scholarly journals The Prognostic Significance of Cardiac Structure and Function in Atrial Fibrillation: The ENGAGE AF–TIMI 48 Echocardiographic Substudy

2016 ◽  
Vol 29 (6) ◽  
pp. 537-544 ◽  
Author(s):  
Deepak K. Gupta ◽  
Robert P. Giugliano ◽  
Christian T. Ruff ◽  
Brian Claggett ◽  
Sabina Murphy ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Prognostic Significance ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Cardiac Structure And Function ◽  
And Function

scholarly journals Identification of Atrial Fibrillation Risk Variant RS2200733 In Indian Young Adult Population

2021 ◽  
Author(s):  
Aarthi Manoharan ◽  
Ravikumar Sambandam ◽  
Vithiavathi Sathish ◽  
Vishnu Bhat
Keyword(s):  
Atrial Fibrillation ◽  
Indian Population ◽  
Adult Population ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Risk Variant ◽  
Pitx2 Gene ◽  
Young Adult Population ◽  
Cardiac Structure And Function ◽  
And Function

Abstract Atrial fibrillation (AF) is a common cardiac arrhythmia that affects millions of people. a substantial genetic contribution to AF has been identified by number of studies over the years. The SNP that is often linked with genetic predisposition to AF is rs2200733 located in the intergenic region close to PITX2 gene which is implicated in cardiac structure and function. rs2200733 is commonly observed in major global populations. Our study aimed to establish the prevalence of this important SNP among young healthy adults in order to assess the risk of genetic susceptibility which could culminate into AF later in life. The study identified a substantial frequency of rs2200733 in Indian population at 21%.

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