scholarly journals Letter and response to letter: Covid-19 associated Guillain-Barré syndrome: A series of a relatively uncommon neurological complication

2021 ◽  
pp. 102370
Author(s):  
Uddalak Chakraborty ◽  
Arkapravo Hati ◽  
Atanu Chandra
Keyword(s):  
Neurological Complication ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Guillain-Barre Syndrome in a Case of Typhoid Fever: an Uncommon Association

2021 ◽  
Vol 32 (2) ◽  
pp. 142-144
Author(s):  
Abdul Basit Ibne Momen ◽  
Furial Quraishi Twinkle ◽  
Aminur Rahman ◽  
Firoz Ahmed Quraishi
Keyword(s):  
Case Report ◽  
Blood Culture ◽  
Typhoid Fever ◽  
Intravenous Immunoglobulin ◽  
Case Reports ◽  
Neurological Complication ◽  
Guillain Barre Syndrome ◽  
Intravenous Antibiotics ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Guillain-Barre syndrome (GBS) following typhoid is extremely uncommon and only few case reports are available in literature. The importance of this case report is to highlight upon the fact that a diagnosis of GBS should always be kept in mind whenever a patient of typhoid fever develops weakness. We report a young girl with blood culture proven typhoid fever that developed this very rare neurological complication quite early in the course of the disease. Following treatment with intravenous antibiotics and intravenous immunoglobulin, she was improved. Bangladesh J Medicine July 2021; 32(2) : 142-144

scholarly journals Isolated adrenocorticotropic hormone (ACTH) deficiency and Guillain-Barré syndrome occurring in a patient treated with nivolumab

2019 ◽  
Vol 12 (8) ◽  
pp. e230848 ◽  
Author(s):  
Julien Pierrard ◽  
Bénédicte Petit ◽  
Sarah Lejeune ◽  
Emmanuel Seront
Keyword(s):  
Adverse Events ◽  
Adrenocorticotropic Hormone ◽  
Checkpoint Inhibitors ◽  
Left Kidney ◽  
Neurological Complication ◽  
Guillain Barre Syndrome ◽  
Hormone Deficiency ◽  
Guillain Barré Syndrome ◽  
Guillain Barré ◽  
Lumbar Spinal

The increased use of immune checkpoint inhibitors (ICIs) has led to the observation of a variety of immune-related adverse events (irAEs). These irAEs occur usually within the first months after ICIs onset and can involve theorically all organs. We describe two rare irAEs occurring in a 70-year-old caucasian man who was treated with nivolumab for an advanced urothelial cancer of the left kidney. He developed an isolated adrenocorticotropic hormone deficiency that was diagnosed at week 19 and a neurological complication that appeared at week 79 and initially confounded with a lumbar spinal stenosis. Diagnosis of Guillain-Barré syndrome was finally confirmed with the complete resolution of symptoms after 5 days of intravenous immunoglobulin and corticosteroids. We highlight the importance of quickly recognising these potential life-threatening irAEs such as cortisol insufficiency and neurologic adverse events whose initially presentation could be non-specific.

scholarly journals Neurological Complication of Chikungunya Fever: Guillain Barre Syndrome - A Case Report

2019 ◽  
Vol 46 (3) ◽  
pp. 97-99
Author(s):  
Md Nazmul Hasan ◽  
Md Atikur Rahman ◽  
Md Abdur Rahim ◽  
Quazi Mamtaz Uddin Ahmed ◽  
Md Syedul Islam
Keyword(s):  
Case Report ◽  
Dengue Fever ◽  
Bladder Dysfunction ◽  
Neurological Complication ◽  
Guillain Barre Syndrome ◽  
Chikungunya Fever ◽  
Guillain Barré Syndrome ◽  
Major Outbreak ◽  
Sensory Involvement ◽  
Guillain Barré

