Design, synthesis and anti-inflammatory activity of 3-amino acid derivatives of ocotillol-type sapogenins

2020 ◽  
Vol 202 ◽  
pp. 112507 ◽  
Author(s):  
Gangqiang Yang ◽  
Meng Gao ◽  
Yixiao Sun ◽  
Conghui Wang ◽  
Xiaojuan Fang ◽  
...  
Keyword(s):  
Amino Acid ◽  
Inflammatory Activity ◽  
Amino Acid Derivatives ◽  
Design Synthesis ◽  
Anti Inflammatory ◽  
Derivatives Of

Three Amino Acid Derivatives of Valproic Acid: Design, Synthesis, Theoretical and Experimental Evaluation as Anticancer Agents

2014 ◽  
Vol 14 (7) ◽  
pp. 984-993 ◽  
Author(s):  
Gabriela Luna-Palencia ◽  
Federico Martinez-Ramos ◽  
Ismael Vasquez-Moctezuma ◽  
Manuel Fragoso-Vazquez ◽  
Jessica Mendieta-Wejebe ◽  
...  
Keyword(s):  
Valproic Acid ◽  
Amino Acid ◽  
Anticancer Agents ◽  
Experimental Evaluation ◽  
Amino Acid Derivatives ◽  
Design Synthesis ◽  
Derivatives Of

Design, Synthesis, and Local Anti-Inflammatory Activity of 17β-Carboxamide Derivatives of Glucocorticoids

2014 ◽  
Vol 347 (11) ◽  
pp. 786-797 ◽  
Author(s):  
Vladimir Dobričić ◽  
Bojan Marković ◽  
Nikola Milenković ◽  
Vladimir Savić ◽  
Vesna Jaćević ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Design Synthesis ◽  
Anti Inflammatory ◽  
Derivatives Of

Design, Synthesis and QSAR Studies on a Series of 2, 5-Disubstituted- 1,3,4-oxadiazole Derivatives of Diclofenac and Naproxen for Analgesic and Anti-inflammatory Activity

2015 ◽  
Vol 11 (8) ◽  
pp. 753-763 ◽  
Author(s):  
Kaliappan Ilango ◽  
Parthiban Valentina ◽  
Gajendra Kumar ◽  
Dushyant Dixit ◽  
Shrikant Nilewar ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Design Synthesis ◽  
Qsar Studies ◽  
Oxadiazole Derivatives ◽  
Anti Inflammatory ◽  
Derivatives Of

Synthesis and anti-inflammatory activity of some amides of salicylic acid ? ?-amino acid derivatives

1978 ◽  
Vol 12 (9) ◽  
pp. 1150-1153 ◽  
Author(s):  
N. M. Divanyan ◽  
S. A. Kazaryan ◽  
L. Kh. Galstyan ◽  
O. L. Mndzhoyan ◽  
V. G. Sarkisyan ◽  
...  
Keyword(s):  
Salicylic Acid ◽  
Amino Acid ◽  
Inflammatory Activity ◽  
Amino Acid Derivatives ◽  
Anti Inflammatory

Synthesis, anti-inflammatory activity and molecular docking studies of 2,5-diarylfuran amino acid derivatives

2012 ◽  
Vol 47 ◽  
pp. 52-58 ◽  
Author(s):  
Hélio A. Stefani ◽  
Giancarlo V. Botteselle ◽  
Julio Zukerman-Schpector ◽  
Ignez Caracelli ◽  
Denis da Silva Corrêa ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Amino Acid ◽  
Docking Studies ◽  
Inflammatory Activity ◽  
Amino Acid Derivatives ◽  
Molecular Docking Studies ◽  
Anti Inflammatory

New ursolic acid derivatives bearing 1,2,3-triazole moieties: design, synthesis and anti-inflammatory activity in vitro and in vivo

2021 ◽  
Author(s):  
Tian-Yi Zhang ◽  
Chun-Shi Li ◽  
Li-Ting Cao ◽  
Xue-Qian Bai ◽  
Dong-Hai Zhao ◽  
...  
Keyword(s):  
Ursolic Acid ◽  
Inflammatory Activity ◽  
Design Synthesis ◽  
Anti Inflammatory

scholarly journals Novel Amino Acid Derivatives of Quinolines as Potential Antibacterial and Fluorophore Agents

2020 ◽  
Vol 88 (4) ◽  
pp. 57
Author(s):  
Oussama Moussaoui ◽  
Rajendra Bhadane ◽  
Riham Sghyar ◽  
El Mestafa El Hadrami ◽  
Soukaina El Amrani ◽  
...  
Keyword(s):  
Amino Acid ◽  
Methyl Esters ◽  
Amino Acid Derivatives ◽  
Bacterial Strains ◽  
Fluorescent Properties ◽  
Topoisomerase Iv ◽  
Microdilution Method ◽  
Hydrolysis Of ◽  
Derivatives Of

A new series of amino acid derivatives of quinolines was synthesized through the hydrolysis of amino acid methyl esters of quinoline carboxamides with alkali hydroxide. The compounds were purified on silica gel by column chromatography and further characterized by TLC, NMR and ESI-TOF mass spectrometry. All compounds were screened for in vitro antimicrobial activity against different bacterial strains using the microdilution method. Most of the synthesized amino acid-quinolines show more potent or equipotent inhibitory action against the tested bacteria than their correspond esters. In addition, many of them exhibit fluorescent properties and could possibly be utilized as fluorophores. Molecular docking and simulation studies of the compounds at putative bacterial target enzymes suggest that the antimicrobial potency of these synthesized analogues could be due to enzyme inhibition via their favorable binding at the fluoroquinolone binding site at the GyrA subunit of DNA gyrase and/or the ParC subunit of topoisomerase-IV.

Synthesis of Some Amino Acid Derivatives of Styrene1

1959 ◽  
Vol 81 (2) ◽  
pp. 377-382 ◽  
Author(s):  
L. R. Morris ◽  
R. A. Mock ◽  
C. A. Marshall ◽  
J. H. Howe
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Derivatives Of
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