5-Bromo-oxoisoaporphine platinum(II) complexes exhibit tumor cell cytotoxcicity via inhibition of telomerase activity and disruption of c-myc G-quadruplex DNA and mitochondrial functions

2018 ◽  
Vol 145 ◽  
pp. 360-369 ◽  
Author(s):  
Zu-Zhuang Wei ◽  
Qi-Pin Qin ◽  
Ting Meng ◽  
Cai-Xing Deng ◽  
Hong Liang ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Telomerase Activity ◽  
Quadruplex Dna ◽  
Mitochondrial Functions ◽  
G Quadruplex ◽  
And Mitochondrial Functions

Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Tumor Cell Apoptosis by Organoplatinum(II) Complexes with Oxoisoaporphine

2015 ◽  
Vol 58 (5) ◽  
pp. 2159-2179 ◽  
Author(s):  
Zhen-Feng Chen ◽  
Qi-Pin Qin ◽  
Jiao-Lan Qin ◽  
Yan-Cheng Liu ◽  
Ke-Bin Huang ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Apoptosis ◽  
Telomerase Activity ◽  
Tumor Cell Apoptosis ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Dna Inhibition

Stabilization of G-quadruplex DNA and inhibition of telomerase activity studies of ruthenium(II) complexes

2014 ◽  
Vol 130 ◽  
pp. 122-129 ◽  
Author(s):  
Qian Li ◽  
Jingnan Zhang ◽  
Licong Yang ◽  
Qianqian Yu ◽  
Qingchang Chen ◽  
...  
Keyword(s):  
Telomerase Activity ◽  
Quadruplex Dna ◽  
G Quadruplex

Stabilization of G-Quadruplex DNA and Inhibition of Telomerase Activity by Square-Planar Nickel(II) Complexes

2006 ◽  
Vol 128 (18) ◽  
pp. 5992-5993 ◽  
Author(s):  
Julie E. Reed ◽  
Anna Arola Arnal ◽  
Stephen Neidle ◽  
Ramón Vilar
Keyword(s):  
Telomerase Activity ◽  
Quadruplex Dna ◽  
Square Planar ◽  
G Quadruplex

Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity and Live Cell Imaging Studies of Chiral Ruthenium(II) Complexes

2012 ◽  
Vol 18 (14) ◽  
pp. 4285-4295 ◽  
Author(s):  
Dongdong Sun ◽  
Yanan Liu ◽  
Du Liu ◽  
Rong Zhang ◽  
Xicheng Yang ◽  
...  
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Telomerase Activity ◽  
Live Cell ◽  
Imaging Studies ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Dna Inhibition

scholarly journals Microwave-Assisted Synthesis of Arene Ru(II) Complexes Induce Tumor Cell Apoptosis Through Selectively Binding and Stabilizing bcl-2 G-Quadruplex DNA

Materials ◽  
2016 ◽  
Vol 9 (5) ◽  
pp. 386 ◽  
Author(s):  
Yanhua Chen ◽  
Qiong Wu ◽  
Xicheng Wang ◽  
Qiang Xie ◽  
Yunyun Tang ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Apoptosis ◽  
Microwave Assisted Synthesis ◽  
Tumor Cell Apoptosis ◽  
Quadruplex Dna ◽  
Microwave Assisted ◽  
G Quadruplex

scholarly journals Targeting Human Telomeric G-Quadruplex DNA and Inhibition of Telomerase Activity With [(dmb)2Ru(obip)Ru(dmb)2]4+

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e84419 ◽  
Author(s):  
Shuo Shi ◽  
Shane Gao ◽  
Tongcheng Cao ◽  
Jie Liu ◽  
Xing Gao ◽  
...  
Keyword(s):  
Telomerase Activity ◽  
Quadruplex Dna ◽  
G Quadruplex

scholarly journals Phenyl 1,2,3-Triazole-Thymidine Ligands Stabilize G-Quadruplex DNA, Inhibit DNA Synthesis and Potentially Reduce Tumor Cell Proliferation over 3′-Azido Deoxythymidine

PLoS ONE ◽  
2013 ◽  
Vol 8 (8) ◽  
pp. e70798 ◽  
Author(s):  
Jerald Mahesh Kumar ◽  
Mohammed M. Idris ◽  
Gunda Srinivas ◽  
Pallerla Vinay Kumar ◽  
Vuppalapaty Meghah ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Tumor Cell ◽  
Dna Synthesis ◽  
Tumor Cell Proliferation ◽  
Quadruplex Dna ◽  
G Quadruplex
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