Fecal colonization of VIM-1–producing Klebsiella pneumoniae and in vivo transfer of multidrug-resistant IncN plasmid in a renal transplant patient

2012 ◽  
Vol 72 (4) ◽  
pp. 363-366 ◽  
Author(s):  
Umaer Naseer ◽  
Bjørn Odvar Eriksen ◽  
Arnfinn Sundsfjord ◽  
Ørjan Samuelsen
2016 ◽  
Vol 60 (9) ◽  
pp. 5130-5134 ◽  
Author(s):  
Maria F. Mojica ◽  
Christopher P. Ouellette ◽  
Amy Leber ◽  
M. Brian Becknell ◽  
Monica I. Ardura ◽  
...  

ABSTRACTStenotrophomonas maltophiliais an emerging multidrug-resistant (MDR) opportunistic pathogen for which new antibiotic options are urgently needed. We report our clinical experience treating a 19-year-old renal transplant recipient who developed prolonged bacteremia due to metallo-β-lactamase-producingS. maltophiliarefractory to conventional treatment. The infection recurred despite a prolonged course of colistimethate sodium (colistin) but resolved with the use of a novel drug combination with clinical efficacy against the patient'sS. maltophiliaisolate.


2020 ◽  
Author(s):  
Junpeng Wang ◽  
Xin Li ◽  
Xiaoqiang Wu ◽  
Zhiwei Wang ◽  
Xuan Wu ◽  
...  

Abstract Background: In renal transplant recipients, carbapenem-resistant Klebsiella pneumoniae (CRKP) infection is common, and usually associated with severe clinical outcomes due to a lack of effective therapeutics.Case presentation: A 37-year-old female had a CRKP infection one month after the kidney transplantation. Since the effect of the antibiotic therapy was limited, fecal microbiota transplantation (FMT) was performed. FMT resulted in increased richness and diversity of gut microbiota and reduced relative abundance of Klebsiella. After FMT, the infection of the patient caused by CRKP was well controlled without inducing adverse effects.Conclusion: This study demonstrated the therapeutic effect of FMT on CRKP infection, and may shine some light on the treatment of the infections caused by CRKP for the patients after transplantation.


1999 ◽  
Vol 5 (1) ◽  
pp. 67-69 ◽  
Author(s):  
Balázs Nemes ◽  
Hemangshu Podder ◽  
Jenő Járay ◽  
Gabriella Dabasi ◽  
Laura Lázár ◽  
...  

2002 ◽  
Vol 34 (3) ◽  
pp. 805-806 ◽  
Author(s):  
T. Chapelle ◽  
G. Roeyen ◽  
K. De Greef ◽  
G.A. Verpooten ◽  
J.L. Bosmans ◽  
...  

2010 ◽  
Vol 25 (10) ◽  
pp. 2191-2192 ◽  
Author(s):  
Saskia H. M. Gardeniers ◽  
Djalila Mekahli ◽  
Elena Levtchenko ◽  
Evelyne Lerut ◽  
Marleen Renard ◽  
...  

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