Multimodality imaging of developmental splenic anomalies: tips and pitfalls

Background and Objectives: The purpose of this study was to evaluate the mammographic, sonographic and MRI findings of metaplastic breast carcinoma. Methods: In this retrospective review study, we analyzed the medical files of 9600 patients who were treated for invasive breast cancers. Clinical information, histopathologic and radiologic findings of 65 patients were included in this study. All existing radiologic images and medical reports were reviewed retrospectively. Thirty-three patients had MG, 58 patients had US and 7 patients had MRI imaging results. Results: Mammographically, the most frequent presentations of MPBC were round shape, microlobulated margin and high density masses. Calcifications with or without masses were not a frequent finding. The most common sonographic findings were round shape, partially indistinct angular margin, hypoechoic and heterogeneous echo patterns and no posterior feature masses. All lesions were presented as masses rather than non-mass enhancements on magnetic resonance imaging. Features of masses had more malignant feature on MRI than other modalities in all 7 patients. Conclusion: Metaplastic breast carcinoma is one of the rarest poorly differentiated invasive breast carcinomas. Interestingly, these aggressive tumors demonstrate benign or moderately malign features on imaging methods. This appearance of MPBC can cause it to be misdiagnosed as a benign breast lesion especially in young women. MPBC should be kept in mind in the differential diagnosis of large palpable breast masses. Therefore, follow-up at short intervals and/or multimodality imaging studies which include breast MRI are important for the diagnosis of MPBC.

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Multimodality Imaging of Neuroendocrine Tumors

Radiologic Clinics of North America ◽

10.1016/j.rcl.2020.07.008 ◽

2020 ◽

Vol 58 (6) ◽

pp. 1147-1159

Author(s):

Samuel J. Galgano ◽

Kedar Sharbidre ◽

Desiree E. Morgan

Keyword(s):

Neuroendocrine Tumors ◽

Multimodality Imaging

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Through thick and thin: Diagnosis of transthyretin cardiac amyloidosis through non-invasive multimodality imaging

Proceedings of Singapore Healthcare ◽

10.1177/20101058211006146 ◽

2021 ◽

pp. 201010582110061

Author(s):

Raja Ezman Raja Shariff ◽

Hafisyatul Aiza Zainal Abidin ◽

Sazzli Kasim

Keyword(s):

Cardiac Amyloidosis ◽

Troponin T ◽

Multimodality Imaging ◽

High Sensitivity ◽

Dark Blood ◽

Non Invasive ◽

Doppler Study ◽

Alternative Means ◽

High Sensitivity Troponin T

Cardiac amyloidosis is a severely underdiagnosed cause of heart failure with preserved ejection fraction. We report a case of highly probable transthyretin (ATTR) cardiac amyloidosis (ATTR-CA) diagnosed through the assistance of non-invasive multimodality imaging. An 81-year-old man presented with worsening dyspnoea, reduced effort tolerance and limb swelling. Examination and bedside investigations demonstrated congestive cardiac failure. On arrival, N-terminal-pro B-type natriuretic peptide was 2400 ng/L, and high-sensitivity troponin T was 78 mmol/L. Echocardiography showed severe left and right ventricular hypertrophy, and a Doppler study revealed diastolic dysfunction. Cardiac magnetic resonance imaging revealed on non-conventional dark blood sequence an abnormal inversion time for nulling myocardium suggestive of infiltrative disease, including amyloidosis. The patient was referred for nuclear-based studies involving technetium-99m pyrophosphate which demonstrated changes highly diagnostic of ATTR-CA. Early diagnosis of ATTR-CA remains paramount due to the increasing availability of disease-modifying therapies. Current guidelines recognise the role of multimodality imaging in confidently recognising the disease without the need for histological evidence in the appropriate context, providing an alternative means of diagnosis.

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Transcatheter Closure of PFO and ASD: Multimodality Imaging for Patient Selection and Perioperative Guidance

Journal of Cardiovascular Development and Disease ◽

10.3390/jcdd8070078 ◽

2021 ◽

Vol 8 (7) ◽

pp. 78

Author(s):

Gabriele Egidy Assenza ◽

Luca Spinardi ◽

Elisabetta Mariucci ◽

Anna Balducci ◽

Luca Ragni ◽

...

