Decreased nerve growth factor levels in hyperthyroid Graves’ ophthalmopathy highlighting the role of neuroprotective factor in autoimmune thyroid diseases

Cytokine ◽  
2006 ◽  
Vol 35 (3-4) ◽  
pp. 109-114 ◽  
Author(s):  
I MOLNAR ◽  
A BOKK
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Nerve Growth ◽  
Autoimmune Thyroid ◽  
Graves Ophthalmopathy

scholarly journals Role of Nerve Growth Factor in Development and Persistence of Experimental Pulmonary Hypertension

2015 ◽  
Vol 192 (3) ◽  
pp. 342-355 ◽  
Author(s):  
Véronique Freund-Michel ◽  
Marcelina Cardoso Dos Santos ◽  
Christophe Guignabert ◽  
David Montani ◽  
Carole Phan ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Growth

scholarly journals The role of selenium in the pathogenesis of thyroid disease

2019 ◽  
Vol 14 (4) ◽  
pp. 192-205 ◽  
Author(s):  
Ekaterina A. Troshina ◽  
Evgeniya S. Senyushkina ◽  
Maria A. Terekhova
Keyword(s):  
Immune Response ◽  
Thyroid Disease ◽  
Animal Experiments ◽  
Optimal Level ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Increased Risk ◽  
Combined Deficiency

The past few years have been actively discussing the role of individual macro- and micronutrients as factors regulating the functional activity of organs and systems and reducing the risk of developing a number of diseases, including thyroid diseases. Selenium is one of the most important and intensively studied at present microelements. According to several studies, its low plasma level is associated with an increased risk of developing autoimmune thyroid diseases. In animal experiments, it was shown that a combined deficiency of selenium and iodine leads to more pronounced hypothyroidism than iodine deficiency alone. Some authors believe that cretinism in the newborn is a consequence of the combined deficiency of these two elements in the mother. It is also important that the optimal level of selenium is necessary both to initiate an immune response and to regulate an excessive immune response, as well as chronic inflammation. The review article discusses the relationship between selenium and thyroid pathology, discusses the role of selenium in the physiology of the thyroid gland and in the development of autoimmune diseases. The biochemical aspects of the pathogenesis of thyroid disease are presented.

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