HLA Antigens as Risk Factors for Acute and Chronic Graft Versus Host Disease in Allogenic Stem Cell Transplant – A Single Centre Experience from India

2018 ◽  
Vol 18 ◽  
pp. S307
Author(s):  
Sachin Punatar ◽  
Avinash Bonda ◽  
Anant Gokarn ◽  
Lingaraj Nayak ◽  
Aniket Mohite ◽  
...  
Keyword(s):  
Risk Factors ◽  
Stem Cell ◽  
Graft Versus Host Disease ◽  
Stem Cell Transplant ◽  
Hla Antigens ◽  
Cell Transplant ◽  
Single Centre ◽  
Graft Versus Host ◽  
Single Centre Experience ◽  
Allogenic Stem Cell Transplant

scholarly journals A Novel Secondary Neoplasm Following Allogeneic Hematopoietic Stem Cell Transplant: Mixed Donor-Recipient Primitive Mesenchymal Proliferation of the Liver

2021 ◽  
pp. 109352662110016
Author(s):  
Brian Earl ◽  
Zi Fan Yang ◽  
Harini Rao ◽  
Grace Cheng ◽  
Donna Wall ◽  
...  
Keyword(s):  
Stem Cell ◽  
Hematopoietic Stem Cell ◽  
Graft Versus Host Disease ◽  
Hematopoietic Stem Cell Transplant ◽  
Stem Cell Transplant ◽  
Cell Transplant ◽  
Hematopoietic Stem ◽  
Host Disease ◽  
Graft Versus Host ◽  
Post Transplant

Post-hematopoietic stem cell transplant secondary solid neoplasms are uncommon and usually host-derived. We describe a 6-year-old female who developed a mixed donor-recipient origin mesenchymal stromal tumor-like lesion in the liver following an unrelated hematopoietic stem cell transplant complicated by severe graft-versus-host disease. This lesion arose early post-transplant in association with hepatic graft-versus-host disease. At 12 years post-transplant, the neoplasm has progressively shrunken in size and the patient remains well with no neoplasm-associated sequelae. This report characterizes a novel lesion of mixed origin post-transplant and offers unique insights into the contribution of bone marrow-derived cells to extra-medullary tissues.

Sign in / Sign up

Export Citation Format

Share Document