque length and remodelling index were measured. Plaque enhancement at maximal lumen narrowing site were graded. Baseline clinical and imaging characteristics were compared between patients with (event+) and without (event−) 1 year ischaemic events.ResultsForty-three patients (47.23±12.15 years; 28 men) were enrolled in this study. Seven patients had an HVR ≥50%. During the 1-year follow-up, 7 patients had experienced a recurrent stroke. HVR were significantly higher in the event+ than event− (53.17%±29.82% vs 16.9%±15.57%, p=0.0002), whereas no significant difference was detected in plaque areas, plaque burden, remodelling index, plaque length and plaque enhancement grade. The multivariable analysis revealed that a severe HVR was significantly associated with a recurrent stroke (Odds ratio=12.93, 95% confidence interval 1.57 to 106.24, p=0.017) after adjusted by hypertension and smoking.ConclusionHVR obtained from two PLD ASL may be a useful imaging predictor of recurrent stroke.

scholarly journals r-tPA with loading dose of clopidogrel and aspirin therapies for capsular warning syndrome attributed to middle cerebral artery atherosclerotic stenosis

Medicine ◽  
2020 ◽  
Vol 99 (9) ◽  
pp. e19247
Author(s):  
Jinghan Xu ◽  
Meiting Zhuang ◽  
Guanshui Bao ◽  
Yu Zhai ◽  
Guo-Yuan Yang ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Loading Dose ◽  
Atherosclerotic Stenosis ◽  
Capsular Warning Syndrome

Safety and Efficacy of Ultrasound-enhanced Thrombolysis in the Treatment of Acute Middle Cerebral Artery Infarction

2011 ◽  
Vol 17 (6) ◽  
pp. 346-351 ◽  
Author(s):  
Christopher Kramer ◽  
Maria I. Aguilar ◽  
Charlene Hoffman-Snyder ◽  
Kay E. Wellik ◽  
Dean M. Wingerchuk ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Middle Cerebral Artery Infarction ◽  
Safety And Efficacy

Endoluminal flow diverting stents for middle cerebral artery bifurcation aneurysms: multicenter cohort

2021 ◽  
pp. neurintsurg-2021-018224
Author(s):  
Mohamed M Salem ◽  
Mirhojjat Khorasanizadeh ◽  
Sovann V Lay ◽  
Leonardo Renieri ◽  
Anna L Kuhn ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Safety And Efficacy ◽  
Complete Occlusion ◽  
Maximal Diameter ◽  
Increased Risk ◽  
Ischemic Complications ◽  
Male Sex ◽  
Radiographic Data

BackgroundData regarding the safety and efficacy of flow diverting stents (FDS) in the treatment of middle cerebral artery (MCA) bifurcation aneurysms are scarce and limited to small single center series, with particular concern for increased risk of ischemic complications with jailing one of the M2 branches.MethodsProspectively-maintained databases at six North American and European centers were queried for patients harboring MCA bifurcation aneurysms undergoing treatment with FDS (2011–2018). The pertinent clinical and radiographic data were collected and analyzed.Results87 patients (median age 60 years, 69% females) harboring 87 aneurysms were included. The majority of aneurysms were unruptured (79%); 75.9% were saccular with a median maximal diameter of 8.5 mm. Radiographic imaging follow-up was available in 88.5% of cases at a median of 16.3 months post-treatment, showing complete occlusion in 59% and near complete occlusion (90–99%) in 18% of aneurysms. The overall rate of ischemic and hemorrhagic complications was 8% and 1.1%, respectively. Symptomatic and permanent complications were encountered in 5.7% and 2.3% of patients respectively, with retreatment pursued in 2.3% of patients. Jailed branch occlusion was detected in 11.5% of cases, with clinical sequelae in 2.3%. Last follow-up modified Rankin Scale of 0–2 was noted in 96.8% of patients. On multivariate analysis, male sex was the only independent predictor of aneurysmal persistence at last follow-up imaging (p=0.019).ConclusionFDS treatment for MCA bifurcation aneurysms is feasible, with comparable safety and efficacy profiles to other available endovascular options when utilized in carefully selected aneurysms. Jailing of M2 branches was not associated with a higher risk of post-procedural ischemic complications.

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