morinda citrifolia
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2022 ◽  
Vol 27 (2) ◽  
pp. 73-77
Author(s):  
Dayu Nirwana Putri ◽  
Sri Widyarti ◽  
Yoga Dwi Jatmiko

Free radicals are constantly produced by either cell metabolism or from external sources. At high concentration, they induced a tissue damage called oxidative stress. Soursop leaf (Annona muricata L.) and noni leaf (Morinda citrifolia L.) are medicinal plants with potency as antioxidants. This study aimed to evaluate the capacity of Lactobacillus plantarum BP102 in elevating the antioxidant activity of soursop and noni leaves. Dried-powder and methanol extract of soursop and noni leaves were diluted with sterile distilled water 3 g/30 mL and 0.3 g/30 mL, respectively, inoculated with 1% (v/v) of L. plantarum BP102 inoculum. The antioxidant activity was carried out using the 2.2-diphenyl-1-picrylhydrazyl (DPPH) method. The antioxidant activity increased in dried-powder and methanol extract of soursop and noni leaves with different activity levels after being fermented using L. plantarum BP102 based on IC50. The increasing antioxidant activity in dried-powder of soursop leaves IC50 6.41±0.06 to 0.034±0.01 mg/mL (99.5%) was higher than of the methanol extract IC50 2.78±0.00 to 0.11±0.01 mg/mL (96%). Unfortunately, the effect of fermentation towards noni leaves could only be observed in the form of methanol extract IC50 12.8±0.01 to 0.33±0.02 mg/mL (increased by 97.4%), the dried-powder of noni leaves was suspended and produced a dark color. The probiotic L. plantarum BP102 was used as a fermented agent in increasing the bioactive compounds especially related to antioxidant activity.


2021 ◽  
Vol 3 (2) ◽  
pp. 102-109
Author(s):  
Hanna Fatarani Has ◽  
Nur Azizah ◽  
Juliani Juliani
Keyword(s):  

Mengkudu ( Morinda citrifolia L) merupakan salah satu tanaman obat yang berkhasiat untuk menurunkan tekanan darah. Mengkudu memiliki kandungan bahan aktif scopoletin yang dapat menurunkan resistensi perifer. Pengolahan mengkudu biasanya dalam bentuk tablet, kapsul, dan seduhan, dengan demikian perlu adanya bentuk yang lebih praktis yaitu dalam bentuk serbuk effervescent. Penelitian ini bertujuan untuk membuat serbuk effervescent dari ekstrak buah mengkudu. Metode penelitian ini adalah eksperimental laboratorium, dengan membuat berbagai jenis formulasi serbuk effervescent dari ekstrak buah mengkudu dengan variasi kandungan asam basa yaitu formula A (2,5:1,5:1), formula B (2:1,5:1,5), formula C (3:1:1). Evaluasi sediaan yang dilakukan yaitu uji pH, waktu alir, sudut diam, waktu dispersi, dan uji organoleptik. Hasil penelitian menunjukan bahwa formula II yang paling mendekati syarat serbuk effervescent yang baik dengan hasil uji organoleptik bau dan rasanya lemah, waktu larutnya 1,59 detik, dan pH nya 4. Kesimpulannya ekstrak buah mengkudu ini dapat dijadikan serbuk effervescent dengan rancangan formula tersebut, namun belum memenuhi standar karena tidak terdapat satu formulapun yang memenuhi semua standar uji evaluasi. Adapun variasi asam basa memiliki pengaruh pada formula yang dibuat sehi ngga pada hasil uji evaluasi beberapa diantaranya tidak memenuhi standar uji evaluasi yang telah ditentukan.


2021 ◽  
Vol 13 (2) ◽  
pp. 137-146
Author(s):  
Rizki Awaluddin ◽  
Binti Sholihatin ◽  
Nurul Marfu'ah ◽  
Solikah Ana Estikomah

Abstract. Aedes sp. is a vector of the dengue virus that causes Dengue Hemorrhagic Fever (DHF).Larvicides are the optimal method for controlling mosquito development. Temephos is a larvicidalagent of the organophosphate group which is reported to cause side eff ects and ecological hazards,as well as resistance based on reports in several country. This study aims to determine the larvicidalactivity of the n-hexane fraction of Morinda citrifolia leaf ethanol extract on Aedes sp. The compoundgroups in the fraction were identifi ed using TLC through UV light and spray reagents. There were sixtypes of treatment including four concentration fractions (400, 600, 800, and 1000 ppm) as treatment,positive control (temephos 1%) and negative control 1% acetone solution. Twenty-fi ve mosquito larvaeof Aedes sp. tested for each treatment. Larval mortality was recorded and LC50 and LC99 values wereanalyzed using the probit. The results showed that the TLC test of the n-hexane fraction was positivefor terpenoids, anthraquinones, phenols, tannins, and fl avonoids. The results showed that the LC50 andLC99 values were 1040 ppm and 2439 ppm. Therefore, the n-hexane fraction of the ethanol extract hadlarvicidal activity on Aedes sp with li le toxicity.


