Hypoxia, reoxygenation and cytosolic manganese superoxide dismutase (cMnSOD) silencing in Litopenaeus vannamei: Effects on cMnSOD transcripts, superoxide dismutase activity and superoxide anion production capacity

2010 ◽  
Vol 34 (11) ◽  
pp. 1230-1235 ◽  
Author(s):  
Antonio García-Triana ◽  
Tania Zenteno-Savín ◽  
Alma Beatriz Peregrino-Uriarte ◽  
Gloria Yepiz-Plascencia
Keyword(s):  
Superoxide Dismutase ◽  
Litopenaeus Vannamei ◽  
Superoxide Anion ◽  
Manganese Superoxide Dismutase ◽  
Production Capacity ◽  
Superoxide Dismutase Activity ◽  
Superoxide Anion Production ◽  
Manganese Superoxide ◽  
Anion Production ◽  
Hypoxia Reoxygenation

Polysaccharides from the green alga Caulerpa racemosa (Agardh, 1873) improve the immune response and antioxidant status in the white shrimp Litopenaeus vannamei (Boone, 1931) (Dendrobranchiata, Penaeidae)

Crustaceana ◽  
2020 ◽  
Vol 93 (6) ◽  
pp. 611-632
Author(s):  
Po-Tsang Lee ◽  
Meng-Chou Lee ◽  
Yi-Tien Ho ◽  
Zhen-Hao Liao ◽  
Huai-Ting Huang ◽  
...  
Keyword(s):  
Litopenaeus Vannamei ◽  
Superoxide Anion ◽  
Production Capacity ◽  
White Shrimp ◽  
Feed Additive ◽  
Caulerpa Racemosa ◽  
Superoxide Anion Production ◽  
Anion Production

Abstract The objective of this study was to investigate the effects of Caulerpa racemosa (Agardh, 1873) polysaccharides (CRP) on non-specific immunity of the white shrimp, Litopenaeus vannamei (Boone, 1931). The extracted polysaccharide consists of galactose, glucose, and mannose. Total polyphenolic compound and total flavonoids content in CRP were determined. In vitro CRP treatment did not alter cell viability of haemocytes and significantly activated phenoloxidase (PO) activity, superoxide anion production capacity, phagocytic rate, and index in haemocytes. Immune parameters, such as total haemocyte count, PO activity, phagocytosis, and superoxide anion production, were significantly elevated in CRP-fed shrimp during the rearing period. Malondialdehyde levels in the hepatopancreas of CRP-fed shrimp were lower than in control shrimp from day 7 to day 28. These results show that CRP exhibits antioxidant activity and can activate immune responses of white shrimp in vitro and in vivo. Therefore, CRP can be considered a functional feed additive to improve white shrimp immunity.

Reduced mitochondrial manganese-superoxide dismutase activity exacerbates glutamate toxicity in cultured mouse cortical neurons

1998 ◽  
Vol 814 (1-2) ◽  
pp. 164-170 ◽  
Author(s):  
Yibing Li ◽  
Jean-Christophe Copin ◽  
Liza F Reola ◽  
Bernard Calagui ◽  
Glenn T Gobbel ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Cortical Neurons ◽  
Manganese Superoxide Dismutase ◽  
Superoxide Dismutase Activity ◽  
Glutamate Toxicity ◽  
Manganese Superoxide

The effect of tumor necrosis factor-α on human malignant glial cells

1992 ◽  
Vol 76 (4) ◽  
pp. 652-659 ◽  
Author(s):  
Rolando F. Del Maestro ◽  
Monica Lopez-Torres ◽  
Warren B. McDonald ◽  
Eric C. Stroude ◽  
Indrasen S. Vaithilingam
Keyword(s):  
Superoxide Dismutase ◽  
Tumor Necrosis Factor ◽  
Cell Line ◽  
Tumor Necrosis ◽  
Manganese Superoxide Dismutase ◽  
Tumor Necrosis Factor Α ◽  
Superoxide Dismutase Activity ◽  
Manganese Superoxide ◽  
Factor Α ◽  
Necrosis Factor

✓ The influence of human recombinant tumor necrosis factor-α has been assessed on a cell line (U-251) derived from a human malignant glial tumor. The results of this study demonstrate that tumor necrosis factor-α at doses of 50 and 100 ng/ml: 1) did not have cytotoxic or cytostatic effects on the U-251 cell line; 2) significantly increased the intracellular activity of manganese superoxide dismutase but had no effect on copper and zinc superoxide dismutase, catalase, or glutathione peroxidase activity; and 3) did not significantly alter the intracellular or extracellular general protease and collagenase type IV activity of these cells. The resistance of the U-251 cell line to tumor necrosis factor-α cytotoxicity may be related in part to the high intrinsic manganese superoxide dismutase activity present in this cell line combined with the ability of this cell line to induce substantial amounts of protective manganese superoxide dismutase activity in response to tumor necrosis factor-α.

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