How to read a pathology report of a bone tumor

2013 ◽  
Vol 82 (12) ◽  
pp. 2092-2099 ◽  
Author(s):  
Jean-Marc Guinebretière ◽  
Jennifer Kreshak ◽  
Voichita Suciu ◽  
Charles De Maulmont ◽  
Eric Mascard ◽  
...  
Keyword(s):  
Bone Tumor ◽  
Pathology Report

scholarly journals Analysis of X-ray Patterns in Infection and Tumor

2021 ◽  
Vol 7 (2) ◽  
Keyword(s):  
Bone Tumor ◽  
Pathology Report ◽  
Specific Diagnosis ◽  
X Ray ◽  
Ray Patterns

In diagnosis of bone tumor, X-ray is as important, if not more important than pathology report. However, X-ray had specific disadvantage. Tumor mimics especially infection can have same appearance as tumor in the X-ray. In this article, author analyzes the different patterns of X-ray changes common to tumor and infection and points outs that X-ray depicts the aggressiveness of the condition rather than a specific diagnosis

Everolimus as a Therapy of a Benign, Infiltrative Growing Bone Tumor of the Mandibula: A Rare Manifestation with Tuberous Sclerosis

2017 ◽  
Vol 48 (S 01) ◽  
pp. S1-S45
Author(s):  
B. Kauffmann ◽  
L. Günther ◽  
G. Jundt ◽  
K. Junker ◽  
O. Witt ◽  
...  
Keyword(s):  
Tuberous Sclerosis ◽  
Bone Tumor ◽  
Rare Manifestation

Integrated Approach For Bone Tumor Detection From Mri Scan Imagery

2019 ◽  
Vol 7 (4) ◽  
pp. 324-325
Author(s):  
Mrs. V.P. Krishnammal ◽  
Firosha S Fathima ◽  
Jills P Mathew ◽  
Preethi kalyani M. ◽  
V Shiva Shankari
Keyword(s):  
Bone Tumor ◽  
Integrated Approach ◽  
Tumor Detection ◽  
Mri Scan

scholarly journals Late presentation of extrauterine adenomyomas after laparoscopic morcellation at hysterectomy: a case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mohammed Nagdi Zaki ◽  
Aafia Mohammed Farooq Gheewale ◽  
Nada Ibrahim ◽  
Ibrahim Abd Elrahman
Keyword(s):  
Case Report ◽  
Transvaginal Ultrasound ◽  
Iliac Fossa ◽  
Abdominal Cavity ◽  
Laparoscopic Hysterectomy ◽  
Pathology Report ◽  
Presacral Space ◽  
Gnrh Analogue ◽  
Power Morcellation ◽  
The Right

Abstract Background An adenomyoma is a well circumscribed form of adenomyosis and can be located within the myometrium, in the endometrium as a polyp, or extrauterine with the last being the rarest presentation amongst the three. With the ongoing advancement in gynecological surgery, the use of electromechanical morcellators have made the removal of large and dense specimens possible with minimally invasive techniques. However, it has also caused an increase in complications which were previously rare. Whilst the tissue is being grinded within the abdominal cavity, residual tissue can spread and remain inside, allowing for implantation to occur and thereby giving rise to recurrence of uterine tissue as a new late postoperative complication. Case presentation A 45-year-old woman presented with worsening constipation and right iliac fossa pain. Her past surgical history consists of laparoscopic supra-cervical hysterectomy that was indicated due to uterine fibroids. Computerized tomography and magnetic resonance imaging were done, which showed an irregular lobulated heterogeneous mass seen in the presacral space to the right, located on the right lateral aspect of the recto-sigmoid, measuring 4.5 × 4.3 × 4.3 cm in size. A transvaginal ultrasound revealed a cyst in the left ovary. The patient had a treatment course over several months that included Dienogest (progestin) and Goserelin (GnRH analogue) with add-back therapy. In line with the declining response to medications, the patient was advised for a laparoscopic ovarian cystectomy. During the surgery, an additional lesion was found as a suspected fibroid and the left ovarian cyst was identified as pockets of peritoneal fluid which was sent for cytology. The surgical pathology report confirmed adenomyosis in both specimens, namely the right mass and the initially suspected fibroid. Conclusion In this case report, we showcase a rare occurrence of an extrauterine adenomyoma presenting two years post laparoscopic morcellation at hysterectomy. This poses questions regarding the benefits versus risks of power morcellation in laparoscopic hysterectomy.

scholarly journals Multisite Quality Improvement Study of a Patient-Pathologist Consultation Program

2020 ◽  
Author(s):  
Rachel Jug ◽  
Adam L Booth ◽  
Anne F Buckley ◽  
Jordan Newell ◽  
Joshua Kesterson ◽  
...  
Keyword(s):  
Quality Improvement ◽  
Health Condition ◽  
Further Education ◽  
Pathology Report ◽  
Newly Diagnosed ◽  
Patient Centered ◽  
Care Experience ◽  
Clinical Encounters ◽  
Written Information ◽  
Experience Questionnaire

