Guillain-Barre Syndrome in a Case of Typhoid Fever: an Uncommon Association

Guillain-Barre syndrome (GBS) following typhoid is extremely uncommon and only few case reports are available in literature. The importance of this case report is to highlight upon the fact that a diagnosis of GBS should always be kept in mind whenever a patient of typhoid fever develops weakness. We report a young girl with blood culture proven typhoid fever that developed this very rare neurological complication quite early in the course of the disease. Following treatment with intravenous antibiotics and intravenous immunoglobulin, she was improved. Bangladesh J Medicine July 2021; 32(2) : 142-144

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Neurological Complication of Chikungunya Fever: Guillain Barre Syndrome - A Case Report

Bangladesh Medical Journal ◽

10.3329/bmj.v46i3.42249 ◽

2019 ◽

Vol 46 (3) ◽

pp. 97-99

Author(s):

Md Nazmul Hasan ◽

Md Atikur Rahman ◽

Md Abdur Rahim ◽

Quazi Mamtaz Uddin Ahmed ◽

Md Syedul Islam

Keyword(s):

Case Report ◽

Dengue Fever ◽

Bladder Dysfunction ◽

Neurological Complication ◽

Guillain Barre Syndrome ◽

Chikungunya Fever ◽

Guillain Barré Syndrome ◽

Major Outbreak ◽

Sensory Involvement ◽

Guillain Barré

Chikungunya fever has been known as reemerging disease since 2005. Its feature is more or less like dengue fever. Major outbreak occurred in Bangladesh in 2017. Lot of complications can occur in patient suffered from it. We report a Chikungunya case presenting with Guillain-Barré syndrome (GBS) with sensory involvement and bowel- bladder dysfunction who responded to plasma pharesis. Laboratory parameters and temporality support that GBS in the complication of Chikungunya. Bangladesh Med J. 2017 Sep; 46 (3): 97-99

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Guillain Barré Syndrome after Thrombolysis With Streptokinase for Acute Myocardial Infarction: A Case Report

Bangladesh Journal of Neuroscience ◽

10.3329/bjn.v33i2.57525 ◽

2017 ◽

Vol 33 (2) ◽

pp. 103-104

Author(s):

Mohammad Kafil Uddin ◽

- Md Shahidullah ◽

Subash Kanti Dey ◽

Rezaul Karim Khan ◽

Md Rafiqul Islam ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Case Report ◽

Thrombolytic Therapy ◽

Intravenous Immunoglobulin ◽

Guillain Barre Syndrome ◽

Neurologic Disorder ◽

Guillain Barré Syndrome ◽

Guillain Barré

We would like to report on a patient, a 52-year-old man with acute neurologic disorder, Guillain Barré Syndrome. He was successfully treated by intravenous immunoglobulin. The patient suffered from acute extensive anterior MI. 2 weeks after thrombolytic therapy with streptokinase, he developed GBS. Bangladesh Journal of Neuroscience 2017; Vol. 33 (2): 103-104

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Guillain-Barre Syndrome in a patient with SARS-CoV-2 infection: Case Report

10.5327/1516-3180.351 ◽

2021 ◽

Author(s):

Louis Fernando Marques de Almeida ◽

Déborah Inayara Mendes Tenório de Albuquerque ◽

Érico Induzzi Borges ◽

Marcele Schettini ◽

Herval Ribeiro Soares Neto ◽

...

Keyword(s):

