Swelling ratio driven changes of probe concentration in pH- and ionic strength-sensitive poly(acrylic acid) hydrogels

2009 ◽  
Vol 11 (6) ◽  
pp. 1217-1220 ◽  
Author(s):  
Marcin Karbarz ◽  
Wojciech Hyk ◽  
Zbigniew Stojek
Keyword(s):  
Ionic Strength ◽  
Acrylic Acid ◽  
Swelling Ratio ◽  
Probe Concentration ◽  
Poly Acrylic Acid

Determination of the complexation properties of a crosslinked poly(acrylic acid) gel with copper(II), nickel(II), and lead(II) in dilute aqueous solution

2001 ◽  
Vol 79 (4) ◽  
pp. 370-376 ◽  
Author(s):  
Catherine Morlay ◽  
Yolande Mouginot ◽  
Monique Cromer ◽  
Olivier Vittori
Keyword(s):  
Aqueous Solution ◽  
Ionic Strength ◽  
Acrylic Acid ◽  
Metal Ion ◽  
Conditional Stability ◽  
Binding Properties ◽  
Complex Species ◽  
Complexing Capacity ◽  
Dilute Aqueous Solution ◽  
Poly Acrylic Acid

The possible removal of copper(II), nickel(II), or lead(II) by an insoluble crosslinked poly(acrylic acid) was investigated in dilute aqueous solution. The binding properties of the polymer were examined at pH = 6.0 or 4.0 with an ionic strength of the medium µ = 0.1 or 1.0 M (NaNO3) using differential pulse polarography as an investigation means. The highest complexing capacity of the polyacid was obtained with lead(II) at pH = 6.0 with µ = 0.1 M, 4.8 mmol Pb(II)/g polymer. The conditional stability constants of the complex species formed were determined using the method proposed by Ruzic assuming that only the 1:1 complex species was formed; for lead(II) at pH = 6.0 and µ = 0.1 M, log K' = 5.3 ± 0.2. It appeared that the binding properties of the polymer increased, depending on the metal ion, in the following order: Ni(II) < Cu(II) < Pb(II). The complexing capacity and log K' values decreased with the pH or with an increase of the ionic strength. These results were in agreement with the conclusions of our previous studies of the hydrosoluble linear analogues. Finally, with the insoluble polymer, the log K' values were comparable to those previously obtained with the linear analogue whereas the complexing capacity values expressed in mmol g-1 were slightly lower.Key words: insoluble crosslinked poly(acrylic acid), copper(II), nickel(II), and lead(II) complexation.

Structure and swelling of poly(acrylic acid) hydrogels: effect of pH, ionic strength, and dilution on the crosslinked polymer structure

Polymer ◽  
2004 ◽  
Vol 45 (5) ◽  
pp. 1503-1510 ◽  
Author(s):  
Jeannine E. Elliott ◽  
Mara Macdonald ◽  
Jun Nie ◽  
Christopher N. Bowman
Keyword(s):  
Ionic Strength ◽  
Acrylic Acid ◽  
Polymer Structure ◽  
Effect Of Ph ◽  
Crosslinked Polymer ◽  
Poly Acrylic Acid

scholarly journals Development and Characterization of Cross-Linked Poly(acrylic acid) Hydrogel Containing Drug by Radiation-Based Techniques

2018 ◽  
Author(s):  
Jin-Oh Jeong ◽  
Jae Baik ◽  
Sung-Jun An ◽  
Sung-In Jeong ◽  
Jae-Young Lee ◽  
...  
Keyword(s):  
Acrylic Acid ◽  
Cross Linking ◽  
Radiation Doses ◽  
Swelling Ratio ◽  
Chemical Additives ◽  
Drug Delivery Carrier ◽  
Radiation Induced ◽  
Crystalline Nature ◽  
Poly Acrylic Acid

Poly(acrylic acid) (PAAc) hydrogels possess good bioadhesive properties and allow enhanced penetration of drugs. In addition, it is possible to localize the absorption site of the drug in the hydrogel and increase the drug residence time. As opposed to other cross-linking processes radiation-induced polymer cross-linking can be easily and rapidly carried out without the use of cross-linking agents and other chemical additives. In this study, we fabricated metronidazole (MD) containing PAAc hydrogel (MD/PAAc) with different MD contents (0.1, 0.25, 0.5 wt%) using varying radiation doses (25, 50, 75 kGy) by gamma-irradiation. The physical and thermal properties were determined by gel content analysis, swelling ratio measurements, compressive strength measurements, differential scanning calorimetery, and thermogravimetric analysis. The properties of the hydrogel degraded due to the crystalline nature of MD. The properties of the hydrogel degraded due to the crystalline nature of MD. Cumulative release observed after 50 min in the case of 0.5MD/PAAc and 0.1MD/PAAc was 50% and 10%, respectively. Our findings suggest that MD/PAAc could be a suitable drug delivery carrier for use with radiation-based techniques.

Synthesis and Characteristics of Interpenetrating Polymer Network Hydrogels Based on Konjac Glucomannan with Different Molecular Weights and Poly(acrylic acid)

2011 ◽  
Vol 393-395 ◽  
pp. 1004-1007
Author(s):  
Xue Yao ◽  
Xue Gang Luo ◽  
Ben Chao Han
Keyword(s):  
Acrylic Acid ◽  
Enzymatic Degradation ◽  
Drug Carrier ◽  
Polymer Network ◽  
Konjac Glucomannan ◽  
Interpenetrating Polymer Network ◽  
Swelling Ratio ◽  
Molecular Weights ◽  
Ft Ir ◽  
Poly Acrylic Acid

Konjac glucomannan with different molecular weights/poly(acrylic acid) hydrogels were prepared in this paper. The structure of the IPN hydrogels was characterized by FT-IR and SEM. The swelling ratio of these hydrogels showed they had pH-sensitive properties and the enzymatic degradation tests showed the hydrogels retain the enzymatic degradation character of KGM. Furthermore, hydrogel composed of native KGM degraded sharply in enzymatic degradation test and it had bigger swelling ratio and weight loss ratio than those hydrogels which composed of lower molecular weights KGM. Therefore, hydrogels composed of lower molecular weight might release drug more stable when they were used as drug carrier.

pH- and Ionic-Strength-Induced Structural Changes in Poly(acrylic acid)-Lipid-Based Self-Assembled Materials

2009 ◽  
Vol 281 (1) ◽  
pp. 126-134 ◽  
Author(s):  
Anthony Crisci ◽  
Daniel N. T. Hay ◽  
Sönke Seifert ◽  
Millicent A. Firestone
Keyword(s):  
Ionic Strength ◽  
Acrylic Acid ◽  
Structural Changes ◽  
Self Assembled ◽  
Poly Acrylic Acid
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