Protective effects of the free radical scavenger edaravone on acute pancreatitis-associated lung injury

2010 ◽  
Vol 630 (1-3) ◽  
pp. 152-157 ◽  
Author(s):  
Tao Yang ◽  
Yan-Fei Mao ◽  
Shuang-Qing Liu ◽  
Jiong Hou ◽  
Zhi-Yang Cai ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Free Radical ◽  
Lung Injury ◽  
Free Radical Scavenger ◽  
Radical Scavenger ◽  
Protective Effects

A Free Radical Scavenger (Lazaroid U75412E) Attenuates Tumor Necrosis Factor-Alpha Generation in a Rabbit Model of Smoke-Induced Lung Injury

Respiration ◽  
1997 ◽  
Vol 64 (5) ◽  
pp. 358-363 ◽  
Author(s):  
Shengjun Wang ◽  
Clark Lantz ◽  
Evelyn D. Rider ◽  
Guan Jie Chen ◽  
Veronica Breceda ◽  
...  
Keyword(s):  
Free Radical ◽  
Tumor Necrosis Factor ◽  
Lung Injury ◽  
Tumor Necrosis ◽  
Rabbit Model ◽  
Free Radical Scavenger ◽  
Radical Scavenger ◽  
Necrosis Factor Alpha ◽  
Factor Alpha ◽  
Necrosis Factor

scholarly journals Effects of edaravone, a free-radical scavenger, on bleomycin-induced lung injury in mice

2008 ◽  
Vol 32 (5) ◽  
pp. 1337-1343 ◽  
Author(s):  
S. Tajima ◽  
M. Bando ◽  
Y. Ishii ◽  
T. Hosono ◽  
H. Yamasawa ◽  
...  
Keyword(s):  
Free Radical ◽  
Lung Injury ◽  
Free Radical Scavenger ◽  
Radical Scavenger

scholarly journals Antimutagenic and antirecombinagenic activities of noni fruit juice in somatic cells of Drosophila melanogaster

2013 ◽  
Vol 85 (2) ◽  
pp. 585-594 ◽  
Author(s):  
LEONARDO P. FRANCHI ◽  
NILZA N. GUIMARAES ◽  
LAISE R. DE ANDRADE ◽  
HELOISA H.R. DE ANDRADE ◽  
MAURICIO LEHMANN ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Free Radical ◽  
Fruit Juice ◽  
Marked Decrease ◽  
Free Radical Scavenger ◽  
Morinda Citrifolia ◽  
Radical Scavenger ◽  
Protective Effects ◽  
Genotoxic Effects ◽  
Induced Mutant

Noni, a Hawaiian name for the fruit of Morinda citrifolia L., is a traditional medicinal plant from Polynesia widely used for the treatment of many diseases including arthritis, diabetes, asthma, hypertension and cancer. Here, a commercial noni juice (TNJ) was evaluated for its protective activities against the lesions induced by mitomycin C (MMC) and doxorrubicin (DXR) using the Somatic Mutation and Recombination Test (SMART) in Drosophila melanogaster. Three-day-old larvae, trans-heterozygous for two genetic markers (mwh and flr3 ), were co-treated with TNJ plus MMC or DXR. We have observed a reduction in genotoxic effects of MMC and DXR caused by the juice. TNJ provoked a marked decrease in all kinds of MMC- and DXR-induced mutant spots, mainly due to its antirecombinagenic activity. The TNJ protective effects were concentration-dependent, indicating a dose-response correlation, that can be attributed to a powerful antioxidant and/or free radical scavenger ability of TNJ.

Preventive effects of edaravone, a free radical scavenger, on lipopolysaccharide-induced lung injury in mice

Respirology ◽  
2008 ◽  
Vol 13 (5) ◽  
pp. 646-653 ◽  
Author(s):  
Shunji TAJIMA ◽  
Manabu SODA ◽  
Masashi BANDO ◽  
Munehiro ENOMOTO ◽  
Hideaki YAMASAWA ◽  
...  
Keyword(s):  
Free Radical ◽  
Lung Injury ◽  
Free Radical Scavenger ◽  
Radical Scavenger ◽  
Preventive Effects
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