2021 ◽  
Vol 5 (4) ◽  
pp. 365-368
Author(s):  
Muthmainah Tuldjanah ◽  
Niluh Puspita Dewi ◽  
Dian Rahmawati

Morinda citrifolia. L leaf is a plant that has the potential as an antioxidant due to the presence of compounds in the form of flavonoids and other phenolic compounds that can function as natural antioxidants. In connection with this, research was carried out to Morinda citrifolia. L formulate leaf extract in the form of effervescent granules. Morinda citrifolia leaf extract was macerated with ethanol 96% as solvent. Phytochemical screening showsthat the extract contains flavonoids, tannins, saponins and alkaloids. The extract was formulated with various concentrations of F1 (20%), F2 (25%), F3 (4%). Determination of antioxidant activity using the DPPH free radical immersion method. The results showed that the concentration in the granules influenced antioxidant activity with IC50 values of 109.05 ppm, 101.33 ppm and 73.28 ppm, respectively


2021 ◽  
Vol 15 (3) ◽  
pp. 1
Author(s):  
Vanessa Ferreira de Menezes ◽  
Renato Abreu Lima ◽  
Ivanir Alves da Silva ◽  
Adeilza Felipe Sampaio ◽  
Osvanda Silva de Moura

O carrapato Amblyomma cajennense é responsável por grandes perdas econômicas na pecuária bovina, principalmente nas raças de origem européia, predominantes no Sul do Brasil. Seu controle nas regiões tropicais representa um desafio devido à rápida proliferação e a resistência dos parasitas aos produtos convencionais, estimulando a busca por alternativas menos tóxicas de controle. Esse estudo teve como objetivo verificar a utilização de extratos de plantas como alternativas para carrapaticidas sintéticos. A metodologia utilizada foi realização de destilação simples dos materiais vegetais. O delineamento experimental foi o inteiramente casualizado, com cinco repetições, sendo os tratamentos constituídos pelos grupos controle negativo, água destilada e positivo, além da solução de extratos de A. occidentale, P. aduncum e M. citrifolia. Os dados foram submetidos à análise de variância e as médias comparadas pelo teste de Tukey ao nível de 5% de probabilidade do erro. Cada unidade experimental foi constituída de cinco indivíduos de A. cajennense. Para avaliar o efeito dos extratos brutos dos vegetais, foram utilizados todos os indivíduos vivos de A. cajennense coletados e classificados taxonomicamente. Os resultados encontrados mostraram que, os tratamentos mais eficientes foram: Anacardium occidentale L. e Piper aduncum L. que apresentaram eficiência de 80% e 90%, respectivamente. Porém, a eficiência mais baixa foi do Morinda citrifolia L. (20%). Os testes indicaram que Piper aduncum e Anacardium occidentale L. podem, portanto, reduzir a quantidade de carrapatos em um sistema de produção orgânica.


2021 ◽  
Vol 13 (02) ◽  
pp. 128
Author(s):  
Roikatul Miskiyah ◽  
Friska Realita

