Epitopes based drug design for dengue virus envelope protein: A computational approach

2017 ◽  
Vol 71 ◽  
pp. 152-160 ◽  
Author(s):  
Abdul Wadood ◽  
Aamir Mehmood ◽  
Huma Khan ◽  
Muhammad Ilyas ◽  
Ayaz Ahmad ◽  
...  
Keyword(s):  
Drug Design ◽  
Dengue Virus ◽  
Envelope Protein ◽  
Protein A ◽  
Computational Approach ◽  
Virus Envelope ◽  
Virus Envelope Protein

A Computational Approach for Identification of Epitopes in Dengue Virus Envelope Protein: A Step Towards Designing a Universal Dengue Vaccine Targeting Endemic Regions

2010 ◽  
Vol 10 (5,6) ◽  
pp. 235-246 ◽  
Author(s):  
Sajib Chakraborty ◽  
Rajib Chakravorty ◽  
Musaddeque Ahmed ◽  
Atiqur Rahman ◽  
TM Zaved Waise ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Envelope Protein ◽  
Protein A ◽  
Computational Approach ◽  
Dengue Vaccine ◽  
Virus Envelope ◽  
Virus Envelope Protein

Dengue virus envelope protein domain III-elicited antibodies mediate cross-protection against Zika virus in a mouse model

2020 ◽  
Vol 278 ◽  
pp. 197882
Author(s):  
Yongchao Zhou ◽  
Dong Chen ◽  
Lan Yang ◽  
Weiwei Zou ◽  
Zhiliang Duan ◽  
...  
Keyword(s):  
Mouse Model ◽  
Dengue Virus ◽  
Zika Virus ◽  
Envelope Protein ◽  
Cross Protection ◽  
Protein Domain ◽  
Virus Envelope ◽  
Virus Envelope Protein ◽  
Domain Iii

scholarly journals Enhanced Prokaryotic Expression of Dengue Virus Envelope Protein

2013 ◽  
Vol 16 (4) ◽  
pp. 609 ◽  
Author(s):  
Advaita Ganguly ◽  
Ravindra B. Malabadi ◽  
Dipankar Das ◽  
Mavanur R. Suresh ◽  
Hoon H Sunwoo
Keyword(s):  
Dengue Virus ◽  
Envelope Protein ◽  
Vaccine Development ◽  
Virus Envelope ◽  
E Coli ◽  
C Terminus ◽  
Virus Envelope Protein ◽  
Biological Functionality ◽  
Dengue Diagnostics

Purpose. To highlight the expression and purification of the recombinant dengue virus type-1 antigen exploiting the codon optimized full length envelope for increased yield in E. coli. Methods. A 6x His tag was inserted at the C terminus to facilitate purification. The purified protein was recognized in Western blot by Monoclonal antibody specific for the tag. The in vitro refolded recombinant protein was used to immunize mice for the development of hybridomas and also analyzed for its biological functionality with heparan sulfate binding assay. Results. The polyclonal anti-sera from the immunized mice were found to recognize the envelope protein thereby establishing the immunogenicity of the protein. Conclusion. The purified envelope protein could potentially be used towards dengue diagnostics and vaccine development efforts. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

Transient expression of dengue virus envelope protein in a plant system

2010 ◽  
Vol 150 ◽  
pp. 484-484
Author(s):  
C. Martinez ◽  
A.M Giulietti ◽  
J. Rodriguez Talou ◽  
H. Mason
Keyword(s):  
Dengue Virus ◽  
Transient Expression ◽  
Envelope Protein ◽  
Virus Envelope ◽  
Plant System ◽  
Virus Envelope Protein

scholarly journals Probing the Interaction of Dengue Virus Envelope Protein with Heparin:  Assessment of Glycosaminoglycan-Derived Inhibitors

2001 ◽  
Vol 44 (13) ◽  
pp. 2178-2187 ◽  
Author(s):  
Rory M. Marks ◽  
Hong Lu ◽  
Renuka Sundaresan ◽  
Toshihiko Toida ◽  
Atsushi Suzuki ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Envelope Protein ◽  
Virus Envelope ◽  
Virus Envelope Protein
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