scholarly journals In-hospital mortality, 30-day readmission, and length of hospital stay after surgery for primary colorectal cancer: A national population-based study

2017 ◽  
Vol 43 (7) ◽  
pp. 1312-1323 ◽  
Author(s):  
S. Pucciarelli ◽  
M. Zorzi ◽  
N. Gennaro ◽  
G. Gagliardi ◽  
A. Restivo ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Hospital Mortality ◽  
Hospital Stay ◽  
Length Of Hospital Stay ◽  
Population Based ◽  
Primary Colorectal Cancer ◽  
Population Based Study ◽  
National Population

scholarly journals Short-term postoperative outcomes of colorectal cancer among patients with chronic liver disease: a national population-based study

BMJ Open ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. e020511
Author(s):  
Ko-Chao Lee ◽  
Kuan-Chih Chung ◽  
Hong-Hwa Chen ◽  
Kung-Chuan Cheng ◽  
Kuen-Lin Wu ◽  
...  
Keyword(s):  
Liver Disease ◽  
Postoperative Complications ◽  
Colorectal Surgery ◽  
Hospital Mortality ◽  
Hospital Stay ◽  
Chronic Liver Disease ◽  
Postoperative Bleeding ◽  
Length Of Hospital Stay ◽  
Population Based ◽  
Population Based Study

ObjectivePatients with colorectal carcinoma (CRC) with pre-existing chronic liver disease (CLD) had a significantly higher 30-day mortality after CRC surgery compared with healthy controls. This study investigated the factors associated with postoperative complications and in-hospital mortality in patients with CRC with coexisting CLD (excluding cirrhosis) who underwent colorectal surgery.DesignA retrospective, observational, population-based study.SettingData were sourced from the National Inpatient Sample database, a part of the Healthcare Cost and Utilisation Project.ParticipantsThis study analysed 7463 inpatients with CRC who underwent colorectal surgery on admission between 2005 and 2014.Primary and secondary outcome measuresThe primary endpoint of this study was the prevalence of postoperative complications, and the secondary endpoint was in-hospital mortality.ResultsIn the CLD group, 36.27% of patients had chronic hepatitis C, 28.36% had non-alcoholic fatty liver disease and 31.19% had other types of CLD. The median hospital stay was 7.0 (5.0–10.0) days in patients with no postoperative complications vs 17.0 (10.0–26.0) days, 8.0 (6.0–12.0) days, 8.0 (6.0–17.0) days, 9.0 (8.0–14.0) days and 10.5 (7.0–17.0) days for patients with postoperative infection, postoperative bleeding, cardiac arrest/heart failure, respiratory complications and digestive complications, respectively (all p<0.05). The presence of CLD was significantly associated with higher risk of postoperative bleeding (adjusted OR (aOR)=1.64, 95% CI 1.15 to 2.34, p=0.007). The presence of CLD (aOR=1.98, 95% CI 1.39 to 2.82, p<0.001) and length of hospital stay (aOR=1.06, 95% CI 1.04 to 1.08, p<0.001) were significantly associated with higher risk of in-hospital mortality. However, hyperlipidaemia was associated with a significantly lower risk of mortality (aOR=0.46, 95% CI 0.28 to 0.75, p=0.002).ConclusionsPostoperative complications prolonged the length of hospital stay. The presence of CLD and hyperlipidaemia were important factors impacting postoperative complications and in-hospital mortality in patients with CRC with underlying CLD.

scholarly journals A national population-based study of incidence of colorectal cancer and age. Implications for screening in older Americans

Cancer ◽  
1995 ◽  
Vol 75 (3) ◽  
pp. 775-781 ◽  
Author(s):  
Gregory S. Cooper ◽  
Zhong Yuan ◽  
C. Seth Landefeld ◽  
John F. Johanson ◽  
Alfred A. Rimtn
Keyword(s):  
Colorectal Cancer ◽  
Population Based ◽  
Population Based Study ◽  
Older Americans ◽  
National Population

scholarly journals Plasma TIMP-1 and CEA in detection of primary colorectal cancer: a prospective, population based study of 4509 high-risk individuals

2010 ◽  
Vol 46 (1) ◽  
pp. 60-69 ◽  
Author(s):  
Hans J. Nielsen ◽  
Nils Brünner ◽  
Lars N. Jorgensen ◽  
Jesper Olsen ◽  
Hans B. Rahr ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
High Risk ◽  
Population Based ◽  
Primary Colorectal Cancer ◽  
Population Based Study

scholarly journals Path Analysis of the Impact of Obesity on Postoperative Outcomes in Colorectal Cancer Patients: A Population-Based Study

2021 ◽  
Vol 10 (13) ◽  
pp. 2904
Author(s):  
Kuan-Chih Chung ◽  
Ko-Chao Lee ◽  
Hong-Hwa Chen ◽  
Kung-Chuan Cheng ◽  
Kuen-Lin Wu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Hospital Mortality ◽  
Hospital Stay ◽  
Path Analysis ◽  
Postoperative Infection ◽  
Digestive System ◽  
Length Of Hospital Stay ◽  
Hospital Charges ◽  
Perioperative Outcomes ◽  
Total Hospital

Background: Obesity is adversely affecting perioperative outcomes; however, long-term outcomes do not appear to be affected by excess body weight (the obesity paradox). The purpose of this study is to examine the association between obesity and surgical outcomes in patients with colorectal cancer (CRC) using data from the United States National Inpatient Sample (NIS). Methods: Patients ≥20 years old diagnosed with CRC who received surgery were identified in the 2004–2014 NIS database. Patients who were obese (ICD-9-CM code: 278.0) were matched with controls (non-obese) in a 1:4 ratio for age, sex, and severity of CRC (metastasis vs. no metastasis). Linear regression and path analysis were used to compare outcomes between obese and non-obese patients. A total of 107,067 patients (53,376 males, 53,691 females) were included in the analysis, and 7.86% were obese. Results: The rates of postoperative infection, shock, bleeding, wound disruption, and digestive system complications were significantly different between the obese and non-obese groups. The obesity group had increased incidence of postoperative infection by 1.9% (∂P/∂X = 0.019), shock by 0.25% (∂P/∂X = 0.0025), postoperative bleeding by 0.5% (∂P/∂X = 0.005), wound disruption by 0.6% (∂P/∂X = 0.006), and digestive system complications by 1.35% (∂P/∂X = 0.0135). Path analysis showed that obesity group had higher in-hospital mortality through mentioned above five complications by 66.65 × 10−5%, length of hospital stay by 0.32 days, and total hospital charges by 2384 US dollars. Conclusions: Obesity increases the risk of postoperative complications in patients with CRC undergoing surgery. It also increased in-hospital mortality, length of hospital stay, and total hospital charges. Therefore, patients with obesity might require a higher level of preoperative interventions and complications monitoring to improve outcomes.

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