scholarly journals Regenerative Engineering for Knee Osteoarthritis Treatment: Biomaterials and Cell-Based Technologies

Engineering ◽  
2017 ◽  
Vol 3 (1) ◽  
pp. 16-27 ◽  
Author(s):  
Jorge L. Escobar Ivirico ◽  
Maumita Bhattacharjee ◽  
Emmanuel Kuyinu ◽  
Lakshmi S. Nair ◽  
Cato T. Laurencin
Keyword(s):  
Knee Osteoarthritis ◽  
Regenerative Engineering ◽  
Osteoarthritis Treatment

scholarly journals Pharmacological approach of knee osteoarthritis treatment in primary care in spain

2017 ◽  
Vol 25 ◽  
pp. S204
Author(s):  
M. Herrero ◽  
S. Gimenez ◽  
J. Vergara ◽  
E. Viles ◽  
H. Martinez ◽  
...  
Keyword(s):  
Primary Care ◽  
Knee Osteoarthritis ◽  
Pharmacological Approach ◽  
Osteoarthritis Treatment

scholarly journals Manfaat Proloterapi pada Osteoartritis Lutut

e-CliniC ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Gracia V. Y. Deeng ◽  
Sekplin A. S. Sekeon ◽  
Finny Warouw
Keyword(s):  
Knee Osteoarthritis ◽  
Immune Cells ◽  
Joint Instability ◽  
Inflammatory Cells ◽  
Cartilage Destruction ◽  
The Body ◽  
The Other ◽  
Vigorous Exercise ◽  
Painful Sensation ◽  
Osteoarthritis Treatment

Abstract: Osteoarthritis (OA) is calcification of the joint associated with severe painful sensation caused by joint instability. This joint instability is affected by destruction of cartilage that protects the bones. Osteoarthritis can be caused by various factors such as age, genetic as well as vigorous exercise or activity. As the cartilage destruction progresses, the unprotected bone will rub on the other bone in the joint which can lead to osteoarthritis. Management of OA consists of a variety of treatments, such as pharmacological, non-pharmacological, non-pharmacotherapy, and surgery treatments. Due to the development of science and technology, various modalities have emerged that can support the treatment of OA inter alia prolotherapy. Prolotherapy or regenerative injection could influence the recovery of the destructed area directly and relief the painful sensation through the actions of inflammatory cells, macrophages, immune cells, and cytokines, therefore, the improvement of the destructed areas could occur faster. It was reported that knee osteoarthritis could be treated with prolotherapy successfully. In conclusion, since prolotherapy influences the body to repair the destructed areas, hence it could be used as the new osteoarthritis treatment, especially knee osteoarthritis.Keywords: prolotherapy, knee osteoarthritis, chronic pain Abstrak: Osteoartritis (OA) merupakan pengapuran sendi yang disertai nyeri hebat, disebabkan oleh karena adanya ketidakstabilan sendi yang dipengaruhi oleh rusaknya tulang rawan yang berperan untuk melindungi tulang. Osteoartritis dapat disebabkan oleh berbagai faktor seperti usia, jenis kelamin, genetik, aktivitas maupun olahraga berat. Saat tulang rawan rusak, maka tulang yang tidak dilindungi dapat saling bersinggungan di sendi sehingga sendi hancur dan berujung pada OA. Pengobatan untuk OA terdiri dari beragam pengobatan baik farmakologi, non-farmakologi, non-farmakoterapi, maupun tindakan operasi. Seiring berjalannya perkembangan ilmu pengetahuan dan teknologi, maka muncul berbagai modalitas yang dapat menunjang pengobatan OA, antara lain proloterapi. Proloterapi atau injeksi regeneratif memengaruhi dan memberi dampak penyembuhan secara langsung pada area yang mengalami cedera maupun nyeri melalui kerja sel-sel radang, makrofag, sel-sel imun, dan sitokin sehingga dapat bekerja lebih cepat untuk perbaikan daerah yang cedera. Telah dilaporkan hasil bermakna dalam peng-gunaan proloterapi pada osteoartritis lutut. Simpulan penelitian ini ialah proloterapi merangsang tubuh untuk memperbaiki daerah yang cedera sehingga merupakan solusi terbaik yang dibutuhkan dalam pengobatan OA dewasa ini terutama pada OA lutut.Kata kunci: proloterapi, osteoartritis lutut, nyeri kronik

