Resting energy expenditure and fat-free mass do not decline during aging in severely obese women

2008 ◽  
Vol 27 (4) ◽  
pp. 657-659 ◽  
Author(s):  
M. Monda ◽  
G. Messina ◽  
C. Mangoni ◽  
B. De Luca
Keyword(s):  
Energy Expenditure ◽  
Resting Energy Expenditure ◽  
Fat Free Mass ◽  
Obese Women ◽  
Severely Obese ◽  
Resting Energy

Resting Energy Expenditure in Obese Women with Primary Hypothyroidism and Appropriate Levothyroxine Replacement Therapy

2020 ◽  
Vol 105 (4) ◽  
pp. e1741-e1748 ◽  
Author(s):  
Emanuele Muraca ◽  
Stefano Ciardullo ◽  
Alice Oltolini ◽  
Francesca Zerbini ◽  
Eleonora Bianconi ◽  
...  
Keyword(s):  
Body Composition ◽  
Energy Expenditure ◽  
Replacement Therapy ◽  
Resting Energy Expenditure ◽  
Primary Hypothyroidism ◽  
Normal Serum ◽  
Fat Free Mass ◽  
Model Assessment ◽  
Obese Women ◽  
Resting Energy

Abstract Context Growing evidence suggests that appropriate levothyroxine (LT4) replacement therapy may not correct the full set of metabolic defects afflicting individuals with hypothyroidism. Objective To assess whether obese subjects with primary hypothyroidism are characterized by alterations of the resting energy expenditure (REE). Design Retrospective analysis of a set of data about obese women attending the outpatients service of a single obesity center from January 2013 to July 2019. Patients A total of 649 nondiabetic women with body mass index (BMI) > 30 kg/m2 and thyrotropin (TSH) level 0.4–4.0 mU/L were segregated into 2 groups: patients with primary hypothyroidism taking LT4 therapy (n = 85) and patients with normal thyroid function (n = 564). Main outcomes REE and body composition assessed using indirect calorimetry and bioimpedance. Results REE was reduced in women with hypothyroidism in LT4 therapy when compared with controls (28.59 ± 3.26 vs 29.91 ± 3.59 kcal/kg fat-free mass (FFM)/day), including when adjusted for age, BMI, body composition, and level of physical activity (P = 0.008). This metabolic difference was attenuated only when adjustment for homeostatic model assessment of insulin resistance (HOMA-IR) was performed. Conclusions This study demonstrated that obese hypothyroid women in LT4 therapy, with normal serum TSH level compared with euthyroid controls, are characterized by reduced REE, in line with the hypothesis that standard LT4 replacement therapy may not fully correct metabolic alterations related to hypothyroidism. We are not able to exclude that this feature may be influenced by the modulation of insulin sensitivity at the liver site, induced by LT4 oral administration.

scholarly journals Resting energy expenditure in obese women: comparison between measured and estimated values

2016 ◽  
Vol 116 (7) ◽  
pp. 1306-1313 ◽  
Author(s):  
Vanessa Fadanelli Schoenardie Poli ◽  
Ricardo Badan Sanches ◽  
Amanda dos Santos Moraes ◽  
João Pedro Novo Fidalgo ◽  
Maythe Amaral Nascimento ◽  
...  
Keyword(s):  
Energy Expenditure ◽  
Indirect Calorimetry ◽  
Intraclass Correlation ◽  
Resting Energy Expenditure ◽  
Fat Free Mass ◽  
Interdisciplinary Therapy ◽  
Obese Women ◽  
Predictive Equations ◽  
Before And After ◽  
Resting Energy

AbstractAssessing energy requirements is a fundamental activity in clinical dietetic practice. The aim of this study was to investigate which resting energy expenditure (REE) predictive equations are the best alternatives to indirect calorimetry before and after an interdisciplinary therapy in Brazilian obese women. In all, twelve equations based on weight, height, sex, age, fat-free mass and fat mass were tested. REE was measured by indirect calorimetry. The interdisciplinary therapy consisted of nutritional, physical exercise, psychological and physiotherapy support during the course of 1 year. The average differences between measured and predicted REE, as well as the accuracy at the ±10 % level, were evaluated. Statistical analysis included paired t tests, intraclass correlation coefficients and Bland–Altman plots. Validation was based on forty obese women (BMI 30–39·9 kg/m2). Our major findings demonstrated a wide variation in the accuracy of REE predictive equations before and after weight loss in non-morbid, obese women. The equations reported by Harris–Benedict and FAO/WHO/United Nations University (UNU) were the only ones that did not show significant differences compared with indirect calorimetry and presented a bias <5 %. The Harris–Benedict equation provided 40 and 47·5 % accurate predictions before and after therapy, respectively. The FAO equation provided 35 and 47·5 % accurate predictions. However, the Bland–Altman analysis did not show good agreement between these equations and indirect calorimetry. Therefore, the Harris–Benedict and FAO/WHO/UNU equations should be used with caution for obese women. The need to critically re-assess REE data and generate regional and more homogeneous REE databases for the target population is reinforced.

scholarly journals Resting energy expenditure adaptation after short-term caloric restriction in morbidly obese women

