scholarly journals Seroprevalence of Toxoplasma gondii antibodies amongst pregnant women at Lagos State University Teaching Hospital

2010 ◽  
Vol 14 ◽  
pp. e288 ◽  
Author(s):  
A. Akinbami
Keyword(s):  
Toxoplasma Gondii ◽  
Pregnant Women ◽  
Teaching Hospital ◽  
University Teaching ◽  
State University ◽  
Lagos State

scholarly journals Prevalence and Demographic Correlates of Seropositive HIV and HBsAg Cases among Women Booking for Antenatal Care at the Rivers State University Teaching Hospital, Nigeria

2019 ◽  
pp. 1-9
Author(s):  
P. A. Awoyesuku ◽  
D. A. Macpepple ◽  
B. O. Altraide ◽  
D. H. John
Keyword(s):  
Pregnant Women ◽  
Teaching Hospital ◽  
Educational Status ◽  
University Teaching ◽  
P Value ◽  
Seroprevalence Rate ◽  
State University ◽  
Global Public Health ◽  
The Mean ◽  
Rivers State

Background: Infection with hepatitis B (HBV) and human immunodeficiency virus (HIV) are global public health problems. These infections during pregnancy increase the risk of maternal morbidity and mortality, and also pose a risk to the fetus due to mother to child transmission. Objective: To determine the prevalence of seropositive HIV and HBsAg cases amongst pregnant women at the Rivers State University Teaching Hospital (RSUTH). Methodology: A retrospective review of hospital and laboratory records of all pregnant women booked at RSUTH in two years, from May 2017 to April 2019, was carried out. Data on patients’ age, parity and educational level and reactivity of HIV and HBsAg test at booking were retrieved using structured proforma and analyzed using Epi Info Version 7. Test for significance using Chi-square was set at a significant level of P<0.05. Results: 3560 patients had HIV and HBsAg screening out of which 148 (4.2%) and 9 (0.3%) respectively were positive. The comorbidity rate in this study was 0.06%. The mean age was 31.5±4.7 years and the mean gestational age at booking was 22.1±6.8 weeks. There was no significant relationship between their age (χ2 = 2.690, p-value=0.442) and parity (χ2 = 3.759, p-value = 0.145) with HIV seropositivity, but these were significant for HBsAg (χ2 = 13.691, p-value = 0.003) (χ2 = 13.121, p-value=0.001).  Educational status was significant for HIV (χ2 = 16.188, p-value=0.000) but not for HBsAg (χ2 = 0.229, p-value=0.892). Conclusion: The seroprevalence rate of HIV and HBsAg in this study were low. HIV seroprevalence was significantly affected by lower education, while HBsAg seroprevalence was significantly affected by younger maternal age and nulliparity. Continued screening of pregnant women for these infections remains valuable and further community-based studies to identify risk factors are recommended.

scholarly journals Prevalence of Seropositive VDRL Cases amongst Pregnant Women at the Rivers State University Teaching Hospital, Nigeria: Is Routine Screening for Syphilis Using VDRL Still Relevant?

2019 ◽  
pp. 1-7
Author(s):  
P. A. Awoyesuku ◽  
D. A. MacPepple ◽  
N. J. Kwosah
Keyword(s):  
Pregnant Women ◽  
Teaching Hospital ◽  
University Teaching ◽  
P Value ◽  
Seroprevalence Rate ◽  
State University ◽  
Serological Screening ◽  
Specific Test ◽  
The Mean ◽  
Rivers State

