CPT loaded nanoparticles based on beta-cyclodextrin-grafted poly(ethylene glycol)/poly (l-glutamic acid) diblock copolymer and their inclusion complexes with CPT

2014 ◽  
Vol 113 ◽  
pp. 230-236 ◽  
Author(s):  
Fang Du ◽  
Haijing Meng ◽  
Ke Xu ◽  
Yanyun Xu ◽  
Ping Luo ◽  
...  
1999 ◽  
Vol 31 (11_2) ◽  
pp. 1089-1094 ◽  
Author(s):  
Naotoshi Nakashima ◽  
Hiroto Murakami ◽  
Mayumi Kawamura ◽  
Daisuke Kouso ◽  
Yoshitaka Narikiyo ◽  
...  

2011 ◽  
Vol 77 (1) ◽  
pp. 75-79 ◽  
Author(s):  
Tamara Dworeck ◽  
Anne-Kathrin Petri ◽  
Noor Muhammad ◽  
Marco Fioroni ◽  
Ulrich Schwaneberg

Molecules ◽  
2020 ◽  
Vol 25 (1) ◽  
pp. 195 ◽  
Author(s):  
Abdullah M Alswieleh ◽  
Abeer M Beagan ◽  
Bayan M Alsheheri ◽  
Khalid M Alotaibi ◽  
Mansour D Alharthi ◽  
...  

This paper introduces the synthesis of well-defined 2-(tert-butylamino)ethyl methacrylate-b-poly(ethylene glycol) methyl ether methacrylate diblock copolymer, which has been grafted onto mesoporous silica nanoparticles (PTBAEMA-b-PEGMEMA-MSNs) via atom transfer radical polymerization (ATRP). The ATRP initiators were first attached to the MSN surfaces, followed by the ATRP of 2-(tert-butylamino)ethyl methacrylate (PTBAEMA). CuBr2/bipy and ascorbic acid were employed as the catalyst and reducing agent, respectively, to grow a second polymer, poly(ethylene glycol) methyl ether methacrylate (PEGMEMA). The surface structures of these fabricated nanomaterials were then analyzed using Fourier Transform Infrared (FTIR) spectroscopy. The results of Thermogravimetric Analysis (TGA) show that ATRP could provide a high surface grafting density for polymers. Dynamic Light Scattering (DLS) was conducted to investigate the pH-responsive behavior of the diblock copolymer chains on the nanoparticle surface. In addition, multifunctional pH-sensitive PTBAEMA-b-PEGMEMA-MSNs were loaded with doxycycline (Doxy) to study their capacities and long-circulation time.


2016 ◽  
Vol 27 (18) ◽  
pp. 1775-1787 ◽  
Author(s):  
Weikang Hu ◽  
Xiaoreng Feng ◽  
Xin Liu ◽  
Shulin Dai ◽  
Wen Zeng ◽  
...  

2018 ◽  
Vol 6 (8) ◽  
pp. 2189-2196 ◽  
Author(s):  
Chenguang Yang ◽  
Baiji Xue ◽  
Wantong Song ◽  
Bo Kan ◽  
Dawei Zhang ◽  
...  

Amphotericin B (AmB) is an antifungal drug used for serious fungal infections and leishmaniosis.


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