2015 ◽  
Vol 28 (5) ◽  
pp. 505-511 ◽  
Author(s):  
Andresa Toledo TRIFFONI-MELO ◽  
Vivian Marques Miguel SUEN ◽  
Cristina Maria Mendes RESENDE ◽  
Camila Bitu Moreno BRAGA ◽  
Rosa Wanda DIEZ-GARCIA
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Energy Expenditure ◽  
Resting Energy Expenditure ◽  
Substrate Oxidation ◽  
Fat Free Mass ◽  
Morbidly Obese ◽  
Obese Women ◽  
Short Term ◽  
Resting Energy

Objective:The objective of this study was to describe changes in the resting energy expenditure, substrate oxidation rate, and body composition in morbidly obese women subjected to short-term caloric restriction. Methods:This was a prospective study that included ten obese women with body mass index greater than 40 kg/m2 and aged between 20-50 years. The participants were hospitalized for eight days and received a controlled conventional low-calorie diet, 1200 kcal/day, for seven days. Body weight, body mass index, abdominal circumference, body composition, resting energy expenditure, and substrate oxidation rate were evaluated at the beginning and at the end of the study. Results:A significant reduction in body weight (p=0.005), body mass index (p=0.005), abdominal circumference (p=0.005), fat mass (p=0.005) and fat-free mass (p=0.008) was observed at the end of the study. There was an average reduction in resting energy expenditure of approximately 124 kcal/day (5%). Substrate oxidation rate did not show statistically significant changes. There was a positive correlation only between body weight reduction and fat-free mass reduction (r=0.753; p=0.012). Conclusion:There was an adaptive response of the resting energy expenditure with short-term energy restriction in morbidly obese women with a 5% reduction in resting energy expenditure and a positive correlation between weight loss and the fat-free mass, which indicates the influence of fat-free mass on the decrease in resting energy expenditure. Therefore, short-term caloric restriction in morbidly obese women led to a decrease in resting energy expenditure and fat-free mass, which suggests a rapid adaptation of energy expenditure.

Anthropometric measured fat-free mass as essential determinant of resting energy expenditure for pregnant and non-pregnant women

Nutrition ◽  
2011 ◽  
Vol 27 (9) ◽  
pp. 885-890 ◽  
Author(s):  
Miloslav Hronek ◽  
Petr Klemera ◽  
Jindrich Tosner ◽  
Dana Hrnciarikova ◽  
Zdenek Zadak
Keyword(s):  
Energy Expenditure ◽  
Pregnant Women ◽  
Resting Energy Expenditure ◽  
Fat Free Mass ◽  
Resting Energy

Resting energy expenditure in girls with Turner syndrome

2017 ◽  
Vol 30 (3) ◽  
Author(s):  
Gerhard Binder ◽  
Laura Frank ◽  
Julian Ziegler ◽  
Gunnar Blumenstock ◽  
Roland Schweizer
Keyword(s):  
Energy Expenditure ◽  
Short Stature ◽  
Turner Syndrome ◽  
Resting Energy Expenditure ◽  
Bioelectrical Impedance ◽  
Fat Free Mass ◽  
Gh Treatment ◽  
Age Related ◽  
Resting Energy

AbstractBackground:Knowledge concerning energy metabolism in Turner syndrome (TS) is lacking. We compared the resting energy expenditure per fat-free mass (REE/FFM) in TS with other girls with short stature treated with growth hormone (GH) and age-related controls.Methods:We measured prospectively REE by spirometry under fasting conditions in the morning in 85 short prepubertal girls at the start of GH treatment. Diagnoses were TS (n=20), GH deficiency (GHD) (n=38) and small for gestational age (SGA) short stature (n=27). Additionally, 20 age-related controls were studied. Mean ages were 8.3 (TS), 7.1 (GHD), 6.9 (SGA) and 8.5 years (controls). Mean heights were −2.90 (TS), −3.32 (GHD), −3.69 (SGA) and −0.03 standard deviation scores (SDS) (controls). FFM was measured by bioelectrical impedance analysis (BIA).Results:At the start of GH girls with TS showed insignificantly higher REE per FFM (REE/FFM) (mean±SD; 65±9 kcal/kg×day) than did the other female patients (62±9 kcal/kg×day) (p>0.23). The healthy controls had significantly lower REE/FFM (35±4 kcal/kg×day) (p<0.001). Follow-up examination of the patients after 6 or 12 months revealed decreasing REE/FFM in TS (62±9 kcal/kg×day) resulting in comparable REE/FFM in all three patient groups.Conclusions:At baseline short girls with TS had insignificantly higher REE/FFM than short children with SGA or GHD, but in follow-up this difference was not detectable any more. Future studies are necessary to understand this observation.

Prediction of resting energy expenditure from fat-free mass and fat mass

1992 ◽  
Vol 56 (5) ◽  
pp. 848-856 ◽  
Author(s):  
K M Nelson ◽  
R L Weinsier ◽  
C L Long ◽  
Y Schutz
Keyword(s):  
Energy Expenditure ◽  
Fat Mass ◽  
Resting Energy Expenditure ◽  
Fat Free Mass ◽  
Resting Energy
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