Erratum to “Phenotypic and genotypic characterization of drug-resistant Mycobacterium tuberculosis strains” [Diagn Microbiol Infect Dis 62 (2008) 199–204]

2009 ◽  
Vol 65 (4) ◽  
pp. 462
Author(s):  
Wanessa Trindade Clemente ◽  
Stella Sala Soares Lima ◽  
Moises Palaci ◽  
Márcia S.N. Silva ◽  
Vivian F. Sumnienski Rodrigues ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Drug Resistant ◽  
Genotypic Characterization ◽  
Diagn Microbiol Infect ◽  
Phenotypic And Genotypic Characterization

Phenotypic and genotypic characterization of drug-resistant Mycobacterium tuberculosis strains

2008 ◽  
Vol 62 (2) ◽  
pp. 199-204 ◽  
Author(s):  
Wanessa Trindade Clemente ◽  
Stella Sala Soares Lima ◽  
Moises Palaci ◽  
Márcia S.N. Silva ◽  
Vivian F. Sumnienski Rodrigues ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Drug Resistant ◽  
Genotypic Characterization ◽  
Phenotypic And Genotypic Characterization

scholarly journals Genotypic characterization of multi-drug-resistant Mycobacterium tuberculosis isolates in Myanmar

2016 ◽  
Vol 22 (3) ◽  
pp. 174-179 ◽  
Author(s):  
Khin Saw Aye ◽  
Chie Nakajima ◽  
Tomoyuki Yamaguchi ◽  
Min Min Win ◽  
Mu Mu Shwe ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Drug Resistant ◽  
Genotypic Characterization

scholarly journals Genotypic characterization of drug resistant Mycobacterium tuberculosis in Quebec, 2002-2012

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Joanna Spinato ◽  
Élyse Boivin ◽  
Émilie Bélanger-Trudelle ◽  
Huguette Fauchon ◽  
Cécile Tremblay ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Drug Resistant ◽  
Genotypic Characterization

scholarly journals Phenotypic and Genotypic Characterization of Pyrazinamide Resistance among Multidrug-Resistant Mycobacterium tuberculosis Isolates in Zhejiang, China

2015 ◽  
Vol 59 (3) ◽  
pp. 1690-1695 ◽  
Author(s):  
Qiang Xia ◽  
Li-li Zhao ◽  
Feng Li ◽  
Yu-mei Fan ◽  
Yuan-yuan Chen ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Dna Sequencing ◽  
Multidrug Resistant ◽  
Drug Susceptibility Testing ◽  
Zhejiang Province ◽  
Phenotypic Data ◽  
Genotypic Characterization ◽  
Mdr Tb ◽  
Phenotypic And Genotypic Characterization

ABSTRACTTo explore the phenotypic and genotypic characterization of pyrazinamide (PZA) resistance among multidrug-resistantMycobacterium tuberculosis(MDR-TB) isolates in Zhejiang province, a total of 274 MDR-TB isolates were collected. Drug susceptibility testing and spoligotyping were performed on all clinical isolates. In addition, the mutated features of PZA-resistant loci, includingpncAandrpsA, were also analyzed by DNA sequencing. Our results showed that the prevalence of PZA resistance among MDR-TB strains in Zhejiang province was 43.07% and that PZA resistance was associated with concomitant resistance to streptomycin. The majority of PZA-resistant MDR-TB isolates belonged to the Beijing family. Mutations withinpncA, notrpsA, constituted the primary mechanism of PZA resistance. Among 118 PZA-resistant isolates, 53 different mutations were observed inpncA, and most of them were point mutations. Compared with the phenotypic data, DNA sequencing ofpncAhas sensitivity and specificity of 77.97% and 96.79%, respectively. Analysis ofpncAprovided a robust tool for rapid detection of PZA drug resistance.

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