Keyword(s):

Patient Selection ◽

Transcatheter Closure ◽

Multimodality Imaging ◽

Deep Understanding ◽

Volume Overload ◽

Arterial Embolization ◽

Ventricular Volume ◽

Intracardiac Echocardiography ◽

Technical Details ◽

Asd Closure

Transcatheter closure of patent foramen ovale (PFO) and secundum type atrial septal defect (ASD) are common transcatheter procedures. Although they share many technical details, these procedures are targeting two different clinical indications. PFO closure is usually considered to prevent recurrent embolic stroke/systemic arterial embolization, ASD closure is indicated in patients with large left-to-right shunt, right ventricular volume overload, and normal pulmonary vascular resistance. Multimodality imaging plays a key role for patient selection, periprocedural monitoring, and follow-up surveillance. In addition to routine cardiovascular examinations, advanced neuroimaging studies, transcranial-Doppler, and interventional transesophageal echocardiography/intracardiac echocardiography are now increasingly used to deliver safely and effectively such procedures. Long-standing collaboration between interventional cardiologist, neuroradiologist, and cardiac imager is essential and it requires a standardized approach to image acquisition and interpretation. Periprocedural monitoring should be performed by experienced operators with deep understanding of technical details of transcatheter intervention. This review summarizes the specific role of different imaging modalities for PFO and ASD transcatheter closure, describing important pre-procedural and intra-procedural details and providing examples of procedural pitfall and complications.

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Multimodality Imaging for Cardiac Evaluation in Patients with COVID-19

Current Cardiology Reports ◽

10.1007/s11886-021-01483-6 ◽

2021 ◽

Vol 23 (5) ◽

Author(s):

Erin Goerlich ◽

Anum S. Minhas ◽

Monica Mukherjee ◽

Farooq H. Sheikh ◽

Nisha A. Gilotra ◽

...

Keyword(s):

Multimodality Imaging ◽

Cardiac Evaluation

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Giant tumour thrombus with congestive hepatopathy: value of multimodality imaging

Acta Cardiologica ◽

10.1080/00015385.2021.1901023 ◽

2021 ◽

pp. 1-2

Author(s):

Martijn Rogiers ◽

Jan Bogaert

Keyword(s):

Multimodality Imaging ◽

Tumour Thrombus ◽

Congestive Hepatopathy

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Multimodality imaging review of focal renal lesions

Egyptian Journal of Radiology and Nuclear Medicine ◽

10.1186/s43055-020-00391-z ◽

2021 ◽

Vol 52 (1) ◽

Author(s):

Jonathan Lyske ◽

Rishi Philip Mathew ◽

Christopher Hutchinson ◽

Vimal Patel ◽

Gavin Low

Keyword(s):

Malignant Tumors ◽

Multimodality Imaging ◽

Lymphoproliferative Disease ◽

Benign Tumors ◽

Main Body ◽

Imaging Features ◽

Focal Lesions ◽

Renal Lesions ◽

Positron Emission ◽

Neoplastic Lesions

Abstract Background Focal lesions of the kidney comprise a spectrum of entities that can be broadly classified as malignant tumors, benign tumors, and non-neoplastic lesions. Malignant tumors include renal cell carcinoma subtypes, urothelial carcinoma, lymphoma, post-transplant lymphoproliferative disease, metastases to the kidney, and rare malignant lesions. Benign tumors include angiomyolipoma (fat-rich and fat-poor) and oncocytoma. Non-neoplastic lesions include infective, inflammatory, and vascular entities. Anatomical variants can also mimic focal masses. Main body of the abstract A range of imaging modalities are available to facilitate characterization; ultrasound (US), contrast-enhanced ultrasound (CEUS), computed tomography (CT), magnetic resonance (MR) imaging, and positron emission tomography (PET), each with their own strengths and limitations. Renal lesions are being detected with increasing frequency due to escalating imaging volumes. Accurate diagnosis is central to guiding clinical management and determining prognosis. Certain lesions require intervention, whereas others may be managed conservatively or deemed clinically insignificant. Challenging cases often benefit from a multimodality imaging approach combining the morphology, enhancement and metabolic features. Short conclusion Knowledge of the relevant clinical details and key imaging features is crucial for accurate characterization and differentiation of renal lesions.

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