Gestational Age-Specific Distribution of the Hammersmith Neonatal Neurological Examination Scores Among Low-Risk Neonates in Ghana

2021 ◽  
Vol 152 ◽  
pp. 105133
Author(s):  
Harriet L.S. Lawford ◽  
Mercy A. Nuamah ◽  
Helen G. Liley ◽  
Anne CC Lee ◽  
Felix Botchway ◽  
...  
1996 ◽  
Vol 54 (3) ◽  
pp. 369-374 ◽  
Author(s):  
Lygia Ohiweiler ◽  
Ligia Alfano ◽  
Newra T. Rotta

A sample of 51 children aged 7 with a history of prematurity was compared to 44 age-matched children who were born at term at the HCPA. The premature children had had gestational ages up to 37 weeks and 6 days and were born weighing less than 2500g. The control group consisted of children born with gestational age between 38 and 42 weeks and weights above 2S00g. The evaluation criteria were clinical examination, neurological examination and the evolutional neurological evaluation (ENE). The results pointed out that impulsiveness, aggressiveness, disorganization and enuresis were prevalent symptoms of developmental disturbances in the sample of prematures. Alterations at neurological examination did not discriminate between the two groups, although cerebral palsy occurred only in the proup of prematures. The ENE functions which differentiated the two groups studied were dynamic balance, appendicular and trunk-limb coordination and motor persistence.


Author(s):  
Dr. Ashok Kumar ◽  
Dr. Kanya Mukhopadhyay ◽  
Dr. Prabhjot Malhi ◽  
Dr. Anil Kumar Bhalla

According to national neonatal perinatal data (NNPD) the survival of ELBW babies has improved from 37% in 2000 to 45% in 2002-3 reports. In our neonatal unit in PGIMER the survival of ELBW babies has been 54-56% in last 5 years, however unfortunately there is very scanty reports of long term outcome of ELBW babies from India. There is very scanty report of long term growth outcome of VLBW and ELBW Babies in our country, we reported VLBW and ELBW babies in our follow up had poor catch up growth, though some catch-up was observed at 6 month but subsequent lag in growth probably reflects poor weaning at 1 year.  Infants with extremely low birth weights (ELBWs) are more susceptible to all of the possible complications of premature birth, both in the immediate neonatal period and after discharge from the nursery. These babies are at risk of poor growth and developmental. in the present study a total of 39 cases of ELBW Babies were enrolled during one year study period from July 2011- June2012 attending the neonatal follow up clinic attained 2year±3month of corrected age. Their detail birth data and postnatal illnesses retrieved from their initial hospital files and unit discharge record. A similar number of babies enrolled at 2yrs±3months of age in the control group. In the presence study, we assessed the growth, and neurological out come in extremely low birth baby attained 2yrs±3 months of corrected age. The study population consisted of 39 children of ELBW baby born during 2009 -10 at PGIMER & same number of normal birth weight children at 2yr±3 months of corrected age who satisfied the inclusion and exclusion criteria. These children were enrolled from neonatal follow up clinic who were already undergoing long term follow up. For growth outcome, we used weight, height & head circumference measurement of child, for neurological and developmental outcome used clinical neurological examination and DP-III .Base line demographic characteristics of our ELBW babies (Cases) where as follows.   Mean (S.D) gestational age of  ELBW babies was 29.87±2.3 week. Mean (S.D) birth weight 867±71.1 grams, Mean (S.D) lenght35±2.1cm & head circumference was 25.76±1.9 cm. Mean hospital stay in the ELBW babies was 48.6±19.9 days. Mean birth weight and gestational age of control group where 2684±166.2grm and 39.03±0.9 weeks. At 2year of corrected age we found  - Weight was similar in both in case group & control group. (10.04±1.4 Vs 10.75±1.1). Height and head circumference were smaller in cases than control group. (81.4±4.3 Vs 84.4±3.3 and 45.9±1.6 Vs 46.8±1.5. 5% Babies had cerebral palsy in case group (N=2/39) and none in control group. Gross development score(GDS) in Development profile-III in both study group (cases & controls) was  similar  (72.49±8.08 Vs 73.54±9.3,p=0.596). Significant difference in domains physical (84.5±7.8 Vs.90±3.5, p=0.000) and domains adaptive (81±6.7 Vs. 85.3±5.4,p= 0.003) in cases as compared to controls. There was no difference between SGA and AGA among cases in growth and neurological development. There was no difference between male and female in case group in any parameter .There is very scanty data from our country on longterm follow up of ELBW babies. Our data shows that our ELBW cohort remained small in height and had smaller head circumference though weight was similar as compared to normal control babies.  Key words: ELBW, VLBW, birth weight, neurological examination.


