Real-time imaging tracking of a dual-fluorescent drug delivery system based on doxorubicin-loaded globin- polyethylenimine nanoparticles for visible tumor therapy

2018 ◽  
Vol 170 ◽  
pp. 163-171 ◽  
Author(s):  
Yan Zhang ◽  
Chang Wei ◽  
Feng Lv ◽  
Tianjun Liu
Keyword(s):  
Drug Delivery ◽  
Real Time ◽  
Drug Delivery System ◽  
Delivery System ◽  
Tumor Therapy ◽  
Real Time Imaging

Wavelength Dependent, Sequentially Activated, Dual Anticancer Drug Delivery System with Photoinduced Fluorescence off-on for Real Time Imaging

2017 ◽  
Vol 2 (14) ◽  
pp. 4033-4038
Author(s):  
Krishna Kalyani Behara ◽  
Y Rajesh ◽  
Amrita Chaudhuri ◽  
Sandipan Biswas ◽  
Mahitosh Mandal ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Real Time ◽  
Drug Delivery System ◽  
Anticancer Drug ◽  
Delivery System ◽  
Real Time Imaging ◽  
Anticancer Drug Delivery

scholarly journals Environment Responsive Metal–Organic Frameworks as Drug Delivery System for Tumor Therapy

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Chao Yan ◽  
Yue Jin ◽  
Chuanxiang Zhao
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Delivery Systems ◽  
Tumor Therapy ◽  
Metal Organic Frameworks ◽  
Delivery Systems ◽  
Drug Uptake ◽  
High Concentration ◽  
Metal Organic

AbstractNanoparticles as drug delivery systems can alter the drugs' hydrophilicity to affect drug uptake and efflux in tissues. They prevent drugs from non-specifically binding with bio-macromolecules and enhance drug accumulation at the lesion sites, improving therapy effects and reducing unnecessary side effects. Metal–organic frameworks (MOFs), the typical nanoparticles, a class of crystalline porous materials via self-assembled organic linkers and metal ions, exhibit excellent biodegradability, pore shape and sizes, and finely tunable chemical composition. MOFs have a rigid molecular structure, and tunable pore size can improve the encapsulation drug's stability under harsh conditions. Besides, the surface of MOFs can be modified with small-molecule ligands and biomolecule, and binding with the biomarkers which is overexpressed on the surface of cancer cells. MOFs formulations for therapeutic have been developed to effectively respond to the unique tumor microenvironment (TEM), such as high H2O2 levels, hypoxia, and high concentration glutathione (GSH). Thus, MOFs as a drug delivery system should avoid drugs leaking during blood circulation and releasing at the lesion sites via a controlling manner. In this article, we will summary environment responsive MOFs as drug delivery systems for tumor therapy under different stimuli.

scholarly journals Reactive oxygen species and enzyme dual-responsive biocompatible drug delivery system for targeted tumor therapy

2020 ◽  
Vol 324 ◽  
pp. 330-340 ◽  
Author(s):  
Ning Zhao ◽  
Bingbing Ding ◽  
Ying Zhang ◽  
Jessica L. Klockow ◽  
Ken Lau ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Tumor Therapy ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Dual Responsive

Self-Assembly Drug Delivery System Based on Programmable Dendritic Peptide Applied in Multidrug Resistance Tumor Therapy

2017 ◽  
Vol 38 (21) ◽  
pp. 1700490 ◽  
Author(s):  
Si Chen ◽  
Jin-Xuan Fan ◽  
Wen-Xiu Qiu ◽  
Li-Han Liu ◽  
Han Cheng ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Multidrug Resistance ◽  
Drug Delivery System ◽  
Delivery System ◽  
Self Assembly ◽  
Tumor Therapy

scholarly journals A sustained intravitreal drug delivery system with remote real time monitoring capability

2015 ◽  
Vol 24 ◽  
pp. 309-321 ◽  
Author(s):  
Huiyuan Hou ◽  
Alejandra Nieto ◽  
Akram Belghith ◽  
Kaihui Nan ◽  
Yangyang Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Real Time ◽  
Drug Delivery System ◽  
Delivery System ◽  
Real Time Monitoring ◽  
Intravitreal Drug Delivery

Facile exfoliation of MoS2 nanosheets by protein as a photothermal-triggered drug delivery system for synergistic tumor therapy

RSC Advances ◽  
2016 ◽  
Vol 6 (80) ◽  
pp. 77083-77092 ◽  
Author(s):  
Rui Deng ◽  
Hai Yi ◽  
Fangyi Fan ◽  
Li Fu ◽  
Yan Zeng ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Tumor Therapy ◽  
Mos2 Nanosheets ◽  
Schematic Representation ◽  
Drug Delivery Application

A schematic representation of MoS2 nanosheet synthesis and its photothermal-triggered drug delivery application.

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