scholarly journals Polycyclic aromatic hydrocarbons bioaccessibility in seafood: Culinary practices effects on dietary exposure

2018 ◽  
Vol 164 ◽  
pp. 165-172 ◽  
Author(s):  
Fabíola Helena dos Santos Fogaça ◽  
Cristina Soares ◽  
Marta Oliveira ◽  
Ricardo N. Alves ◽  
Ana L. Maulvault ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Minmin Wu ◽  
Zhonghuan Xia ◽  
Qianqian Zhang ◽  
Jing Yin ◽  
Yanchi Zhou ◽  
...  

In a market basket study made in Nanjing, China, in which the most common consumed nine kinds of vegetables foodstuffs were sampled, the contents of 16 polycyclic aromatic hydrocarbons (PAHs) were analyzed using gas chromatography with mass spectrometer detector (GC-MS). The results showed that the total amount of 16 PAHs was within the range of 60.5~312 ng g−1 (wet weight). The ranking of total concentrations for different types of vegetables in decreasing order was leafy vegetable, fruit vegetable, and rhizome vegetable. Source analysis suggested that coal, oil, or other incomplete combustion of biomass mainly contributed to the concentration of PAHs. The margin of exposure (MOE) approach with age/gender group-specific daily dietary exposure level was used to estimate the carcinogenic risk. The calculated total mean MOE in the case of BaP and PAH4 (sum of BaA, CHR, BbF, and BaP) was 14960 and 7723, respectively, for local residents. In addition, the MOEs in PAH4 for some groups of both male and female were below the critical limit of 10 000 proposed by EFSA. Therefore, health effect owing to the consumption of vegetables on local residents needs high concern.


2010 ◽  
Vol 29 (5) ◽  
pp. 532-545 ◽  
Author(s):  
Helen Connelly ◽  
Jay C. Means

Polycyclic aromatic hydrocarbons (PAH) have been demonstrated to affect immune system modulation. The freshwater species of fish, Lepomis macrochirus (bluegill), was employed to investigate the effects of a 14-day dietary exposure to PAH including 2-aminoanthracene (2-AA), 2-methylnaphthalene (2-MN), and 9,10-dimethylanthracene (9,10-DMA) and a mixture of these 3 compounds at a total dose of 3.1 ± 0.01 mg on lymphocyte proliferation stimulated with 3 mitogens (concanavalin A [Con A], phorbol ester, and calcium ionophore). 2-Aminoanthracene was mitogenic itself and with added mitogens. 2-Methylnaphthalene induced some stimulatory and some inhibitory effects upon cell proliferation by Con A. 9,10-DMA and the mixture each suppressed cell proliferation. The mixture was highly suppressive to lymphocytes. Intracellular baseline calcium levels were reduced, possibly as a step prior to cell death. All PAH compounds tested were immunomodulatory to bluegill lymphocytes. Bluegill were demonstrated to have utility as a biomarker species for investigation of immunotoxicity.


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