Chikungunya fever has been known   as reemerging disease since 2005. Its feature is more or less like dengue fever. Major outbreak occurred in Bangladesh in 2017. Lot of complications can occur in patient suffered from it. We report a Chikungunya case presenting with Guillain-Barré syndrome (GBS) with sensory involvement and bowel- bladder dysfunction who responded to plasma pharesis. Laboratory parameters and temporality support that GBS in the complication of Chikungunya. Bangladesh Med J. 2017 Sep; 46 (3): 97-99

scholarly journals Guillain-Barré syndrome associated with arboviruses in the state of Pernambuco in 2016

2019 ◽  
Vol 32 ◽  
Author(s):  
Jacihony Aline Oliveira ◽  
Márcia Fabiana Ferreira Firmino ◽  
Dominique Babini Albquerque Cavalcanti
Keyword(s):  
Neurological Complication ◽  
Febrile Illness ◽  
The State ◽  
Guillain Barre Syndrome ◽  
Health State ◽  
Guillain Barré Syndrome ◽  
The Mean ◽  
Arbovirus Infection ◽  
Etiological Agents ◽  
Guillain Barré

Abstract Introduction: In 2016, Brazil presented an increase in the notifications related to neurological syndromes with previous register of a febrile illness compatible with arboviruses, including Guillain-Barré syndrome (GBS). Such disease is responsible for the most frequent occurrence of flaccid paralysis in the world, causing bilateral ascending muscle weakness that might affect the respiratory tract. Objective: To investigate the incidence of Guillain-Barré syndrome associated with arboviruses in Pernambuco in 2016 and to describe the confirmed/probable cases. Method: This is an observational retrospective study of GBS cases with a background of infection from dengue, chikungunya, or Zika virus notified to the Pernambuco Health State Secretariat (SES-PE). Cases notified from January 1st to December 31st, 2016 were included, which were considered as possible GBS at the time of notification. The suspect cases were investigated and classified as confirmed/probable by the positive laboratory test result, excluding the possibility of infection. Results: Forty-three suspect cases of GBS after previous arbovirus infection were notified. From these, 23 were classified as confirmed/probable for the etiological agents chikungunya and/or dengue. The mean age of the affected individuals was 37.22 ± 21.29 years and they were mostly female (56.5%). The annual incidence of GBS after arbovirus infection was 0.24 cases per 100 thousand inhabitants in the state. The neurological condition was mainly characterized by the presence of movement (91.3%) and walking (78.3%) alterations. Conclusion: The findings of this research confirm the current set of evidence and show the likelihood of GBS being a severe neurological complication of these arboviruses.

scholarly journals Zika virus detection in urine from patients with Guillain-Barré syndrome on Martinique, January 2016

2016 ◽  
Vol 21 (9) ◽  
Author(s):  
Benoît Rozé ◽  
Fatiha Najioullah ◽  
Jean-Louis Fergé ◽  
Kossivi Apetse ◽  
Yannick Brouste ◽  
...  
Keyword(s):  
Symptom Onset ◽  
Zika Virus ◽  
Neurological Complication ◽  
Virus Detection ◽  
Guillain Barre Syndrome ◽  
Zikv Infection ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

We report two cases of Guillain–Barré syndrome who had concomitant Zika virus viruria. This viruria persisted for longer than 15 days after symptom onset. The cases occurred on Martinique in January 2016, at the beginning of the Zika virus outbreak. Awareness of this possible neurological complication of ZikV infection is needed.

scholarly journals Guillain-Barre Syndrome in a patient with SARS-CoV-2 infection: Case Report