Different Strategies in Knee Osteoarthritis Treatment

2019 ◽  
Author(s):  
Maxim A. Korolev ◽  
Yuliya D. Kurochkina ◽  
Elena A. Letyagina ◽  
Nadezda E. Banshikova ◽  
Vitaliy O. Omelchenko ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Osteoarthritis Treatment

scholarly journals Decision Aid Implementation and Patients’ Preferences for Hip and Knee Osteoarthritis Treatment: Insights from the High Value Healthcare Collaborative

2020 ◽  
Vol Volume 14 ◽  
pp. 23-32
Author(s):  
Vanessa B Hurley ◽  
Yue Wang ◽  
Hector P Rodriguez ◽  
Stephen M Shortell ◽  
Stephen Kearing ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Decision Aid ◽  
Osteoarthritis Treatment

Haptic gait retraining for knee osteoarthritis treatment

2010 ◽  
Author(s):  
Pete Shull ◽  
Kristen Lurie ◽  
Mihye Shin ◽  
Thor Besier ◽  
Mark Cutkosky
Keyword(s):  
Knee Osteoarthritis ◽  
Gait Retraining ◽  
Osteoarthritis Treatment

scholarly journals Platelet-rich plasma in knee osteoarthritis treatment

2015 ◽  
Vol 83 (4) ◽  
pp. 352-358
Author(s):  
Mario Alberto Simental-Mendía ◽  
José Félix Vílchez-Cavazos ◽  
Herminia Guadalupe Martínez-Rodríguez
Keyword(s):  
Knee Osteoarthritis ◽  
Platelet Rich Plasma ◽  
Osteoarthritis Treatment

Comparative effects of combined physical therapy with Kinesio taping and physical therapy in patients with knee osteoarthritis: a systematic review and meta-analysis

2020 ◽  
Vol 34 (8) ◽  
pp. 1014-1027
Author(s):  
Chia-Hung Lin ◽  
Meng Lee ◽  
Kuan-Yu Lu ◽  
Chia-Hao Chang ◽  
Shih-Shin Huang ◽  
...  
Keyword(s):  
Physical Therapy ◽  
Knee Osteoarthritis ◽  
Rating Scale ◽  
Pain Reduction ◽  
Functional Improvement ◽  
Controlled Trials ◽  
Therapeutic Effects ◽  
Cochrane Central Register ◽  
Kinesio Taping ◽  
Osteoarthritis Treatment

Objective: To compare therapeutic effects between physical therapy (PT) combined with Kinesio taping (KT) and PT alone in knee osteoarthritis treatment. Data sources: PubMed, Embase, MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, Scopus, CNKI, WangFang Data, and Google Scholar were searched until 16 April 2020. Review methods: Randomized controlled trials comparing pain reduction (visual analogue scale and numeric pain rating scale) and functional improvement (Western Ontario and McMaster Universities Osteoarthritis Index) between PT + KT and PT in knee osteoarthritis treatment were included. The risk of bias was assessed using the Cochrane Collaboration’s tool. Results: A total of 15 studies with 546 patients were included, and their outcomes for one to six weeks after initial treatments were compared. An overall trend favoring PT + KT over PT alone was indicated by greater pain score reduction (mean difference (MD) = −0.70, 95% confidence interval (CI) = −1.14 to −0.26; P = 0.002) and functional improvement (MD = −5.45, 95% CI = −10.23 to −0.66; P = 0.03) with the former. Significant pain reduction (MD = −0.72, 95% CI = −1.18 to −0.26; P = 0.002) and functional improvement (MD = −6.05, 95% CI = −11.18 to −0.93; P = 0.02) were reported within six weeks after initial treatments. Conclusion: Compared with PT alone, PT combined with KT provided better therapeutic effect regarding pain reduction and functional improvement in patients with knee osteoarthritis. The additional pain reduction and functional improvement could last at least six weeks after initial treatments.

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