2020 ◽  
Author(s):  
Boniface MOIFO ◽  
Ulrich Gael TENE ◽  
Carine NJOMATCHOUA ◽  
Jean Roger MOULIOM TAPOUH ◽  
Pascal FOUMANE

Abstract Background: Mother and fetal Doppler ultrasound during pregnancy is an established and safe tool for quantitative analysis of the utero-placental and the fetoplacental blood flow and seems to be affected by Ethnic hetérogenicity. Objective. To establish normative data for the resistive index of Uterine arteries, Umbilical artery and middle cerebral artery of Cameroonian pregnant women in the second half of pregnancy using multiples of the median and percentile reference range.Methods. We conducted a cross-sectional study on 93 low risk singleton gestation women aged above 18 years between 28 and 39 weeks of gestation in two hospitals in Cameroon during 7 months. We seek for resistive index (RI) of both left and right uterine arteries (LUt and RUt), Umbilical artery (UmA) and Middle cerebral artery (MCA). We also estimated the gestational age (GA), the mother age, the fetal weight (EFW) and the cerebro – placental ration (CPR).Pearson's correlation analysis of the relationship between these RI and selected maternal parameters was done. Regression modeling across gestational age was performed to obtain the reference values and normogram curve with values ranged at 5 and 95th percentiles. P < 0.05 was considered statistically significant.Results. The mean GA and EFW was 33.5 +/- 2.92 weeks (médian of 34) and 2337.5 +/- 734 g respectively. The means RI value of target vessels were 0.55 +/- 0.077; 0.76 +/- 0.071 ; 0.48 +/- 0.077 and 0.46 +/-0.087 for UmA, McA, RUt and LUt with extremes values of des 0.38 to 0.77 ; 0.49 to 0.87; 0.30 to 0.70 and 0.29 to 0.69 respectively. Only UmA RI and CPR values had shown correlations with GA (r= - 0.338, p≤0.01 and r=0.314; p≤0.001) and EFW (r=-0.445, p≤0.001 and r=0.234; p = 0.02). No difference between LUt and RUt RI values was found. The nomogram curve for UmA, McA, RUt and LUt value revealed a general low RI values of in our sample.Conclusions. Fetal Doppler should carefully interpreted according to general low RI values during low risk singleton pregnancy shown by this study. The generated 5and 95th percentiles RI values curves for each target vessel could be useful in that way.Trial registration:N°431/UY1/FMSB/VDRC/CSD du 24 mai 2017 by the Institutional Review Board at the faculty of Medicine and Biomedical Sciences of University of Yaoundé 1.


Author(s):  
Azra Amerjee ◽  
Dur-e-Shahwar ◽  
Sana Sheikh ◽  
Iffat Ahmed ◽  
Nuruddin Mohammed ◽  
...  

Abstract Objective: Adolescent pregnancies are known to be associated with adverse outcomes. Our objective was to compare pregnancy outcomes amongst adolescents (young adolescents YA: 15-17 years; older adolescents OA: 18-19 years) and young adults (20 to 25 years) Methods: Study was conducted at Aga Khan University Hospital, Karachi. Ten-year retrospective record review was done through convenience sampling. Data was collected on predesigned proforma. Participants were 396 primiparous adolescents (15-19 years) with singleton low-risk pregnancy. Reference-group included 410 primiparous, low-risk, young adults. Pregnancies complicated with preexisting diabetes mellitus, chronic hypertension, renal disorders or cardiac diseases were excluded. Maternal /neonatal outcomes were compared amongst groups. Results: Out of 806 charts reviewed, 75 (9.3%) were YA, 321 (39.8%) were OA and 410 (50.9%) were 20-25 years old young adults. Most of the un-booked cases were in young adolescents; 17 (22.7% YA), 41 (12.8% OA) and 33 (8.0% reference -group) (p-value 0.001). This group also booked at a later gestational age; YA (19.6±10.4 weeks), OA (17.2±9.3 weeks) and controls (15.5n±8.8 weeks) (p-value 0.002). Gestational age at delivery was not significantly different among the groups. Adolescents had a decreased likelihood of cesarean section with youngest group having 29% less chance of cesarean delivery (OR 95% CI 0.41, 0.2) compared to women of 20-25 years of age.  Difference in maternal/neonatal outcomes remained insignificant between groups at univariate and multivariate analysis. .............................................................


Author(s):  
Sandeep Sethumadhavan P. ◽  
Raju Agarwal ◽  
Jayamol M. Anilkumar ◽  
Anup Ramchandran Pillai

Background: Preterm birth is the leading cause of perinatal morbidity and mortality. Transvaginal sonographic measurement of the cervix is a reliable alternative method for the assessment of cervical length as it allows better quality and more accurate visualization of the uterine cervix. Several studies have reported that cervical assessment on transvaginal sonography may be useful in the prediction of preterm delivery. The objective of this study was to assess cervical length at 20 to 24 weeks of gestation in low risk women and correlate with the gestational age at delivery.Methods: A prospective cohort study conducted in a tertiary care Military Hospital in Pune, India. 354 asymptomatic low risk antenatal women with gestational age of 20 to 24 weeks were studied. Cervical assessment with transvaginal sonography for the measurement of cervical length was performed using a 10 MHz transvaginal probe.Results: 7 percent women delivered preterm. The incidence of short cervix in low risk women was only 0.56%. 100% women with short cervix delivered preterm and, only 6.9% patients who had cervical length more than 25 mm delivered preterm. Cervical length 25 mm has got sensitivity and NPV of 100% and a specificity of 93.46%. However, the PPV was only 8%.Conclusions: The study reported significant inverse relation between short cervix and the occurrence of preterm delivery. Our findings suggest that cervical length can be used as a screening method for preterm labour in low risk women. However strong evidences from large randomized control trials would be required to assess its cost-effectiveness. 


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