Pre-treatment DQA using ArcCheck for craniospinal irradiation with helical tomotherapy

2016 ◽  
Vol 32 ◽  
pp. 32
Author(s):  
G. Iacoviello ◽  
B.F. Abbate ◽  
V. Caputo ◽  
F. D'Alia ◽  
K.K. Gallias ◽  
...  
Keyword(s):  
Helical Tomotherapy ◽  
Craniospinal Irradiation ◽  
Pre Treatment

scholarly journals Practical Aspects of the Application of Helical Tomotherapy for Craniospinal Irradiation

2020 ◽  
Author(s):  
Joongyo Lee ◽  
Euidam Kim ◽  
Nalee Kim ◽  
Hwa Kyung Byun ◽  
Chang-Ok Suh ◽  
...  
Keyword(s):  
Weight Loss ◽  
Risk Factor ◽  
Pediatric Patients ◽  
Helical Tomotherapy ◽  
Craniospinal Irradiation ◽  
Setup Errors ◽  
Ap Weight ◽  
Setup Verification ◽  
The Difference ◽  
Pre Treatment

Abstract We investigated the practical aspects of the application of craniospinal irradiation using helical tomotherapy (HT-CSI) by evaluating interfractional setup errors and intrafractional movement during each treatment in 83 patients undergoing HT-CSI between January 2014 and December 2018. Interfractional setup errors in each axis (mediolateral; ML, craniocaudal; CC, and anteroposterior; AP) were assessed as differences between pre-treatment megavoltage computed tomography (MVCT) images scanned (zygomatic arch to the C4 spine) and planning CT images. Intrafractional movements were evaluated as the difference between pre-treatment and post-treatment MVCT (T12–L4 spine) images at each fraction. Median interfractional setup error was acceptable in every axis (ML: 1.6 mm, CC: 1.9 mm, AP: 3.1 mm). Seven patients (8.4%) experienced significant intrafractional displacement from 1 to 10 fractions (0.35% for ML, 0.77% for CC, 1.26% for AP). Weight loss grade 1+ during treatment (p=0.016) was an independent risk factor for significant intrafractional displacement. The risk factor for significant intrafractional movement in pediatric patients was weight loss grade 1+ (p=0.020), while there was no factor in adults. HT-CSI could be a feasible treatment modality with acceptable setup verification. Inter- and intrafractional errors were acceptable; paying attention to weight loss during treatment is necessary, especially in pediatric patients.

scholarly journals Practical aspects of the application of helical tomotherapy for craniospinal irradiation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Joongyo Lee ◽  
Euidam Kim ◽  
Nalee Kim ◽  
Hwa Kyung Byun ◽  
Chang-Ok Suh ◽  
...  
Keyword(s):  
Weight Loss ◽  
Risk Factor ◽  
Pediatric Patients ◽  
Helical Tomotherapy ◽  
Craniospinal Irradiation ◽  
Setup Errors ◽  
Ap Weight ◽  
Setup Verification ◽  
The Difference ◽  
Pre Treatment

AbstractWe investigated the practical aspects of the application of craniospinal irradiation using helical tomotherapy (HT-CSI) by evaluating interfractional setup errors and intrafractional movement during each treatment in 83 patients undergoing HT-CSI between January 2014 and December 2018. Interfractional setup errors in each axis (mediolateral; ML, craniocaudal; CC, and anteroposterior; AP) were assessed as differences between pre-treatment megavoltage computed tomography (MVCT) images scanned (zygomatic arch to the C4 spine) and planning CT images. Intrafractional movements were evaluated as the difference between pre-treatment and post-treatment MVCT (T12–L4 spine) images at each fraction. Median interfractional setup error was acceptable in every axis (ML: 1.6 mm, CC: 1.9 mm, AP: 3.1 mm). Seven patients (8.4%) experienced significant intrafractional displacement from 1 to 10 fractions (0.34% for ML, 0.74% for CC, 1.21% for AP). Weight loss grade 1+ during treatment (p = 0.016) was an independent risk factor for significant intrafractional displacement. The risk factor for significant intrafractional movement in pediatric patients was weight loss grade 1+ (p = 0.020), while there was no factor in adults. HT-CSI could be a feasible treatment modality with acceptable setup verification. Inter- and intrafractional errors were acceptable; paying attention to weight loss during treatment is necessary, especially in pediatric patients.

scholarly journals Toxicity Reduction after Craniospinal Irradiation via Helical Tomotherapy in Patients with Medulloblastoma: A Unicentric Retrospective Analysis

Cancers ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 501
Author(s):  
Anil Öztunali ◽  
Khaled Elsayad ◽  
Sergiu Scobioala ◽  
Mohammed Channaoui ◽  
Uwe Haverkamp ◽  
...  
Keyword(s):  
Helical Tomotherapy ◽  
Radiation Therapy Oncology Group ◽  
Survival Rates ◽  
Local Control Rate ◽  
Craniospinal Irradiation ◽  
Lower Grade ◽  
European Organization ◽  
Efficacious Treatment ◽  
Eortc Criteria ◽  
Reduced Rate

