Study on cryopreservation of mouse single seminiferous tubule

In the histologic and electron microscopic study of the male reproductive system of bullfrog, Rana catesbeiana, a vesicular system associated with spermiogenesis was observed. It appeared in the lumenal space of the seminiferous tubule (Fig. 1), in the heads of spermatids (Fig. 2), associated with the chromatins of the spermatid (Fig. 4). As deduced from sections, this vesicular system consisted of vesicles of various size or a large group of waving and twisted tubules (Fig. 3), After routine procedure of treatment for electron microscopy, the lumens of both of the vesicles and tubules were electron lucent.In human, vesicles and vesicular system associated with reproductive cell and tissue were reported. In abnormal spermiogenesis, flower-like body, actually vesicles, and giant vesicle associated with the head of spermatid were observed. In both cases the number of vesicle was limited from a single one to a few.

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patients with Sertoli cell-only syndrome combining with seminiferous tubule hyalinization have higher sperm retrieval rate when micro-TESE was performed

10.26226/morressier.573c1511d462b80296c980ad ◽

2016 ◽

Author(s):

Jing Zhang

Keyword(s):

Sertoli Cell ◽

Seminiferous Tubule ◽

Sperm Retrieval ◽

Retrieval Rate

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Role of Exosomes in the Exchange of Spermatozoa after Leaving the Seminiferous Tubule: A Review

Current Drug Metabolism ◽

10.2174/1389200221666200520091511 ◽

2020 ◽

Vol 21 (5) ◽

pp. 330-338

Author(s):

Luming Wu ◽

Yuan Ding ◽

Shiqiang Han ◽

Yiqing Wang

Keyword(s):

Drug Delivery ◽

Plasma Membrane ◽

Seminiferous Tubule ◽

Metabolic Diseases ◽

Inflammatory Diseases ◽

Multivesicular Bodies ◽

Extensive Search ◽

Neurological Research ◽

The One

Background: Exosomes are extracellular vesicles (EVs) released from cells upon fusion of an intermediate endocytic compartment with the plasma membrane. They refer to the intraluminal vesicles released from the fusion of multivesicular bodies with the plasma membrane. The contents and number of exosomes are related to diseases such as metabolic diseases, cancer and inflammatory diseases. Exosomes have been used in neurological research as a drug delivery tool and also as biomarkers for diseases. Recently, exosomes were observed in the seminal plasma of the one who is asthenozoospermia, which can affect sperm motility and capacitation. Objective: The main objective of this review is to deeply discuss the role of exosomes in spermatozoa after leaving the seminiferous tubule. Methods: We conducted an extensive search of the literature available on relationships between exosomes and exosomes in spermatozoa on the bibliographic database. Conclusion: : This review thoroughly discussed the role that exosomes play in the exchange of spermatozoa after leaving the seminiferous tubule and its potential as a drug delivery tool and biomarkers for diseases as well.

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