Abstract Objectives The aim of this multisite quality improvement study was to evaluate patients’ experiences with the patient-centered pathology (PCP) consultation program and to determine whether PCP enhanced their care experience. Methods Patients were invited to attend PCP consultations to review their pathology report and slides and have their questions answered by the pathologist privately, with the option to attend the appointment with family members or friends for support. A patient experience questionnaire (PEQ) was administered to patients, who participated voluntarily in the PCP, and survey data were collected and stored in REDCap. Statistical analysis was performed using SAS 9.4 (SAS Institute). Results Sixty-seven patients (95.5% female) aged 18 to 84 years across 4 institutions completed the PEQ. Overall, 58% and 15.8% of patients had breast and brain tumors, respectively, and 59.7% of tumors were newly diagnosed. Most patients thought it was important for them to learn as much as they could about their health condition. However, the majority of patients reported some degree of difficulty learning about their health condition based on written information, despite 97% having completed high school and/or further education. The majority of patients rated their pathologist as “excellent” across communication metrics. Ultimately, 100% of respondents were satisfied, found their visits to be useful, and would recommend the PCP to other patients. Conclusions Patients found that personalized clinical encounters with pathologists improved their understanding of their health condition and their satisfaction with their care experience. Patients thought pathologists communicated respectfully, effectively, and empathetically.

scholarly journals Case report on metastatic pelvic bone tumor treated with frozen autograft by liquid nitrogen

2021 ◽  
Vol 82 ◽  
pp. 105910
Author(s):  
Anderson S.M. Leung ◽  
Maximus C.F. Yeung ◽  
Raymond C.H. Yau ◽  
Kenneth W.Y. Ho ◽  
Tony W.H. Shek ◽  
...  
Keyword(s):  
Case Report ◽  
Liquid Nitrogen ◽  
Bone Tumor ◽  
Pelvic Bone

scholarly journals ‘Educated’ Osteoblasts Reduce Osteoclastogenesis in a Bone-Tumor Mimetic Microenvironment

Cancers ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 263
Author(s):  
Alexus D. Kolb ◽  
Jinlu Dai ◽  
Evan T. Keller ◽  
Karen M. Bussard
Keyword(s):  
Bone Resorption ◽  
Bone Tumor ◽  
Bone Matrix ◽  
Necrosis Factor Alpha ◽  
Tumor Bearing ◽  
Receptor Activator ◽  
Factor Alpha ◽  
Osteoclast Resorption ◽  
Necrosis Factor

Breast cancer (BC) metastases to bone disrupt the balance between osteoblasts and osteoclasts, leading to excessive bone resorption. We identified a novel subpopulation of osteoblasts with tumor-inhibitory properties, called educated osteoblasts (EOs). Here we sought to examine the effect of EOs on osteoclastogenesis during tumor progression. We hypothesized that EOs affect osteoclast development in the bone-tumor niche, leading to suppressed pre-osteoclast fusion and bone resorption. Conditioned media (CM) was analyzed for protein expression of osteoclast factors receptor activator of nuclear factor kappa-β ligand (RANKL), osteoprotegerin (OPG), and tumor necrosis factor alpha (TNFα) via ELISA. EOs were co-cultured with pre-osteoclasts on a bone mimetic matrix to assess osteoclast resorption. Pre-osteoclasts were tri-cultured with EOs plus metastatic BC cells and assessed for tartrate-resistance acid phosphatase (TRAP)-positive, multinucleated (≥3 nuclei), mature osteoclasts. Tumor-bearing murine tibias were stained for TRAP to determine osteoclast number in-vivo. EO CM expressed reduced amounts of soluble TNFα and OPG compared to naïve osteoblast CM. Osteoclasts formed in the presence of EOs were smaller and less in number. Upon co-culture on a mimetic bone matrix, a 50% reduction in the number of TRAP-positive osteoclasts formed in the presence of EOs was observed. The tibia of mice inoculated with BC cells had less osteoclasts per bone surface in bones with increased numbers of EO cells. These data suggest EOs reduce osteoclastogenesis and bone resorption. The data imply EOs provide a protective effect against bone resorption in bone metastatic BC.

Bifunctional scaffolds of hydroxyapatite/poly(dopamine)/carboxymethyl chitosan with osteogenesis and anti-osteosarcoma effect

2021 ◽  
Author(s):  
Mengyu Yao ◽  
Qingxia Zou ◽  
Wenwu Zou ◽  
Zhenze Xie ◽  
Zhihao Li ◽  
...  
Keyword(s):  
Bone Tumor ◽  
Tumor Therapy ◽  
Carboxymethyl Chitosan

Bifunctional scaffolds prepared by hydroxyapatite/poly(dopamine)/carboxymethyl chitosan with good osteogenesis and anti-osteosarcoma effect is promising for bone tumor therapy.

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