Background: Untreated maternal syphilis is strongly associated with adverse birth outcomes. The WHO recommends routine serological screening in pregnancy. Some workers have advised a reappraisal of this practice, having demonstrated low seroprevalence in their antenatal population. Objective: To determine the prevalence of seropositive VDRL cases amongst pregnant women at the Rivers State University Teaching Hospital (RSUTH) in order to justify the need and cost-effectiveness for continued routine syphilis screening using VDRL alone. Methodology: A retrospective review of hospital and laboratory records of all pregnant women booked for antenatal care (ANC) at RSUTH in a two-year period, from May 2017 to April 2019, was carried out. Data on patients’ age, parity and educational level, and reactivity of VDRL test at booking were retrieved using structured pro-forma and analyzed using Epi Info Version 7. Test for significance using Chi-square was set at significant level of P<0.05. Results: 3560 clinic patients had VDRL screening out of which 63 were positive. The overall prevalence rate in this study was 1.8%. The mean age was 31.5±4.7 years and the mean gestational age at booking was 22.1±6.8 weeks. There was no significant relationship between their age (χ2 = 0.403, p-value=0.940), parity (χ2 = 3.707, p-value=0.0.157), and educational status (χ2 = 1.853, p-value=0.396), and seropositivity. The cost of VDRL test per patient in RSUTH is $3, to detect the 63 cases the sum of $10,680 was spent. Conclusion: The seroprevalence rate of syphilis in this study was low. Initial screening using VDRL alone is neither justified nor cost effective. Selective screening based on risk factors and specific test with TPHA is recommended.

scholarly journals Ferritin and transferrin levels of the elderly population at Lagos State university teaching hospital, Ikeja, Lagos, Nigeria

2021 ◽  
Vol 7 (12) ◽  
pp. 559
Author(s):  
Abdulateef O. Kareem ◽  
Akinsegun A. Akinbami ◽  
Ebele I. Uche ◽  
Aishatu M. Suleiman ◽  
Rafah A. Bamiro ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Serum Ferritin ◽  
Teaching Hospital ◽  
Blood Count ◽  
The Elderly ◽  
University Teaching ◽  
Full Blood Count ◽  
State University ◽  
Lagos State ◽  
The Mean

<p class="abstract"><strong>Background:</strong> The elderly have limited regenerative abilities thus predisposing them to various diseases. Measuring both serum ferritin and transferrin serve as biomarkers of iron deficiency. This study, using enzyme-linked immunosorbent assay (ELISA) determined the serum levels of ferritin and transferrin in the elderly. Full blood count was also done and correlated with serum ferritin and transferrin levels of every participant.</p><p class="abstract"><strong>Methods:</strong> This was a cross-sectional study at the Geriatric Clinic of Lagos State University Teaching Hospital (LASUTH). Following receipt of written consents from ninety (90) elderly participants, venous samples were drawn for full blood count (FBC) and samples for serum ferritin and transferrin ELISA assay collected and stored at -40<sup>o</sup>C until the required sample size was obtained. Data were analyzed using SPSS version 23.0 (Statistical Package for Social Sciences, Inc., Chicago, Ill). The Pearson chi-square test was used for statistical analysis. P value was considered to be statistically significant when &lt;0.05.  </p><p class="abstract"><strong>Results:</strong> Participants consisted of 50 (55.6%) females and 40 (44.4%) males. The mean age of all participants was 71.31±7.38 years. The Majority, 90% (36 of 40) of the males had haemoglobin values lower than 13 gm/dl, while 66% (33 of 50) of females had haemoglobin values lower than 12 gm/dl. The mean ferritin concentration of all participants was 196.19 ±121.21ng/ml. The overall mean serum transferrin was 0.187±0.157 ng/ml with a minimum of 0.03 ng/ml and a maximum of 1.18 ng/ml.</p><p class="abstract"><strong>Conclusions:</strong> Anaemia in the elderly is very common using the World Health Organization (WHO) haemoglobin cut-off values, however, iron deficiency anaemia prevalence is low.</p>

scholarly journals Her-2/neu overexpression in breast cancers in patients of West African extraction seen in Lagos state University Teaching hospital, Nigeria

2019 ◽  
Vol 45 (11) ◽  
pp. 2022-2025
Author(s):  
D.A. Sanni ◽  
A.O. Popoola ◽  
N.A. Ibrahim ◽  
F.O. Omodele ◽  
F.E. Emiogun ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
West African ◽  
University Teaching ◽  
Breast Cancers ◽  
State University ◽  
Lagos State ◽  
Her 2
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