Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus
disease 2019 (COVID-19), continues to challenge healthcare systems worldwide, and further investigation
is required to determine its effects on the pregnant population. Prolonged viral shedding (>15-33 days),
especially without appropriate testing guidelines, can subject admitted patients to unnecessarily long
isolation, which influences emotional, physical, and clinical aspects of their antepartum course. We report
a young, primigravida Haitian female admitted to the antepartum service at 22 weeks of gestation with
preterm premature rupture of membranes (PPROM), who remained admitted in isolation for over 6 weeks
due to persistent positive SARS-CoV-2 testing. This case highlights the importance of establishing testing
guidelines to prevent unnecessary isolation, which has negative consequences for patient care. There is an
urgent need for updated guidelines for the duration of isolation based on the presence of the viable virus.