Effects of zearalenone on mRNA expression and activity of cytochrome P450 1A1 and 1B1 in MCF-7 cells

2004 ◽  
Vol 58 (2) ◽  
pp. 187-193 ◽  
Author(s):  
Zengli Yu ◽  
Dongsheng Hu ◽  
Yin Li
Keyword(s):  
Cytochrome P450 ◽  
Mrna Expression ◽  
Cytochrome P450 1A1 ◽  
Expression And Activity ◽  
Mcf 7

scholarly journals Regulation of Human Cytochrome P4501A1 (hCYP1A1): A Plausible Target for Chemoprevention?

2016 ◽  
Vol 2016 ◽  
pp. 1-17 ◽  
Author(s):  
Rebeca Santes-Palacios ◽  
Diego Ornelas-Ayala ◽  
Noel Cabañas ◽  
Ana Marroquín-Pérez ◽  
Alexis Hernández-Magaña ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 1A1 ◽  
Functional Characteristics ◽  
Cytochrome P4501a1 ◽  
Important Protein ◽  
Physiological Processes ◽  
Human Cytochrome ◽  
Object Of Study ◽  
Expression And Activity ◽  
Rule Out

Human cytochrome P450 1A1 (hCYP1A1) has been an object of study due to its role in precarcinogen metabolism; for this reason it is relevant to know more in depth the mechanisms that rule out its expression and activity, which make this enzyme a target for the development of novel chemiopreventive agents. The aim of this work is to review the origin, regulation, and structural and functional characteristics of CYP1A1 letting us understand its role in the bioactivation of precarcinogen and the consequences of its modulation in other physiological processes, as well as guide us in the study of this important protein.

Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes Evidence for catalytic activity and mRNA expression

Life Sciences ◽  
2001 ◽  
Vol 69 (4) ◽  
pp. 383-393 ◽  
Author(s):  
Aparajita Dey ◽  
Devendra Parmar ◽  
Monika Dayal ◽  
Alok Dhawan ◽  
Prahlad K. Seth
Keyword(s):  
Cytochrome P450 ◽  
Catalytic Activity ◽  
Mrna Expression ◽  
Cytochrome P450 1A1 ◽  
Blood Lymphocytes
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