scholarly journals Nanosilver toxicity in gills of a neotropical fish: Metal accumulation, oxidative stress, histopathology and other physiological effects

2018 ◽  
Vol 148 ◽  
pp. 976-984 ◽  
Author(s):  
Analía Ale ◽  
Carla Bacchetta ◽  
Andrea S. Rossi ◽  
Juan Galdopórpora ◽  
Martín F. Desimone ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Metal Accumulation ◽  
Physiological Effects ◽  
Neotropical Fish

scholarly journals Heavy Metal Uptake by Herbs. V. Metal Accumulation and Physiological Effects Induced by Thiuram in Ocimum basilicum L.

2017 ◽  
Vol 228 (9) ◽  
Author(s):  
Dorota Adamczyk-Szabela ◽  
Zdzisława Romanowska-Duda ◽  
Katarzyna Lisowska ◽  
Wojciech M. Wolf
Keyword(s):  
Heavy Metal ◽  
Metal Uptake ◽  
Metal Accumulation ◽  
Ocimum Basilicum ◽  
Physiological Effects ◽  
Heavy Metal Uptake

Triple-mixture of Zn, Mn, and Fe increases bioaccumulation and causes oxidative stress in freshwater neotropical fish

2018 ◽  
Vol 37 (6) ◽  
pp. 1749-1756 ◽  
Author(s):  
Luciana Fernandes de Oliveira ◽  
Caroline Santos ◽  
Wagner Ezequiel Risso ◽  
Claudia Bueno dos Reis Martinez
Keyword(s):  
Oxidative Stress ◽  
Neotropical Fish ◽  
Triple Mixture

scholarly journals Genetic Code Expansion: A Powerful Tool for Understanding the Physiological Consequences of Oxidative Stress Protein Modifications

2018 ◽  
Vol 2018 ◽  
pp. 1-14 ◽  
Author(s):  
Joseph J. Porter ◽  
Ryan A. Mehl
Keyword(s):  
Oxidative Stress ◽  
Genetic Code ◽  
Posttranslational Modifications ◽  
Stress Protein ◽  
Physiological Effects ◽  
The Past ◽  
Arduous Task ◽  
Therapeutic Development ◽  
Genetic Code Expansion ◽  
Antibody Validation

Posttranslational modifications resulting from oxidation of proteins (Ox-PTMs) are present intracellularly under conditions of oxidative stress as well as basal conditions. In the past, these modifications were thought to be generic protein damage, but it has become increasingly clear that Ox-PTMs can have specific physiological effects. It is an arduous task to distinguish between the two cases, as multiple Ox-PTMs occur simultaneously on the same protein, convoluting analysis. Genetic code expansion (GCE) has emerged as a powerful tool to overcome this challenge as it allows for the site-specific incorporation of an Ox-PTM into translated protein. The resulting homogeneously modified protein products can then be rigorously characterized for the effects of individual Ox-PTMs. We outline the strengths and weaknesses of GCE as they relate to the field of oxidative stress and Ox-PTMs. An overview of the Ox-PTMs that have been genetically encoded and applications of GCE to the study of Ox-PTMs, including antibody validation and therapeutic development, is described.

Perinatal taurine exposure affects adult oxidative stress

2013 ◽  
Vol 305 (2) ◽  
pp. R95-R97 ◽  
Author(s):  
Wichaporn Lerdweeraphon ◽  
James Michael Wyss ◽  
Thidarut Boonmars ◽  
Sanya Roysommuti
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Early Life ◽  
Physiological Function ◽  
Perinatal Exposure ◽  
Physiological Effects ◽  
Taurine Supplementation ◽  
Adverse Health Effects ◽  
Renal Functions ◽  
Epigenetic Programming

Perinatal exposure to taurine (a β-amino acid) can alter adult physiological functions, including arterial pressure, hormonal and renal functions. Whereas perinatal taurine supplementation appears to have only minor effects on adult physiology, perinatal taurine depletion is associated with multiple adverse health effects, especially in animals postnatally exposed to other insults. New studies indicate that the mechanism for many of the physiological effects of taurine is related to the antioxidant activity of taurine. Thus the perinatal taurine depletion leads to oxidative stress in adult animals. It is likely that perinatal taurine depletion increases oxidative stress throughout life and that the early life taurine depletion leads to perinatal, epigenetic programming that impacts adult physiological function.

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