2021 ◽  
Author(s):  
Louis Fernando Marques de Almeida ◽  
Déborah Inayara Mendes Tenório de Albuquerque ◽  
Érico Induzzi Borges ◽  
Marcele Schettini ◽  
Herval Ribeiro Soares Neto ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Case Report ◽  
Muscle Strength ◽  
Neurological Complication ◽  
Laboratory Diagnosis ◽  
Lower Limbs ◽  
Guillain Barre Syndrome ◽  
Strength Grade ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Introduction: Guillain-Barré syndrome is an acute/subacute set of clinical features of immune mediated polyradiculoneuropathy, typically after respiratory or gastrointestinal viral infection. In this scenario, we described a case of the syndrome mentioned after infection by sars-cov-2 virus. Objectives and Methods: Description of a clinical case after analysis of medical history and complementary exams, in addition to literature review. Design and Setting: Case report, type of descriptive study, developed in the Institute of Medical Assistance to the State Public Servant of São Paulo. Results: A 68-year-old female patient with clinical and laboratory diagnosis of coronavirus infection, hospitalized in need of oxygen supplementation, which evolved after twelve days of symptoms with hypoesthesia on legs and feet and progressively ascending and symmetrical flaccid paraparesis that led to tetraparesis. Neurological examination showed tetraparesis (muscle strength: grade III in MMSS and grade II in MMII), hyporeflexia in MMSS and reflexes abolished in the lower limbs, plantar skin reflex in flexion in both feet, preserved facial mimicry. About complementary tests, it presented cerebrospinal fluid with albuminocytologic dissociation (cell: 1, protein: 89, glucose: 86), RT-PCR for sars-cov-2 research in cerebrospinal fluid, inconclusive, in addition to four-limb electroneuromyography performed after 19 days of onset of neurological condition, indicated polyradiculoneuropathy with involvement of sensory and motor fibers, primarily demyering. Treatment with human immunoglobulin 400 mg/kg/day for 05 days was started. The reported patient was dismissed from the hospital with significant improvement, presenting muscle strength: grade V in MMSS and grade IV in MMII and already with the ability to walk. Conclusions: the case describes a classic neurological complication associated with a virus that was once non-circulating, but currently with a big clinical relevance.

scholarly journals Guillain-Barré syndrome following COVID-19: a newly emerging post-infectious complication

2020 ◽  
Vol 13 (6) ◽  
pp. e236182 ◽  
Author(s):  
Silas Webb ◽  
Victoria CJ Wallace ◽  
David Martin-Lopez ◽  
Mahinda Yogarajah
Keyword(s):  
Respiratory Function ◽  
Neurological Complication ◽  
Sensory Neuropathy ◽  
Guillain Barre Syndrome ◽  
International Evidence ◽  
Guillain Barré Syndrome ◽  
History Of ◽  
Guillain Barré ◽  
The Uk ◽  
Post Infectious

A 57-year-old man presented with a progressive flaccid symmetrical motor and sensory neuropathy following a 1-week history of cough and malaise. He was diagnosed with Guillain-Barré syndrome secondary to COVID-19 and started on intravenous immunoglobulin. He proceeded to have worsening respiratory function and needed intubation and mechanical ventilation. This is the first reported case of this rare neurological complication of COVID-19 in the UK, but it adds to a small but growing body of international evidence to suggest a significant association between these two conditions. Increasing appreciation of this by clinicians will ensure earlier diagnosis, monitoring and treatment of patients presenting with this.

scholarly journals Guillain–Barré Syndrome as a Neurological Complication of COVID-19 Infection: A Case Series and Review of the Literature

2020 ◽  
Vol 7 (3) ◽  
pp. 156-161
Author(s):  
Hossein Mozhdehipanah ◽  
Sepideh Paybast ◽  
Reza Gorji
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Neurological Complication ◽  
Clinical Manifestations ◽  
Case Series ◽  
Final Diagnosis ◽  
Neurological Complications ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

The novel coronavirus disease 2019 (COVID-19) is a global pandemic. Although the main clinical manifestations of the COVID-19 infection have confined to the respiratory system, there is some evidence suggesting the neuro-invasive potential of the COVID-19. There are limited reports of Guillain–Barré syndrome (GBS) as a peripheral nervous system complication of COVID-19 infection. We described four patients with COVID-19 infection who developed acute polyneuropathy with a final diagnosis of Guillain–Barré syndrome. COVID-19 may have the potential to invade the peripheral nervous system. GBS, as one of the critical neurological complications of COVID-19, could be considered as a post-infectious event.

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