Cerebrospinal Fluid ◽

Case Report ◽

Muscle Strength ◽

Neurological Complication ◽

Laboratory Diagnosis ◽

Lower Limbs ◽

Guillain Barre Syndrome ◽

Strength Grade ◽

Guillain Barré Syndrome ◽

Guillain Barré

Introduction: Guillain-Barré syndrome is an acute/subacute set of clinical features of immune mediated polyradiculoneuropathy, typically after respiratory or gastrointestinal viral infection. In this scenario, we described a case of the syndrome mentioned after infection by sars-cov-2 virus. Objectives and Methods: Description of a clinical case after analysis of medical history and complementary exams, in addition to literature review. Design and Setting: Case report, type of descriptive study, developed in the Institute of Medical Assistance to the State Public Servant of São Paulo. Results: A 68-year-old female patient with clinical and laboratory diagnosis of coronavirus infection, hospitalized in need of oxygen supplementation, which evolved after twelve days of symptoms with hypoesthesia on legs and feet and progressively ascending and symmetrical flaccid paraparesis that led to tetraparesis. Neurological examination showed tetraparesis (muscle strength: grade III in MMSS and grade II in MMII), hyporeflexia in MMSS and reflexes abolished in the lower limbs, plantar skin reflex in flexion in both feet, preserved facial mimicry. About complementary tests, it presented cerebrospinal fluid with albuminocytologic dissociation (cell: 1, protein: 89, glucose: 86), RT-PCR for sars-cov-2 research in cerebrospinal fluid, inconclusive, in addition to four-limb electroneuromyography performed after 19 days of onset of neurological condition, indicated polyradiculoneuropathy with involvement of sensory and motor fibers, primarily demyering. Treatment with human immunoglobulin 400 mg/kg/day for 05 days was started. The reported patient was dismissed from the hospital with significant improvement, presenting muscle strength: grade V in MMSS and grade IV in MMII and already with the ability to walk. Conclusions: the case describes a classic neurological complication associated with a virus that was once non-circulating, but currently with a big clinical relevance.

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Guillain–Barre Syndrome following Tuberculosis: A Rare Association

Journal of Neurosciences in Rural Practice ◽

10.4103/jnrp.jnrp_387_16 ◽

2017 ◽

Vol 08 (02) ◽

pp. 296-299 ◽

Cited By ~ 1

Author(s):

Akshay Navalkishor Lakhotia ◽

Dinesh Chouksey ◽

Rahul Jain ◽

Ajoy Kumar Sodani

Keyword(s):

Case Report ◽

Pulmonary Tuberculosis ◽

Intravenous Immunoglobulin ◽

Axonal Neuropathy ◽

Guillain Barre Syndrome ◽

Early Recovery ◽

Acute Motor Axonal Neuropathy ◽

Rare Association ◽

Guillain Barré Syndrome ◽

Guillain Barré

ABSTRACTThe co-occurrence of Guillain–Barre syndrome (GBS) and tuberculosis is rare. Even in countries like India, where tuberculosis is common, there is only one case report of co-occurrence of GBS with tuberculosis. We report a case of GBS in association with sputum-positive pulmonary tuberculosis. The earliest treatment with intravenous immunoglobulin in acute motor axonal neuropathy variant of GBS would show good early recovery despite associated pulmonary tuberculosis.

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Is a second cycle of immunoglobulin justified in axonal forms of Guillain-Barré syndrome?

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x20150136 ◽

2015 ◽

Vol 73 (10) ◽

pp. 848-851 ◽

Cited By ~ 6

Author(s):

Daniel Agustin Godoy ◽

Alejandro Rabinstein

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Mechanical Ventilation ◽

Case Report ◽

Intravenous Immunoglobulin ◽

Treatment Option ◽

Guillain Barre Syndrome ◽

Ivig Infusion ◽

Guillain Barré Syndrome ◽

Guillain Barré

Objective In certain situations, severe forms of Guillain-Barré syndrome (GBS) show no response or continue to deteriorate after intravenous immunoglobulin (IVIg) infusion. It is unclear what the best treatment option would be in these circumstances.Method This is a case report on patients with severe axonal GBS in whom a second cycle of IVIg was used.Results Three patients on mechanical ventilation who presented axonal variants of GBS, with autonomic dysfunction, bulbar impairment and Erasmus score > 6, showed no improvement after IVIg infusion of 400 mg/kg/d for 5 days. After 6 weeks, we started a second cycle of IVIg using the same doses and regimen as in the previous one. On average, 5 days after the second infusion, all the patients were weaned off mechanical ventilation and showed resolution of their blood pressure and heart rate fluctuations.Conclusions A second cycle of IVIg may be an option for treating severe forms of GBS.

