Glycogen synthase kinase-3 (GSK3) regulates TNF production and haemocyte phagocytosis in the immune response of Chinese mitten crab Eriocheir sinensis

2017 ◽  
Vol 73 ◽  
pp. 144-155 ◽  
Author(s):  
Xiaowei Li ◽  
Zhihao Jia ◽  
Weilin Wang ◽  
Lingling Wang ◽  
Zhaoqun Liu ◽  
...  
Keyword(s):  
Immune Response ◽  
Glycogen Synthase ◽  
Eriocheir Sinensis ◽  
Glycogen Synthase Kinase ◽  
Glycogen Synthase Kinase 3 ◽  
Chinese Mitten Crab ◽  
Mitten Crab

Effect of dietary L-tryptophan on the survival, immune response and gut microbiota of the Chinese mitten crab, Eriocheir sinensis

2019 ◽  
Vol 84 ◽  
pp. 1007-1017 ◽  
Author(s):  
Xiaozhen Yang ◽  
Minjie Xu ◽  
Genyong Huang ◽  
Cong Zhang ◽  
Yangyang Pang ◽  
...  
Keyword(s):  
Immune Response ◽  
Gut Microbiota ◽  
Eriocheir Sinensis ◽  
Chinese Mitten Crab ◽  
Mitten Crab

An interleukin-2 enhancer binding factor 2 homolog involved in immune response from Chinese mitten crab Eriocheir sinensis

2011 ◽  
Vol 30 (6) ◽  
pp. 1303-1309 ◽  
Author(s):  
Jialong Yang ◽  
Lingling Wang ◽  
Mengmeng Huang ◽  
Leilei Wang ◽  
Yunchao Gai ◽  
...  
Keyword(s):  
Immune Response ◽  
Interleukin 2 ◽  
Eriocheir Sinensis ◽  
Chinese Mitten Crab ◽  
Mitten Crab ◽  
Binding Factor

Immune response to abamectin-induced oxidative stress in Chinese mitten crab, Eriocheir sinensis

2020 ◽  
Vol 188 ◽  
pp. 109889 ◽  
Author(s):  
Yuhang Hong ◽  
Hongmei Yin ◽  
Yi Huang ◽  
Qiang Huang ◽  
Xiaozhen Yang
Keyword(s):  
Oxidative Stress ◽  
Immune Response ◽  
Eriocheir Sinensis ◽  
Chinese Mitten Crab ◽  
Mitten Crab

scholarly journals Role of Glycogen Synthase Kinase 3 (GSK-3) in innate immune response of human immature dendritic cells toAspergillus fumigatus

2010 ◽  
Vol 48 (4) ◽  
pp. 589-597 ◽  
Author(s):  
Katrin Spinnler ◽  
Markus Mezger ◽  
Michael Steffens ◽  
Helga Sennefelder ◽  
Oliver Kurzai ◽  
...  
Keyword(s):  
Immune Response ◽  
Dendritic Cells ◽  
Innate Immune Response ◽  
Glycogen Synthase ◽  
Innate Immune ◽  
Glycogen Synthase Kinase ◽  
Glycogen Synthase Kinase 3 ◽  
Immature Dendritic Cells

scholarly journals Glycogen Synthase Kinase-3: A Focal Point for Advancing Pathogenic Inflammation in Depression

Cells ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 2270
Author(s):  
Ryan T. McCallum ◽  
Melissa L. Perreault
Keyword(s):  
Immune Response ◽  
Glycogen Synthase ◽  
Focal Point ◽  
T Cell Differentiation ◽  
Glycogen Synthase Kinase ◽  
Glycogen Synthase Kinase 3 ◽  
Major Depressive ◽  
Wide Range ◽  
Excessive Secretion ◽  
Pro Inflammatory Cytokines

Increasing evidence indicates that the host immune response has a monumental role in the etiology of major depressive disorder (MDD), motivating the development of the inflammatory hypothesis of depression. Central to the involvement of chronic inflammation in MDD is a wide range of signaling deficits induced by the excessive secretion of pro-inflammatory cytokines and imbalanced T cell differentiation. Such signaling deficits include the glutamatergic, cholinergic, insulin, and neurotrophin systems, which work in concert to initiate and advance the neuropathology. Fundamental to the communication between such systems is the protein kinase glycogen synthase kinase-3 (GSK-3), a multifaceted protein critically linked to the etiology of MDD and an emerging target to treat pathogenic inflammation. Here, a consolidated overview of the widespread multi-system involvement of GSK-3 in contributing to the neuropathology of MDD will be discussed, with the feed-forward mechanistic links between all major neuronal signaling pathways highlighted.

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