ABSTRAKLatar Belakang : Hipertensi adalah The Silent Disease sehingga seseorang tidak akan mengetahui jika dirinya menderita hipertensi atau tekanan darah tinggi. Meningkatnya tekanan darah sistolik lebih besar dari 120 mmHg dan diastolik lebih besar dari 80 mmHg pada dua kali pengukuran dengan selang waktu 5 menit dalam keadaan cukup istirahat disebut dengan Hipertensi, Hal tersebut timbul karena adanya banyak faktor interaksi resiko yang dimiliki seseorang. Tujuan : Penelitian ini bertujuan untuk menganalisis efektivitas buah mengkudu dalam menurunkan hipertensi. Metode : Pencarian artikel nasional ini dilakukan dengan basis data seperti google scohlar. Dengan kata kunci: “hipertensi”.”ekstrak buah mengkudu”. Dan penulis menemukan 7 artikel yang relevan 2014-2018. masing-masing mewakili efektivitas buah mengkudu terhadap penurunan hipertensi terhadap semua sampel.  Hasil  : Tujuh artikel yang di dapat, Menunjukkan hasil uji statistik  p Value 0,015 (p<0,05). berarti ada pengaruh antara tekanan darah siastolik maupun diastolik penderita hipertensi sebelum dan sesudah diberikan air perasan buah mengkudu. Kesimpulan : tekanan darah pada kelompok perlakuan sesudah intervensi buah mengkudu mengalami penurunan tekanan darah dibandingkan dengan kelompok control, efektivitas buah mengkudu ialah salah satu pengobatan non farmakologis.Kata kunci: Hipertensi, Ekstrak Buah MengkuduTHE EFFECTIVENESS OF NONI FRUIT (MORINDA CITRIFOLIA L.)    TO REDUCE HYPERTENSIONABSTRACTBackground : Hypertension is The Silent Disease so that a person will not know if he has hypertension or high blood pressure. Increased systolic blood pressure greater than 120 mmHg and diastolic greater than 80 mmHg in two measurements with an interval of 5 minutes in a state of sufficient rest is called Hypertension. This arises because there are many risk interaction factors that a person has. Objective : This study aims to analyze the effectiveness of noni fruit in reducing hypertension. Methods : This national article search was carried out using databases such as Google Scohlar. With keywords: "hypertension", "noni fruit extract". And the author found 7 relevant articles 2014-2018. each represents the effectiveness of noni fruit in reducing hypertension in all samples. Results : Seven articles were obtained, showing the results of the statistical test p Value of 0.015 (p <0.05). This means that there is an influence between systolic and diastolic blood pressure in patients with hypertension before and after being given noni juice. Conclusion : blood pressure in the treatment group after the noni fruit intervention decreased blood pressure compared to the control group, the effectiveness of noni fruit is one of the non-pharmacological treatments.Keywords: Hypertension, Mengkudu Fruit Extract.


Author(s):  
Syafiq Zikri Salleh ◽  
Azizah Abdul Hamid ◽  
Ahmad Haniff Jaafar ◽  
Nor Diana Abdul Majid ◽  
Nazamid Saari ◽  
...  

2021 ◽  
Author(s):  
Roisbel Aroche ◽  
Xianren Jiang ◽  
Yordan Martínez ◽  
Román Rodríguez ◽  
Xilong Li ◽  
...  

Abstract Little is known about which secondary metabolites are responsible for inhibiting pathogenic bacteria and reducing the pro-oxidant effect on the leaves of four medicinal plants used as phytobiotic in animal production. The aim of this study was to evaluate the antimicrobial and antioxidant activity of four medicinal plants (Anacardium occidentale, Psidium guajava, Morinda citrifolia and Moringa oleifera.) in vitro. A total of six bacterial strains were inoculated, then minimum bactericidal concentration (MBC) was evaluated in fine powder and minimum inhibitory concentration (MIC) and MBC were determined on the aqueous extract. Also, the in vitro antioxidant activity was evaluated through 1,1-diphenyl-2-picryl-hydrazyl, as well as the main secondary metabolites were identified and quantified by chromatographic analysis. The results showed that Anacardium occidentale and Psidium guajava leaves had higher antimicrobial activity against all bacterial strains. In addition, Morinda citrifolia inhibited S. aureus in the aqueous extract, although without in vitro bactericidal effect, while Moringa oleifera leaf did not show antimicrobial effect. All plants showed antioxidant capacity, standing out Anacardium occidentale and Psidium guajava. Mainly the leaves of Anacardium occidentale showed high concentrations of quercetin 3-O-glucoside-7-O-rhamnoside, kaempeferol-7-O-glucoside, quercetin, caffeic acid, and cinnamic acid. Apparently, the antimicrobial and antioxidant activity are due to the main polyphenolic compounds identified in medicinal plants (mainly Anacardium occidentale and Psidium guajava); however, further studies are necessary to elucidate the exact mechanism.


2021 ◽  
pp. 1-7
Author(s):  
Zhang-Yang Shen ◽  
Ying-Ying Zhao ◽  
Ze-Hua Qiao ◽  
Zhen Xie ◽  
Ruo-Qing Guan ◽  
...  

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