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Guillain-Barré Syndrome and Hyperreflexia: a case report

10.5327/1516-3180.588 ◽

2021 ◽

Author(s):

Gabriel Santaterra Barros ◽

Ana Paula Ramires Chiminazzo ◽

Maria Luiza Ricarte Ruggeri ◽

Maria Luisa Pelaes Stipp ◽

Helen Maia Tavares de Andrade

Keyword(s):

Case Report ◽

Case Reports ◽

Cranial Nerves ◽

Muscle Group ◽

Lower Limbs ◽

Guillain Barre Syndrome ◽

Clinical Criteria ◽

Distal Muscle ◽

Guillain Barré Syndrome ◽

Guillain Barré

Context: areflexia and hyporeflexia are mandatory clinical criteria for the diagnosis of Guillain-Barré Syndrome (GBS). However there are case reports in literature of GBS that exhibit hyperreflexia. Case report: Male patient, 38 years old, after weakness and pain in lower limbs, after exercise, for 4 days, without alteration of balance and sphincter. A week earlier, he had diarrhea and fever. Previous bariatric surgery. On examination: For both upper limbs, the grade of power was 5/5 in the proximal muscle group and 4/5 in the distal muscle group. For the lower limbs, the grade of power was 4/5 in both proximal and distal muscle groups. The deep tendon reflexes were brisk (+2) throughout all four limbs. Patellar tendon reflex had bigger response (+3). Babinski’s and Hoffmann’s signs were negative. Tactile, painful, vibrating sensitivity and cranial nerves examination were all intact. The presence of reflex in the four limbs with patellar hyperreflexia, made the GBS hypothesis to be disregarded. Laboratory: normal CK, TGO, aldolase, TGP, LDH and vitamin B12. Electroneuromyography (ENMG) revealed the diagnosis of AMAN. After ENMG, cerebrospinal fluid known as leukocytes: 3.1 mm³, proteins: 95.2 mg/dl. Human immunoglobulin (0.4 g/ kg/day) was prescribed for 5 days and the patient recovered in 3 months. Conclusions: The case reported by us shows the importance to take into account the GBS hypothesis in the presence of hyperreflexia, especially in axonal variants, to prevent the treatment from being mistakenly postponed.

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Severe Guillain-Barré Syndrome which Responded to Repeated Courses of Intravenous Immunoglobulin: A Case Report

Journal of King Abdulaziz University-Medical Sciences ◽

10.4197/med.10-1.11 ◽

2002 ◽

Vol 10 (1) ◽

pp. 89-92

Author(s):

DAAD AKBAR

Keyword(s):

Case Report ◽

Intravenous Immunoglobulin ◽

Immunoglobulin A ◽

Guillain Barre Syndrome ◽

Guillain Barré Syndrome ◽

Guillain Barré

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Are Repeated Cycles of Intravenous Immunoglobulin Justified in Patients With Poorly Responsive Guillain-Barré Syndrome?

The Neurohospitalist ◽

10.1177/1941874419893570 ◽

2019 ◽

Vol 10 (3) ◽

pp. 224-228

Author(s):

Hussein Algahtani ◽

Bader Shirah ◽

Khalid Alrefaei ◽

Mohammed Albassam ◽

Nawal Abdelghaffar

Keyword(s):

Case Report ◽

Intravenous Immunoglobulin ◽

Guillain Barre Syndrome ◽

Gadolinium Enhancement ◽

Multicenter Trials ◽

Guillain Barré Syndrome ◽

Reasonable Approach ◽

Life Threatening ◽

Guillain Barré ◽

The Cost

Guillain-Barré syndrome (GBS) is a life-threatening form of inflammatory polyneuropathy. Immunotherapy with intravenous immunoglobulin (IVIG) has been used successfully in the treatment of GBS. In this case report, we present a severe axonal form of GBS that showed improvement after 3 cycles of IVIG. Repeated cycles of IVIG may be an option for treating severe forms of GBS not responding to the first course of such treatment. The recent work suggests that patients who are severely affected and have severe gadolinium enhancement on the magnetic resonance imaging of the spine should be considered for retreatment with IVIG. Although the cost of management was high, the outcome was excellent, which is definitely considered a reasonable approach. This case report is an urgent call for performing large multicenter trials on the use of repeated cycles of IVIG in the management of severe cases of GBS.

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