scholarly journals Assessment of Plasma Oxalate Concentration in Patients With CKD

2020 ◽  
Vol 5 (11) ◽  
pp. 2013-2020
Author(s):  
Anja Pfau ◽  
Monika Wytopil ◽  
Kinsuk Chauhan ◽  
Martin Reichel ◽  
Steve G. Coca ◽  
...  
2021 ◽  
Vol 6 (4) ◽  
pp. 1194-1195
Author(s):  
Anja Pfau ◽  
Monika Wytopil ◽  
Kinsuk Chauhan ◽  
Martin Reichel ◽  
Steve Coca ◽  
...  

Author(s):  
Elena Yusenko ◽  
Evgeniya Polyntseva ◽  
Anna Lyzhova ◽  
Olga Kalyakina

Abstract Oxalate concentration differs in various daily consumed food products. The role of oxalic acid in the human body is very significant, as its compounds are responsible for the stability of biological membranes. However, insoluble calcium and magnesium oxalates can be accumulated in the body in the form of kidney stones. Oxalate concentration has been measured by high performance liquid, gas after derivatization and ion chromatography (IC). The most effective method for the simultaneous determination of oxalate and inorganic anions is ion chromatography with conductometric detection. Here, we report the results of the measurement of oxalic acid in bleak and green tea samples. Separation was performed by IC on an anion-exchange column Shodex IC SI-90 with surface-layer sorbent and conductimetric detection. The main analytical features of the method were: limit of detection of oxalic acid 0.03 mg/l, linear range 0.1-20 mg/l, correlation 0.9998, relative standard deviation 1%. The method did not need specific sample treatment and was successfully applied to the analysis of black and green tea samples. Oxalic acid was determined in the ranges 16.7-84 mg/l for green tea and 63-116 mg/l for black tea. Green tea contained lower oxalate ions concentration than black tea. The IC method has a lower detection limit for oxalate ions than HPLS and GC, ten and two times less, respectively


1981 ◽  
Vol 240 (4) ◽  
pp. F295-F298 ◽  
Author(s):  
T. F. Knight ◽  
S. C. Sansom ◽  
H. O. Senekjian ◽  
E. J. Weinman

Simultaneous capillary and luminal microperfusion studies in the proximal convoluted tubule of the rat were performed to examine the transepithelial secretory flux of [14C]oxalate. Increases in the concentration of oxalate in the capillary solution from 0.096 to 4.3 mM resulted in progressively higher rates of oxalate secretion into the lumen. Further increases in the capillary concentration of oxalate indicated a tendency toward a plateau. The inclusion of para-chloromercuribenzoate, sodium cyanide, indanyloxyacetic acid, furosemide, or para-aminohippurate in the capillary solution significantly lowered the secretory flux of oxalate. the addition of probenecid in a concentration of 10(-4) M inhibited oxalate secretion when the oxalate concentration in the capillary solution ranged between 1.1 and 4.3 mM, but did not affect oxalate secretion at higher capillary concentrations of oxalate. These results indicate that oxalate secretion in the rat proximal tubule is an active carrier-mediated process. When considered in conjunction with prior studies, the present investigations suggest the possibility that more than one oxalate secretory system exists in the rat proximal tubule.


1985 ◽  
Vol 69 (1) ◽  
pp. 87-90 ◽  
Author(s):  
R. W. E. Watts ◽  
N. Veall ◽  
P. Purkiss ◽  
M. A. Mansell ◽  
E. F. Haywood

1. We have measured glomerular filtration rate (GFR), extracellular fluid volume (ECF), oxalate distribution volume (OxDV), plasma oxalate concentration (POx.), plasma total clearance of oxalate (PCOx.), oxalate metabolic pool size [(OxDV) × (POx.)], renal clearance of oxalate (RCOx.), oxalate excretion, tissue clearance of oxalate (TCOx.) and tissue oxalate accumulation rate [(TOx.A) = (TCOx.) × (POx.)] in three patients with type I primary hyperoxaluria (hyperoxaluria with hypergrycollic aciduria) when they were taking pyridoxine and after discontinuation of the vitamin. 2. Seven days after stopping pyridoxine the plasma oxalate concentration, oxalate metabolic pool size and the urinary excretion of oxalate had all increased between seven- and eight-fold in two of the patients. The third patient showed no changes on stopping pyridoxine. 3. These results support the view that pyridoxine acts by reducing oxalate biosynthesis in some patients with type I primary hyperoxaluria. 4. The possible biochemical basis for this effect is discussed.


1972 ◽  
Vol 12 (57) ◽  
pp. 400 ◽  
Author(s):  
RJ Jones ◽  
CW Ford

The effect of urea on the oxalate concentration of Setaria sphacelata CV. Kazungula was studied in three field experiments. In the first experiment conducted in autumn, urea increased oxalate and cation concentration, and the relation between oxalate and cation concentration was linear (r = 0.90). In the second experiment conducted over autumn and spring, there was a trend of increasing oxalate concentration with urea rate and a decline with age of plant material. However, in autumn regrowths, urea reduced the oxalate in young regrowth (to two weeks) but in older regrowths urea increased oxalate to a peak of 6.0 per cent in the dry matter. A third experiment confirmed the increased oxalate concentration following urea fertilization and also an effect of potassium at a high rate, especially when applied as KCl. The ranking of the plant parts for oxalate was-leaf blades > leaf sheaths > stems. No oxalate was detected in the seed heads. Urea increased the oxalate content of leaf sheaths and particularly of stems, but had less effect on the content in leaf blades. A diurnal trend in oxalate content of tillers occurred in both the high oxalate cultivar Kazungula and in the low oxalate cultivar Nandi. Of the total oxalate present, 90 per cent was water soluble. No ammonium oxalate was detected but both sodium oxalate and potassium oxalate were isolated from setaria. The high excess cation concentration in Setaria is probably the reason for the high levels of oxalate encountered with this grass.


1984 ◽  
Vol 4 (2) ◽  
pp. 118-122 ◽  
Author(s):  
Peter Boer ◽  
Leo van Leersum ◽  
Ronald J. Hené ◽  
Evert J. Dorhout Mees

1988 ◽  
Vol 75 (s19) ◽  
pp. 53P-53P
Author(s):  
CRV Tomson ◽  
SM Channon ◽  
WL Sheldon ◽  
IS Parkinson ◽  
MK Ward ◽  
...  

HortScience ◽  
1994 ◽  
Vol 29 (9) ◽  
pp. 1019-1021 ◽  
Author(s):  
I. Okutani ◽  
N. Sugiyama

A negative relationship has been reported between the oxalate concentration in leaves and leaf position numbered from the base for `Okame' spinach (Spinacia oleracea L.). We compared changes in leaf and stem oxalate concentrations among three cultivars. `Viroflay' differentiated and developed leaves at a lower rate than did `Okame' and `Kyoho'. Oxalate concentrations in plant tops decreased with time in `Okame' and `Kyoho', but `Viroflay' changed little. The relationship between leaf oxalate concentration (Y; millimoles per gram of fresh weight) and its position on the stem (X) was the same for all cultivars and can be given as Y = -0.0089X + 0.158.


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