scholarly journals Her-2/neu overexpression in breast cancers in patients of West African extraction seen in Lagos state University Teaching hospital, Nigeria

2019 ◽  
Vol 45 (11) ◽  
pp. 2022-2025
Author(s):  
D.A. Sanni ◽  
A.O. Popoola ◽  
N.A. Ibrahim ◽  
F.O. Omodele ◽  
F.E. Emiogun ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
West African ◽  
University Teaching ◽  
Breast Cancers ◽  
State University ◽  
Lagos State ◽  
Her 2

scholarly journals Hormone Receptors and Her-2/neu Overexpression in Breast Carcinomas in Patients of West African Origin Seen at Lagos State University Teaching Hospital, Nigeria

2021 ◽  
Vol 07 (02) ◽  
pp. 076-081
Author(s):  
Daniel Ayodele Sanni ◽  
Abiodun Olaniyi Popoola ◽  
Nasiru Akanmu Ibrahim ◽  
Foluso Oyeropo Omodele ◽  
Festus Edobor Emiogun ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Carcinoma ◽  
Teaching Hospital ◽  
University Teaching ◽  
State University ◽  
Breast Carcinomas ◽  
Screening Programs ◽  
Lagos State ◽  
Her 2 ◽  
The Individual

AbstractBreast carcinoma is a disease of utmost concern to the individual, family, and society at large. The current trend in the management of breast carcinoma also involves hormonal therapy. Consequently, the hormone expression of the tumor in the individual involved must be known if he or she is to benefit from such therapy. This is a prospective study of estrogen and progesterone receptors as well as Her-2/neu overexpression in all breast carcinomas seen at the Lagos State University Teaching Hospital, Ikeja, Nigeria, between April, 1, 2016, and September, 30, 2018. The total number of cases analyzed during the period under study was 107, comprising 105 women and 2 men with an age range of 26 to 88 years and a mean age of 52 ± 13 years. The tumors fell into histologic grade II (71.0%) and grade III (29.0%). They expressed ER, PR, and Her-2/neu positivity in 42.1%, 33.6%, and 30.8% of the cases, respectively. Triple-negative breast cancer was 35.5%. Male breast cancers presented as invasive ductal carcinoma and exhibit similar staining pattern as the female breast cancer. In conclusion, this study shows that breast carcinomas occurred predominantly in females of younger age and present with tumors, most of which were of high grade and exhibit triple negativity. This observation is relevant to any therapeutic decisions and management of these patients. Improvement in breast carcinoma screening programs so that the disease can be detected early is also advocated.

scholarly journals Comparison of two different forms of varnishes in the treatment of dentine hypersensitivity: A subject-blind clinical study in Lagos State university teaching hospital

2017 ◽  
Vol 5 (2) ◽  
pp. 191
Author(s):  
Afolabi Oyapero ◽  
OmotolaEnere Owoturo ◽  
AdolphousOdogun Loto ◽  
AdenikeOlolade Awotile ◽  
SylvanusO Ebigwei
Keyword(s):  
Clinical Study ◽  
Teaching Hospital ◽  
University Teaching ◽  
State University ◽  
Dentine Hypersensitivity ◽  
Lagos State

scholarly journals Ferritin and transferrin levels of the elderly population at Lagos State university teaching hospital, Ikeja, Lagos, Nigeria

2021 ◽  
Vol 7 (12) ◽  
pp. 559
Author(s):  
Abdulateef O. Kareem ◽  
Akinsegun A. Akinbami ◽  
Ebele I. Uche ◽  
Aishatu M. Suleiman ◽  
Rafah A. Bamiro ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Serum Ferritin ◽  
Teaching Hospital ◽  
Blood Count ◽  
The Elderly ◽  
University Teaching ◽  
Full Blood Count ◽  
State University ◽  
Lagos State ◽  
The Mean

<p class="abstract"><strong>Background:</strong> The elderly have limited regenerative abilities thus predisposing them to various diseases. Measuring both serum ferritin and transferrin serve as biomarkers of iron deficiency. This study, using enzyme-linked immunosorbent assay (ELISA) determined the serum levels of ferritin and transferrin in the elderly. Full blood count was also done and correlated with serum ferritin and transferrin levels of every participant.</p><p class="abstract"><strong>Methods:</strong> This was a cross-sectional study at the Geriatric Clinic of Lagos State University Teaching Hospital (LASUTH). Following receipt of written consents from ninety (90) elderly participants, venous samples were drawn for full blood count (FBC) and samples for serum ferritin and transferrin ELISA assay collected and stored at -40<sup>o</sup>C until the required sample size was obtained. Data were analyzed using SPSS version 23.0 (Statistical Package for Social Sciences, Inc., Chicago, Ill). The Pearson chi-square test was used for statistical analysis. P value was considered to be statistically significant when &lt;0.05.  </p><p class="abstract"><strong>Results:</strong> Participants consisted of 50 (55.6%) females and 40 (44.4%) males. The mean age of all participants was 71.31±7.38 years. The Majority, 90% (36 of 40) of the males had haemoglobin values lower than 13 gm/dl, while 66% (33 of 50) of females had haemoglobin values lower than 12 gm/dl. The mean ferritin concentration of all participants was 196.19 ±121.21ng/ml. The overall mean serum transferrin was 0.187±0.157 ng/ml with a minimum of 0.03 ng/ml and a maximum of 1.18 ng/ml.</p><p class="abstract"><strong>Conclusions:</strong> Anaemia in the elderly is very common using the World Health Organization (WHO) haemoglobin cut-off values, however, iron deficiency anaemia prevalence is low.</p>

Penile Injuries In Lagos State University Teaching Hospital Ikeja: A 7-year Experience

2015 ◽  
Vol 6 (1) ◽  
pp. 22
Author(s):  
MJ Bioku ◽  
AA Abolarinwa ◽  
SF Ahmad ◽  
FO Oladepo ◽  
OA Omisanjo ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
University Teaching ◽  
State University ◽  
Lagos State
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