Retrospective study of foreign body-associated pathology in stranded cetaceans, Canary Islands (2000–2015)

2018 ◽  
Vol 243 ◽  
pp. 519-527 ◽  
Author(s):  
R. Puig-Lozano ◽  
Y. Bernaldo de Quirós ◽  
J. Díaz-Delgado ◽  
N. García-Álvarez ◽  
E. Sierra ◽  
...  
2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Prashant Hariharan ◽  
Jeffrey Sondheimer ◽  
Alexandra Petroj ◽  
Jacob Gluski ◽  
Andrew Jea ◽  
...  

Abstract Background Implantation of ventricular catheters (VCs) to drain cerebrospinal fluid (CSF) is a standard approach to treat hydrocephalus. VCs fail frequently due to tissue obstructing the lumen via the drainage holes. Mechanisms driving obstruction are poorly understood. This study aimed to characterize the histological features of VC obstructions and identify links to clinical factors. Methods 343 VCs with relevant clinical data were collected from five centers. Each hole on the VCs was classified by degree of tissue obstruction after macroscopic analysis. A subgroup of 54 samples was analyzed using immunofluorescent labelling, histology and immunohistochemistry. Results 61.5% of the 343 VCs analyzed had tissue aggregates occluding at least one hole (n = 211) however the vast majority of the holes (70%) showed no tissue aggregates. Mean age at which patients with occluded VCs had their first surgeries (3.25 yrs) was lower than in patients with non-occluded VCs (5.29 yrs, p < 0.02). Mean length of time of implantation of occluded VCs, 33.22 months was greater than for non-occluded VCs, 23.8 months (p = 0.02). Patients with myelomeningocele had a greater probability of having an occluded VC (p = 0.0426). VCs with occlusions had greater numbers of macrophages and astrocytes in comparison to non-occluded VCs (p < 0.01). Microglia comprised only 2–6% of the VC-obstructing tissue aggregates. Histologic analysis showed choroid plexus occlusion in 24%, vascularized glial tissue occlusion in 24%, prevalent lymphocytic inflammation in 29%, and foreign body giant cell reactions in 5% and no ependyma. Conclusion Our data show that age of the first surgery and length of time a VC is implanted are factors that influence the degree of VC obstruction. The tissue aggregates obstructing VCs are composed predominantly of astrocytes and macrophages; microglia have a relatively small presence.


Pulmonology ◽  
2018 ◽  
Vol 24 (1) ◽  
pp. 50-52 ◽  
Author(s):  
C. Costa ◽  
S. Feijó ◽  
P. Monteiro ◽  
L. Martins ◽  
J.Rosal. Gonçalves

2021 ◽  
pp. 67-68
Author(s):  
Poornima Kumar ◽  
Sudhagar Eswaran

Mechanism of entry of foreign body into nasopharynx can sometimes be confusing and is easily overlooked in the routine foreign body workup and acts as a hidden area for vanishing foreign bodies. Authors emphasize the importance of parental education and awareness to avoid digital manipulation/extraction of ingested foreign bodies


2010 ◽  
Vol 63 (3-4) ◽  
pp. 254-257 ◽  
Author(s):  
Goran Pudar ◽  
Ljiljana Vlaski

Introduction A retrospective study of Rigid Esophagoscopy, with the suspect of foreign body, was performed in General Hospital Zrenjanin 'Djordje Joanovic', at the Department of Otorhinolaryngology during the period of 1988 - 2007. Results and discussion The result of 517 esophagoscopies performed in the above period was 203 (39.26%) foreign bodies, with the average of 7,8 annually per 100.000 inhabitants. The patients age ranged from 1 to 91 years, (X = 48.98). Considering the gender, there were 95 male patients (46,79%), and 108 female patients (53.21%). The highest number of foreign bodies was found in the patients from the age group 60-69, (43/22.15%). According to the structure type of foreign bodies the most frequent were bones of animal origin (86/42.36%), followed by meat bolus (67/33%), metal coins (23/11.33%), and bodies of vegetable origin (14/6.89%). Metal coins were most frequently found in the age group 1-9. In regard to the level at which a foreign body was found (described in 157 cases, (77.30%)), 94 (59.87%) were found at the pharyngoesophageal junction, 58 (36.94%) were found in middle constriction of oesophagus, and in the area of diaphragmatic constriction and cardia there were 5 (3.18%) cases. The efficiency of removing foreign bodies by rigid esophagoscopy in the above mentioned sample was 99.01% (201/203). In 2 cases (0.99%), due to the impaction of foreign body, the patients were referred to the higher referent tertiary unit institution. Conclusion Foreign bodies represent a constant casuistics in Zrenjanin Municipality, dominantly connected to work of an otorhinolaryngologist on duty. Rigid esophagoscopy is safe and efficient diagnostic and therapeutic method.


Author(s):  
Raquel Puig-Lozano ◽  
Antonio Fernández ◽  
Pedro Saavedra ◽  
Marisa Tejedor ◽  
Eva Sierra ◽  
...  

2009 ◽  
Vol 124 (2) ◽  
pp. 171-174 ◽  
Author(s):  
M Daniel ◽  
T Kamani ◽  
C Nogueira ◽  
M-C Jaberoo ◽  
P Conboy ◽  
...  

AbstractBackground:Perforation after pharyngo-oesophagoscopy is a serious complication, and its identification, through close patient monitoring, is essential. Yet little is known about when symptoms and signs develop, and thus how long any close monitoring should last.Aim:To examine the timing of individual symptoms and signs of perforation after rigid pharyngo-oesophagoscopy.Methodology:Three-centre, retrospective study.Results:Of 3459 patients undergoing rigid pharyngo-oesophagoscopy, 10 (0.29 per cent) developed perforations, nine of which were suspected intra-operatively. Symptoms and signs developed at 1.5 hours post-operatively at the earliest, and at 36 hours at the latest. Three patients were asymptomatic. The majority of procedures (n = 8) were undertaken for food bolus obstruction or foreign body ingestion.Conclusion:Pharyngo-oesophagoscopy for food bolus obstruction and foreign body ingestion accounts for a large number of perforations, but symptoms and signs may take longer than 24 hours to develop. A contrast swallow should be considered in high risk patients, and a high index of suspicion maintained in order to detect this complication.


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