Distinct physiological role of amidino-TAPA-sensitive and DAMGO-insensitive μ-opioid receptor splice variants in the mouse spinal cord

2013 ◽  
Vol 711 (1-3) ◽  
pp. 80-86 ◽  
Author(s):  
Hirokazu Mizoguchi ◽  
Chizuko Watanabe ◽  
Takayuki Higashiya ◽  
Satoshi Takeda ◽  
Kaori Moriyama ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Opioid Receptor ◽  
Splice Variants ◽  
Physiological Role ◽  
Mouse Spinal Cord ◽  
Μ Opioid Receptor

Increased phosphorylated-μ-opioid receptor immunoreactivity in the mouse spinal cord following sciatic nerve ligation

2004 ◽  
Vol 354 (2) ◽  
pp. 148-152 ◽  
Author(s):  
Minoru Narita ◽  
Naoko Kuzumaki ◽  
Masami Suzuki ◽  
Michiko Narita ◽  
Kousei Oe ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Sciatic Nerve ◽  
Opioid Receptor ◽  
Mouse Spinal Cord ◽  
Μ Opioid Receptor

Role of the phosphatidylinositol-specific phospholipase C pathway in δ-opioid receptor-mediated antinociception in the mouse spinal cord

Neuroscience ◽  
2000 ◽  
Vol 99 (2) ◽  
pp. 327-331 ◽  
Author(s):  
M Narita ◽  
M Ohsawa ◽  
H Mizoguchi ◽  
T Aoki ◽  
T Suzuki ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Phospholipase C ◽  
Opioid Receptor ◽  
Mouse Spinal Cord ◽  
Δ Opioid Receptor

scholarly journals Absence of μ opioid receptor mRNA expression in astrocytes and microglia of rat spinal cord

Neuroreport ◽  
2012 ◽  
Vol 23 (6) ◽  
pp. 378-384 ◽  
Author(s):  
Sheng-Chin Kao ◽  
Xiuli Zhao ◽  
Chun-Yi Lee ◽  
Fidelis E. Atianjoh ◽  
Estelle B. Gauda ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Mrna Expression ◽  
Opioid Receptor ◽  
Rat Spinal Cord ◽  
Receptor Mrna ◽  
Μ Opioid Receptor

scholarly journals Pharmacoepigenetics of the role of DNA methylation in μ-opioid receptor expression in different human brain regions

Epigenomics ◽  
2016 ◽  
Vol 8 (12) ◽  
pp. 1583-1599 ◽  
Author(s):  
Claudia Knothe ◽  
Bruno G Oertel ◽  
Alfred Ultsch ◽  
Mattias Kettner ◽  
Peter Harald Schmidt ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Human Brain ◽  
Opioid Receptor ◽  
Brain Regions ◽  
Receptor Expression ◽  
Μ Opioid Receptor

Microglial refinement of spinal cord sensory circuitry regulates normal maturation of dynamic touch.

2021 ◽  
Author(s):  
Yajing Xu ◽  
Stephanie Koch ◽  
Alexander Chamessian ◽  
Qianru He ◽  
Mayya Sundukova ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Dorsal Horn ◽  
Normal Development ◽  
Physiological Role ◽  
Spinal Cord Dorsal Horn ◽  
Dynamic Touch ◽  
Tactile Sensitivity ◽  
Primary Afferent ◽  
Spinal Cord Dorsal

In the spinal cord dorsal horn, sensory circuits undergo remarkable postnatal reorganisation, including refinement of primary afferent A-fibres in the superficial layers, accompanied by decreased cutaneous sensitivity. Here we show a physiological role of microglia necessary for normal development of dorsal horn sensory circuits and tactile sensitivity. In the absence of microglial engulfment, superfluous A-fibre projections persist, leading to lifelong hypersensitivity to dynamic touch.

Role of Glial Cells in μ-Opioid Receptor-Mediated Vasodilation in the Rat Retina

2017 ◽  
Vol 43 (3) ◽  
pp. 350-356 ◽  
Author(s):  
Eriko Someya ◽  
Asami Mori ◽  
Daiki Asano ◽  
Akane Morita ◽  
Kenji Sakamoto ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Glial Cells ◽  
Rat Retina ◽  
Μ Opioid Receptor
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