scholarly journals Prolonged SARS-CoV-2 Viral Shedding in Pregnancy and Risk of Extended inPatient Isolation: A Case Report

Author(s):  
Emad A Elsamadicy ◽  
Emad A Elsamadicy ◽  
Mary E Burgoyne ◽  
Naomi Hauser ◽  
Andrea Desai

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19), continues to challenge healthcare systems worldwide, and further investigation is required to determine its effects on the pregnant population. Prolonged viral shedding (>15-33 days), especially without appropriate testing guidelines, can subject admitted patients to unnecessarily long isolation, which influences emotional, physical, and clinical aspects of their antepartum course. We report a young, primigravida Haitian female admitted to the antepartum service at 22 weeks of gestation with preterm premature rupture of membranes (PPROM), who remained admitted in isolation for over 6 weeks due to persistent positive SARS-CoV-2 testing. This case highlights the importance of establishing testing guidelines to prevent unnecessary isolation, which has negative consequences for patient care. There is an urgent need for updated guidelines for the duration of isolation based on the presence of the viable virus.

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Mary E. Burgoyne ◽  
Emad A. Elsamadicy ◽  
Liviu Cojocaru ◽  
Andrea Desai

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for coronavirus disease 2019 (COVID-19), continues to have a devastating impact on healthcare systems worldwide, and many questions remain unanswered. The effect of COVID-19 on the pregnant population is widely debated, and the unique risks in pregnancy have not yet been elucidated. What has been established, however, is the recommendation for healthcare workers to use personal protective equipment (PPE) for both contact and airborne precautions to prevent transmission of the pathogen—adding another barrier to care for vulnerable populations. We report a case of a young woman from Haiti during her first pregnancy, who was admitted to the antepartum service at 22 weeks of gestation with preterm premature rupture of membranes (PPROM) and remained admitted in isolation, though asymptomatic, for over six weeks due to persistent positive SARS-CoV-2 testing. Our case highlights the unique barriers to care that COVID-19 poses to antepartum patients, particularly in the setting of pregnant women with persistent positive testing.


2019 ◽  
Vol 2 (2) ◽  
pp. 35-41
Author(s):  
Michelle J. Wang ◽  
Michelle Y. Lu ◽  
Elizabeth B. Ausbeck ◽  
Lorie M. Harper

Snakebites in pregnancy can result in significant maternal and fetal harm; however, the literature to guide management of this rare obstetric complication remains limited. We describe our approach to envenomation in pregnancy based on the currently available evidence. A 27-year-old G2P1 female presented at 27 weeks’ gestation after suffering a copperhead snakebite. She received antivenom and antenatal steroids without adverse maternal or fetal event. Antenatal testing was reassuring throughout admission, and she was discharged home with plans for close outpatient surveillance. She later developed preterm premature rupture of membranes and preterm labor, with delivery of a live infant at 33 weeks’ gestation. The risk of adverse maternal and fetal outcomes following snake envenomation in pregnancy may warrant closer antenatal surveillance than has been previously described.


2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Jorge A. Carvajal

Uteroplacental ischemia may cause preterm birth, either due to preterm labor, preterm premature rupture of membranes, or medical indication (in the presence of preeclampsia or fetal growth restriction). Uteroplacental ischemia is the product of defective deep placentation, a failure of invasion, and transformation of the spiral arteries by the trophoblast. The failure of normal placentation generates a series of clinical abnormalities nowadays called “deep placentation disorders”; they include preeclampsia, fetal growth restriction, preterm labor, preterm premature rupture of membranes, in utero fetal death, and placental abruption. Early reports suggested that a LC-PUFAs (long chain polyunsaturated fatty acids) rich diet reduces the incidence of deep placentation disorders. Recent randomized controlled trials are inconsistent to show the benefit of docosahexaenoic acid (DHA) supplementation during pregnancy to prevent deep placentation disorders, but most of them showed that DHA supplementation was associated with lower risk of early preterm birth. We postulate that DHA supplementation, early in pregnancy, may reduce the incidence of deep placentation disorders. If our hypothesis is correct, DHA supplementation, early in pregnancy, will become a safe and effective strategy for primary prevention of highly relevant pregnancy diseases, such as preterm birth, preeclampsia, and fetal growth restriction.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Ariel T. Levy ◽  
Melissa A. Yurkanin ◽  
Lauren A. Plante

AbstractFetal head entrapment by a uterine scar or adhesion is a rare obstetric complication. We present a case of a uterine constriction diagnosed in pregnancy that resulted in confinement of the fetal head to the lower uterine segment. The developing fetus ultimately suffered growth restriction of the head and was delivered after the mother experienced preterm premature rupture of membranes (PROM). Severe adhesions of the lower uterine segment were confirmed during the patient’s classical cesarean section.


Author(s):  
Dr. Badal Das ◽  
Dr. Krishna Pada Das ◽  
Rajiv Ranjan Das ◽  
Dr. Debobroto Roy ◽  
Dr. Arpita Sarkar ◽  
...  

Circumvallate placenta, a morphological abnormality of placenta can be defined as a thickened placenta with a raised margin in an annular shape and it is thought to be the result of a membranous fold of chorion and amnion. A 23-year-old primigravida mother was presented with grossly reduced liquor due to preterm premature rupture of membranes at 32 weeks of gestation. The preterm baby was delivered by emergency caesarean section (category-2 caesarean section). A thorough gross examination of the placenta was done and a thickened circumvallate placenta was noted with a firm white annular margin and normal umbilical cord insertion. Histopathological findings were consistent with the diagnosis of circumvallate placenta. Routine gross examination of placenta is of immense important for better understanding of pregnancy complications due to placental abnormalities like circumvallate placenta.


2007 ◽  
Vol 40 (11) ◽  
pp. 793-797 ◽  
Author(s):  
Mariangela Longini ◽  
Serafina Perrone ◽  
Piero Vezzosi ◽  
Barbara Marzocchi ◽  
Antonio Kenanidis ◽  
...  

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