Objectives: Recent trials with craniospinal irradiation (CSI) via helical Tomotherapy (HT) demonstrated encouraging medulloblastoma results. In this study, we assess the toxicity profile of different radiation techniques and estimate survival rates. Materials and Methods: We reviewed the records of 46 patients who underwent irradiation for medulloblastoma between 1999 and 2019 (27 conventional radiotherapy technique (CRT) and 19 HT). Patient, tumor, and treatment characteristics, as well as treatment outcomes—local control rate (LCR), event-free survival (EFS), and overall survival (OS)—were reviewed. Acute and late adverse events (AEs) were evaluated according to the Radiation Therapy Oncology Group and the European Organization for Research and Treatment of Cancer (RTOG/EORTC) criteria. Results: In total, 43 courses of CSI and three local RT were administered to the 46 patients: 30 were male, the median age was 7 years (range 1–56). A median total RT dose of 55 Gy (range 44–68) and a median CSI dose of 35 Gy (range, 23.4–40) was delivered. During follow-up (median, 99 months), six patients (13%) developed recurrence. The EFS rate after 5 years was 84%. The overall OS rates after 5 and 10 years were 95% and 88%, respectively. There were no treatment-related deaths. Following HT, a trend towards lower grade 2/3 acute upper gastrointestinal (p = 0.07) and subacute CNS (p = 0.05) toxicity rates was detected compared to CRT-group. The risk of late CNS toxicities, mainly grade 2/3, was significantly lower following HT technique (p = 0.003). Conclusion: CSI via HT is an efficacious treatment modality in medulloblastoma patients. In all, we detected a reduced rate of several acute, subacute, and chronic toxicities following HT compared to CRT.

Daily setup uncertainty analysis for craniospinal irradiation using helical tomotherapy

2013 ◽  
Vol 3 (4) ◽  
pp. 349-355 ◽  
Author(s):  
Rolina Al-Wassia ◽  
Houda Bahig ◽  
Emily Poon ◽  
William Parker ◽  
Carolyn Freeman
Keyword(s):  
Uncertainty Analysis ◽  
Helical Tomotherapy ◽  
Craniospinal Irradiation

PO-0655 REDUCING HAEMATOLOGICAL TOXICITY FOR ADULT PATIENTS RECEIVING CRANIOSPINAL IRRADIATION WITH HELICAL TOMOTHERAPY

2012 ◽  
Vol 103 ◽  
pp. S256
Author(s):  
K. Petersson ◽  
M. Gebre-Medhin ◽  
C. Ceberg ◽  
P. Engström ◽  
T. Knöös ◽  
...  
Keyword(s):  
Helical Tomotherapy ◽  
Haematological Toxicity ◽  
Adult Patients ◽  
Craniospinal Irradiation

scholarly journals Analysis of Clinical Patient-Specific Pre-Treatment Quality Assurance with the New Helical TomoTherapy® Platform, following the AAPM TG-218 Report

2021 ◽  
Author(s):  
Marco Fusella ◽  
Samuele Cavinato ◽  
Alessandra Germani ◽  
Marta Paiusco ◽  
Nicola Pivato ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Helical Tomotherapy ◽  
Treatment Quality ◽  
Patient Specific ◽  
Mean Values ◽  
Clinical Patient ◽  
Passing Rate ◽  
Pre Treatment ◽  
Delivery Accuracy ◽  
Global And Local

Abstract Purpose: This study presents patient-specific quality assurance (QA) results from the first 395 clinical cases for the new helical TomoTherapy® platform (Radixact) coupled with dedicated Precision TPS.Methods: The passing rate of the Gamma Index (GP%) of 395 helical QA of patient-specific Tomotherapy, acquired with ArcCHECK, is presented, analysed and correlated to various parameters of the plan. Following TG-218 recommendations, the clinic specific action limit (ALcs) and tolerance limit (TLcs) were calculated for our clinic and monitored during the analysed period.Results: the mean values ​​(± 1 standard deviation) of GP% (3% / 2mm) (both global and local normalization) are: 97.6% and 90.9%, respectively. The proposed ALcs and TLcs, after a period of two years’ process monitoring are 89.4% and 91.1% respectively.Conclusions: The phantom measurements closely match the planned dose distributions, demonstrating that the calculation accuracy of the new Precision TPS and the delivery accuracy of the Radixact unit are adequate, with respect to international guidelines and reports. Furthermore, a first correlation with the planning parameters was made. Action and tolerance limits have been set for the new Radixact Linac.

Sign in / Sign up

Export Citation Format

Share Document