Effects of inhalation aromatherapy as a complementary therapy in pediatric patients in the clinical practice: A systematic review

2021 ◽  
pp. 101516
Author(s):  
Francisca A. Sánchez ◽  
Javiera R. Rosales ◽  
Pablo R. Godoy ◽  
R. Mauricio Barría
Keyword(s):  
Systematic Review ◽  
Clinical Practice ◽  
Pediatric Patients ◽  
Complementary Therapy

scholarly journals Clinical Practice Guideline for Systemic Antifungal Prophylaxis in Pediatric Patients With Cancer and Hematopoietic Stem-Cell Transplantation Recipients

2020 ◽  
Vol 38 (27) ◽  
pp. 3205-3216
Author(s):  
Thomas Lehrnbecher ◽  
Brian T. Fisher ◽  
Bob Phillips ◽  
Melissa Beauchemin ◽  
Fabianne Carlesse ◽  
...  
Keyword(s):  
Systematic Review ◽  
Stem Cell ◽  
Clinical Practice ◽  
Clinical Practice Guideline ◽  
Practice Guideline ◽  
Pediatric Patients ◽  
Antifungal Prophylaxis ◽  
Hematopoietic Stem ◽  
Strong Recommendation ◽  
Patients With Cancer

PURPOSE To develop a clinical practice guideline for systemic antifungal prophylaxis in pediatric patients with cancer and hematopoietic stem-cell transplantation (HSCT) recipients. METHODS Recommendations were developed by an international multidisciplinary panel that included a patient advocate. We conducted a systematic review of systemic antifungal prophylaxis in children and adults with cancer and HSCT recipients. The Grading of Recommendations Assessment, Development, and Evaluation approach was used to make strong or weak recommendations and to classify level of evidence as high, moderate, low, or very low. The panel considered directness of the data to pediatric patients. RESULTS There were 68 randomized trials included in the systematic review, of which 6 (9%) were conducted in a solely pediatric population. Strong recommendations were made to administer systemic antifungal prophylaxis to children and adolescents receiving treatment of acute myeloid leukemia, to those undergoing allogeneic HSCT pre-engraftment, and to those receiving systemic immunosuppression for graft-versus-host disease treatment. A strong recommendation was made to administer a mold-active agent with an echinocandin or a mold-active azole when systemic antifungal prophylaxis is warranted. For children younger than 13 years of age, an echinocandin, voriconazole, or itraconazole is suggested. Posaconazole may also be used in those age 13 years or older. A strong recommendation against routine administration of amphotericin as systemic antifungal prophylaxis was made. CONCLUSION We developed a clinical practice guideline for systemic antifungal prophylaxis administration in pediatric patients with cancer and HSCT recipients. Implementation and assessment of guideline-concordant rates and impacts are important future steps.

scholarly journals Mindfulness for patients with rheumatoid arthritis: systematic review

2021 ◽  
Vol 10 (2) ◽  
pp. e2610212047
Author(s):  
Ledjane Neves Oliveira ◽  
André Telis de Vilela Araújo ◽  
João Nelson Rodrigues Branco ◽  
João Carlos Marchiori de Claudio ◽  
Jeanne Liliane Marlene Michel ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Systematic Review ◽  
Clinical Practice ◽  
Web Of Science ◽  
Well Being ◽  
Complementary Therapy ◽  
Assessment Instrument ◽  
Controlled Trials ◽  
Beneficial Effects ◽  
Randomized Controlled

Objectives: To evaluate the effectiveness of mindfulness as a complementary therapy in patients with rheumatoid arthritis. Method: Protocol numbered CRD42017080108 on the PROSPERO platform. Manual searches and the Cochrane Collation assessment instrument were performed for systematic reviews in the databases CENTRAL, MEDLINE, PEDro, PsycoINFO, LILACS, Web of Science, clinical trials.gov, WHO-ICTRP and Open Gray. Randomized controlled trials were included without language restrictions or mindfulness temporality compared to placebo, psychotherapy or another equivalent strategy in patients with rheumatoid arthritis. Results: Four primary studies included (249 participants), which compared mindfulness with waiting lists, cognitive therapy and education. They presented better scores of disease activities, depressive symptoms, psychological distress, well-being, pain catastrophization, although they were classified as having a high risk of occurrence in at least one domain of the instrument used, presenting the need for robust clinical trials, proving the effectiveness of mindfulness in clinical practice. Conclusions: Beneficial effects of mindfulness in patients with rheumatoid arthritis are shown to present important results of changes in outcomes that affect the biopsychosocial dimensions in patients with. However, the evidence from the studies evaluated is of low quality, making it difficult to recommend intervention in clinical practice.

WikiRecs primary care: developing rapid recommendations for primary care through effective collaboration between systematic review and guideline teams

2018 ◽  
Vol 68 (suppl 1) ◽  
pp. bjgp18X697085
Author(s):  
Trudy Bekkering ◽  
Bert Aertgeerts ◽  
Ton Kuijpers ◽  
Mieke Vermandere ◽  
Jako Burgers ◽  
...  
Keyword(s):  
Systematic Review ◽  
Primary Care ◽  
Clinical Practice ◽  
Primary Care Physicians ◽  
Urinary Stones ◽  
Care Practice ◽  
Supporting Evidence ◽  
Supervised Exercise ◽  
Review Team ◽  
New Evidence

BackgroundThe WikiRecs evidence summaries and recommendations for clinical practice are developed using trustworthy methods. The process is triggered by studies that may potentially change practice, aiming at implementing new evidence into practice fast.AimTo share our first experiences developing WikiRecs for primary care and to reflect on the possibilities and pitfalls of this method.MethodIn March 2017, we started developing WikiRecs for primary health care to speed up the process of making potentially practice-changing evidence in clinical practice. Based on a well-structured question a systematic review team summarises the evidence using the GRADE approach. Subsequently, an international panel of primary care physicians, methodological experts and patients formulates recommendations for clinical practice. The patient representatives are involved as full guideline panel members. The final recommendations and supporting evidence are disseminated using various platforms, including MAGICapp and scientific journals.ResultsWe are developing WikiRecs on two topics: alpha-blockers for urinary stones and supervised exercise therapy for intermittent claudication. We did not face major problems but will reflect on issues we had to solve so far. We anticipate having the first WikiRecs for primary care available at the end of 2017.ConclusionThe WikiRecs process is a promising method — that is still evolving — to rapidly synthesise and bring new evidence into primary care practice, while adhering to high quality standards.

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